Page last updated: 2024-12-07
1-pyrenyloxirane
Description
## 1-Pyrenyloxirane: A Versatile Building Block for Advanced Materials
1-Pyrenyloxirane is a **heterocyclic organic compound** containing both a pyrene unit and an oxirane ring. It's essentially a pyrene molecule with an epoxide group attached, giving it a unique combination of properties.
**Key Features:**
* **Pyrene:** This aromatic polycyclic hydrocarbon contributes fluorescence, strong UV absorption, and hydrophobic properties.
* **Oxirane:** The three-membered ring is reactive and can readily undergo ring-opening reactions, allowing for the introduction of various functional groups.
**Importance in Research:**
1-Pyrenyloxirane serves as a versatile building block for the synthesis of a wide range of functional materials, including:
* **Polymers:** By incorporating 1-pyrenyloxirane into polymer chains, researchers can create materials with enhanced fluorescence, UV absorption, and hydrophobic properties. This has applications in:
* **Sensors:** Detecting specific molecules or changes in the environment through fluorescence quenching or shifts.
* **Optical devices:** Creating materials with desired light absorption and emission properties for applications in lasers, LEDs, and waveguides.
* **Organic electronics:** Enhancing the performance of transistors, solar cells, and other electronic devices.
* **Dendrimers:** These highly branched molecules can be synthesized using 1-pyrenyloxirane as a monomer unit, allowing for the creation of:
* **Drug delivery systems:** Targeting specific cells or tissues and improving drug efficacy.
* **Gene delivery vectors:** Facilitating the efficient delivery of genetic material for gene therapy.
* **Catalysis:** Providing a high density of active sites for accelerating chemical reactions.
* **Biomaterials:** 1-Pyrenyloxirane can be incorporated into biocompatible materials for applications in:
* **Tissue engineering:** Creating scaffolds that promote cell growth and differentiation.
* **Bioimaging:** Visualizing cellular processes and structures through fluorescence microscopy.
* **Bioconjugation:** Attaching bioactive molecules to biocompatible surfaces for targeted drug delivery or diagnostic purposes.
**Key Advantages:**
* **Versatile functionality:** The combination of the pyrene unit and the reactive oxirane ring provides a unique platform for creating materials with diverse functionalities.
* **High fluorescence:** The pyrene moiety imparts strong fluorescence, enabling sensitive detection and analysis.
* **Ease of modification:** The oxirane ring readily undergoes ring-opening reactions, allowing for the introduction of a wide range of functional groups.
**Overall, 1-pyrenyloxirane plays a crucial role in the development of advanced materials with diverse applications in various fields, including medicine, biotechnology, and materials science.**
1-pyrenyloxirane: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
PubMed CID | 100333 |
SCHEMBL ID | 1129522 |
MeSH ID | M0068665 |
Synonyms (12)
Synonym |
brn 1379195 |
1-oxiranylpyrene |
pyrene, 1-epoxyethyl- |
1-pyrenyloxirane |
oxirane, 1-pyrenyl- |
nsc-289903 |
nsc289903 |
61695-74-7 |
5-17-02-00469 (beilstein handbook reference) |
nsc 289903 |
SCHEMBL1129522 |
DTXSID30919378 |
Research
Studies (5)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 5 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.66
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 12.66 (24.57) | Research Supply Index | 1.79 (2.92) | Research Growth Index | 4.45 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |