Page last updated: 2024-12-08

1-palmitoyl-2-(1'-pyreneoctanoyl)glycero-3-phosphochine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

You seem to be describing a **phospholipid** called **1-palmitoyl-2-(1'-pyreneoctanoyl)glycero-3-phosphocholine**, often abbreviated as **POPC**. This is not the same as what you initially wrote, but I'm assuming you're referring to POPC.

Here's what you need to know about POPC:

**What it is:**

* **Phospholipid:** A type of lipid molecule that forms the structural basis of cell membranes.
* **1-palmitoyl-2-(1'-pyreneoctanoyl)glycero-3-phosphocholine:** This name tells us the specific components of the molecule:
* **1-palmitoyl:** A saturated fatty acid chain called palmitate at the first carbon position.
* **2-(1'-pyreneoctanoyl):** An unsaturated fatty acid chain with a pyrene fluorophore attached at the second carbon position.
* **glycero-3-phosphocholine:** The backbone of the phospholipid, consisting of glycerol (a three-carbon alcohol) linked to a phosphate group and a choline molecule.

**Importance in Research:**

POPC is used extensively in research for several reasons:

* **Membrane Model:** It's a good model for studying cell membranes because it's a major component of many biological membranes.
* **Fluorescence:** The pyrene group attached to the fatty acid chain allows researchers to use fluorescence spectroscopy to study the properties of membranes. This means they can track:
* **Membrane fluidity:** How easily lipids move within the membrane.
* **Lipid interactions:** How different lipid molecules interact with each other.
* **Protein-lipid interactions:** How proteins interact with lipids in the membrane.
* **Drug Development:** POPC is used in studying the effects of drugs and other compounds on membranes, helping to understand how they might interact with cells.

**Additional Information:**

* **Variations:** There are many variations of POPC with different fatty acid chains or fluorophores attached. Each variation can be useful for studying specific aspects of membrane behavior.
* **Methods:** POPC is often used in conjunction with other techniques, such as liposome formation, microscopy, and spectroscopy, to gain a deeper understanding of membrane function.

If you're interested in learning more about POPC or its use in research, I recommend searching for more information using specific keywords such as POPC fluorescence, POPC membrane fluidity, or POPC drug delivery.

1-palmitoyl-2-(1'-pyreneoctanoyl)glycero-3-phosphochine: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID196328
SCHEMBL ID10702198
MeSH IDM0172915

Synonyms (15)

Synonym
95864-17-8
[(2r)-3-hexadecanoyloxy-2-(10-pyren-1-yldecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
1-palmitoyl-2-pyrenedecanoylphosphatidylcholine
1-palmitoyl-2-(1'-pyreneoctanoyl)glycero-3-phosphochine
ppogp
1-palmitoyl-2-(pyrene-1-yl)decanoyl-sn-glycero-3-phosphocholine
SCHEMBL10702198
10-pyrene-pc
AKOS027382982
DTXSID40914778
3-(hexadecanoyloxy)-2-{[10-(pyren-1-yl)decanoyl]oxy}propyl 2-(trimethylazaniumyl)ethyl phosphate
1-palmitoyl-2-pyrenedecanoyl phosphatidylcholine
VDA86417
l-alpha-phosphatidylcholine,beta-(pyren-1-yl)decanoyl-gamma-palmitoyl
PD021043
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (38)

TimeframeStudies, This Drug (%)All Drugs %
pre-199011 (28.95)18.7374
1990's19 (50.00)18.2507
2000's7 (18.42)29.6817
2010's1 (2.63)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 10.74

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index10.74 (24.57)
Research Supply Index3.66 (2.92)
Research Growth Index4.40 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (10.74)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other38 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]