Page last updated: 2024-11-12

1-palmitoyl-2-linoleoyl-3-acetyl-rac glycerol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1-palmitoyl-2-linoleoyl-3-acetyl-rac glycerol: occurs naturally in various seed oils, in bovine udder and in milk fat, and has been isolated from the antlers of sika deer (Cervus nippon TEMMENICK); these antlers have been used as a tonics in oriental medicine [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9960925
CHEMBL ID157366
SCHEMBL ID974869
MeSH IDM0470932

Synonyms (31)

Synonym
CHEMBL157366
ec-18
mosedipimod
1-palmitoyl-2-linoleoyl-3-acetyl-glycerol
GAKUNXBDVGLOFS-DUZKARGPSA-N
1-palmitoyl-2-linoleoyl-3-acetylglycerol
SCHEMBL974869
ec-18 cpd
221139-79-3
plag, (+/-)
who 10702
pla-racglycerol
mosedipimod [usan]
unii-88928bs57e
1-palmitoyl-2-linoleoyl-3-acetyl-rac glycerol
9,12-octadecadienoic acid (9z,12z)-, 1-((acetyloxy)methyl)-2-((1-oxohexadecyl)oxy)ethyl ester
1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol
88928bs57e ,
mosedipimod [inn]
mosedipimod [who-dd]
plag, (+/-)-
(1-acetyloxy-3-hexadecanoyloxypropan-2-yl) (9z,12z)-octadeca-9,12-dienoate
DB12592
D11668
mosedipimod (usan/inn)
Q27269906
plag
GLXC-25910
AKOS040748955
HY-109094
CS-0039395

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
"The purpose of this study was to assess the impact of inorganic mesoporous carriers on the physicochemical properties and oral bioavailability of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG)-loaded solid self-emulsifying drug delivery system (solid SEDDS)."( Effect of inorganic mesoporous carriers on 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol-loaded solid self-emulsifying drug delivery system: Physicochemical characterization and bioavailability in rats.
Choi, HG; Jin, SG; Kim, DS; Kim, JO; Li, DX; Oh, KT; Yang, ES; Yong, CS; Youn, YS, 2017
)
0.46
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID224782Compound was tested in vitro for its ability to increase the rate of [Ca+2] mobilization in pancreatic acinar cells1999Bioorganic & medicinal chemistry letters, Jan-04, Volume: 9, Issue:1
Monoacetyldiglycerides as new Ca2+ mobilizing agents in rat pancreatic acinar cells.
AID224780Compound was tested in vitro for its ability to increase [Ca+2] in pancreatic acinar cells at a concentration of 0.01 mg/mL. 1999Bioorganic & medicinal chemistry letters, Jan-04, Volume: 9, Issue:1
Monoacetyldiglycerides as new Ca2+ mobilizing agents in rat pancreatic acinar cells.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (19)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (5.26)18.2507
2000's2 (10.53)29.6817
2010's11 (57.89)24.3611
2020's5 (26.32)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 17.67

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index17.67 (24.57)
Research Supply Index3.00 (2.92)
Research Growth Index5.48 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (17.67)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other19 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]