Page last updated: 2024-12-11

1-oleoyl lysophosphatidylcholine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

## 1-Oleoyl Lysophosphatidylcholine (LysoPC)

1-Oleoyl lysophosphatidylcholine, often shortened to LysoPC, is a **phospholipid** that plays a crucial role in various cellular processes. It is composed of:

* **Glycerol:** A 3-carbon alcohol backbone.
* **Phosphorylcholine:** A phosphate group linked to choline.
* **Oleic acid:** A monounsaturated fatty acid.

**LysoPC is a key component of cell membranes** and is involved in:

* **Membrane fluidity and permeability:** LysoPC can influence the fluidity and permeability of cell membranes, impacting how molecules move across them.
* **Signal transduction:** LysoPC can act as a signaling molecule, triggering various intracellular pathways.
* **Cell growth and differentiation:** LysoPC has been shown to play a role in regulating cell growth and differentiation in various tissues.
* **Immune response:** LysoPC can modulate immune cell activity and the inflammatory response.
* **Lipid metabolism:** LysoPC is an intermediate in the synthesis and degradation of other phospholipids.

**Importance for Research:**

LysoPC is a fascinating molecule with a wide range of biological activities. This makes it an attractive target for research in various fields:

* **Drug discovery:** LysoPC has been investigated as a potential therapeutic agent for diseases like cancer, inflammation, and neurodegenerative disorders.
* **Cell biology:** LysoPC serves as a valuable tool for studying cell membrane dynamics, signaling pathways, and lipid metabolism.
* **Biochemistry:** LysoPC provides a model system for studying the structure and function of phospholipids.
* **Biomaterials:** LysoPC is being explored for its potential in developing biocompatible materials and drug delivery systems.
* **Food science:** LysoPC is found in various foods and has been linked to positive effects on human health.

**Current Research:**

Researchers are actively investigating the role of LysoPC in:

* **Cancer:** LysoPC has been shown to have both anti-cancer and pro-cancer effects depending on the context.
* **Neurological disorders:** LysoPC is implicated in neuronal signaling and has been investigated for its potential role in Alzheimer's disease and other neurological conditions.
* **Inflammation:** LysoPC can contribute to both the development and resolution of inflammation.
* **Cardiovascular diseases:** LysoPC has been linked to both protective and detrimental effects on the cardiovascular system.

**Overall, LysoPC is a complex and multifaceted molecule with vast implications for human health and disease.** Continued research into its various roles will provide valuable insights into fundamental cellular processes and pave the way for new therapeutic approaches.

Cross-References

ID SourceID
PubMed CID6449974
MeSH IDM0220546

Synonyms (16)

Synonym
pc(18:1/0:0)[rac]
LMGP01050114
3-oleoyl-rac-glycerol-1-phosphorylcholine
pc(18:1(9z)/0:0)[rac]
1-oleoyl-lysopc
1-(cis-9-octadecenoyl)-sn-glycero-3-phosphocholine
3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium, 4,7-dihydroxy-n,n,n-trimethyl-10-oxo-, hydroxide, inner salt, 4-oxide, (z)-
1-ogpc
3542-29-8
1-oleoylglycerophosphocholine
1-oleoyl lysophosphatidylcholine
[2-hydroxy-3-[(z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
oleoyl lysophosphatidylcholine
DTXSID201305217
compound np-013871
AKOS040738913
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.50 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.29 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]