Page last updated: 2024-12-11
1-oleoyl lysophosphatidylcholine
## 1-Oleoyl Lysophosphatidylcholine (LysoPC)
1-Oleoyl lysophosphatidylcholine, often shortened to LysoPC, is a **phospholipid** that plays a crucial role in various cellular processes. It is composed of:
* **Glycerol:** A 3-carbon alcohol backbone.
* **Phosphorylcholine:** A phosphate group linked to choline.
* **Oleic acid:** A monounsaturated fatty acid.
**LysoPC is a key component of cell membranes** and is involved in:
* **Membrane fluidity and permeability:** LysoPC can influence the fluidity and permeability of cell membranes, impacting how molecules move across them.
* **Signal transduction:** LysoPC can act as a signaling molecule, triggering various intracellular pathways.
* **Cell growth and differentiation:** LysoPC has been shown to play a role in regulating cell growth and differentiation in various tissues.
* **Immune response:** LysoPC can modulate immune cell activity and the inflammatory response.
* **Lipid metabolism:** LysoPC is an intermediate in the synthesis and degradation of other phospholipids.
**Importance for Research:**
LysoPC is a fascinating molecule with a wide range of biological activities. This makes it an attractive target for research in various fields:
* **Drug discovery:** LysoPC has been investigated as a potential therapeutic agent for diseases like cancer, inflammation, and neurodegenerative disorders.
* **Cell biology:** LysoPC serves as a valuable tool for studying cell membrane dynamics, signaling pathways, and lipid metabolism.
* **Biochemistry:** LysoPC provides a model system for studying the structure and function of phospholipids.
* **Biomaterials:** LysoPC is being explored for its potential in developing biocompatible materials and drug delivery systems.
* **Food science:** LysoPC is found in various foods and has been linked to positive effects on human health.
**Current Research:**
Researchers are actively investigating the role of LysoPC in:
* **Cancer:** LysoPC has been shown to have both anti-cancer and pro-cancer effects depending on the context.
* **Neurological disorders:** LysoPC is implicated in neuronal signaling and has been investigated for its potential role in Alzheimer's disease and other neurological conditions.
* **Inflammation:** LysoPC can contribute to both the development and resolution of inflammation.
* **Cardiovascular diseases:** LysoPC has been linked to both protective and detrimental effects on the cardiovascular system.
**Overall, LysoPC is a complex and multifaceted molecule with vast implications for human health and disease.** Continued research into its various roles will provide valuable insights into fundamental cellular processes and pave the way for new therapeutic approaches.
Cross-References
ID Source | ID |
PubMed CID | 6449974 |
MeSH ID | M0220546 |
Synonyms (16)
Synonym |
pc(18:1/0:0)[rac] |
LMGP01050114 |
3-oleoyl-rac-glycerol-1-phosphorylcholine |
pc(18:1(9z)/0:0)[rac] |
1-oleoyl-lysopc |
1-(cis-9-octadecenoyl)-sn-glycero-3-phosphocholine |
3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium, 4,7-dihydroxy-n,n,n-trimethyl-10-oxo-, hydroxide, inner salt, 4-oxide, (z)- |
1-ogpc |
3542-29-8 |
1-oleoylglycerophosphocholine |
1-oleoyl lysophosphatidylcholine |
[2-hydroxy-3-[(z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate |
oleoyl lysophosphatidylcholine |
DTXSID201305217 |
compound np-013871 |
AKOS040738913 |
Research
Studies (5)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (60.00) | 18.2507 |
2000's | 2 (40.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.50
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 12.50 (24.57) | Research Supply Index | 1.79 (2.92) | Research Growth Index | 4.29 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |