Page last updated: 2024-12-07

1-pyrenyloxirane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

## 1-Pyrenyloxirane: A Versatile Building Block for Advanced Materials

1-Pyrenyloxirane is a **heterocyclic organic compound** containing both a pyrene unit and an oxirane ring. It's essentially a pyrene molecule with an epoxide group attached, giving it a unique combination of properties.

**Key Features:**

* **Pyrene:** This aromatic polycyclic hydrocarbon contributes fluorescence, strong UV absorption, and hydrophobic properties.
* **Oxirane:** The three-membered ring is reactive and can readily undergo ring-opening reactions, allowing for the introduction of various functional groups.

**Importance in Research:**

1-Pyrenyloxirane serves as a versatile building block for the synthesis of a wide range of functional materials, including:

* **Polymers:** By incorporating 1-pyrenyloxirane into polymer chains, researchers can create materials with enhanced fluorescence, UV absorption, and hydrophobic properties. This has applications in:
* **Sensors:** Detecting specific molecules or changes in the environment through fluorescence quenching or shifts.
* **Optical devices:** Creating materials with desired light absorption and emission properties for applications in lasers, LEDs, and waveguides.
* **Organic electronics:** Enhancing the performance of transistors, solar cells, and other electronic devices.

* **Dendrimers:** These highly branched molecules can be synthesized using 1-pyrenyloxirane as a monomer unit, allowing for the creation of:
* **Drug delivery systems:** Targeting specific cells or tissues and improving drug efficacy.
* **Gene delivery vectors:** Facilitating the efficient delivery of genetic material for gene therapy.
* **Catalysis:** Providing a high density of active sites for accelerating chemical reactions.

* **Biomaterials:** 1-Pyrenyloxirane can be incorporated into biocompatible materials for applications in:
* **Tissue engineering:** Creating scaffolds that promote cell growth and differentiation.
* **Bioimaging:** Visualizing cellular processes and structures through fluorescence microscopy.
* **Bioconjugation:** Attaching bioactive molecules to biocompatible surfaces for targeted drug delivery or diagnostic purposes.

**Key Advantages:**

* **Versatile functionality:** The combination of the pyrene unit and the reactive oxirane ring provides a unique platform for creating materials with diverse functionalities.
* **High fluorescence:** The pyrene moiety imparts strong fluorescence, enabling sensitive detection and analysis.
* **Ease of modification:** The oxirane ring readily undergoes ring-opening reactions, allowing for the introduction of a wide range of functional groups.

**Overall, 1-pyrenyloxirane plays a crucial role in the development of advanced materials with diverse applications in various fields, including medicine, biotechnology, and materials science.**

1-pyrenyloxirane: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID100333
SCHEMBL ID1129522
MeSH IDM0068665

Synonyms (12)

Synonym
brn 1379195
1-oxiranylpyrene
pyrene, 1-epoxyethyl-
1-pyrenyloxirane
oxirane, 1-pyrenyl-
nsc-289903
nsc289903
61695-74-7
5-17-02-00469 (beilstein handbook reference)
nsc 289903
SCHEMBL1129522
DTXSID30919378
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.66 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]