Page last updated: 2024-12-08

1-o-indol-3-ylacetylglucose

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

1-O-indol-3-ylacetylglucose, also known as **IAA-glucose**, is a **conjugate of indole-3-acetic acid (IAA) and glucose**.

Here's a breakdown of its components and why it's important in research:

**Components:**

* **Indole-3-acetic acid (IAA):** This is a key plant hormone, specifically an auxin, involved in various processes like cell division, elongation, root development, and fruit ripening.
* **Glucose:** A simple sugar that acts as a primary energy source for plants and is also involved in various metabolic pathways.

**Formation and Significance:**

Plants often conjugate IAA with glucose to form IAA-glucose. This conjugation serves several important purposes:

* **Storage and Transport:** IAA-glucose acts as a storage form of IAA, allowing the plant to store and transport the hormone efficiently.
* **Regulation of IAA Activity:** The conjugation process effectively inactivates the hormone, keeping it in a non-active form. This allows plants to regulate IAA levels and prevent excessive hormone activity.
* **Protection from Degradation:** Conjugation also protects IAA from enzymatic degradation, ensuring its availability for future use.

**Importance in Research:**

IAA-glucose is a crucial molecule for understanding plant hormone regulation and its role in various developmental processes. Researchers study IAA-glucose for several reasons:

* **Understanding IAA Metabolism:** Studying the formation, breakdown, and transport of IAA-glucose provides insights into how plants regulate IAA levels and activity.
* **Developmental Processes:** IAA-glucose plays a critical role in various developmental processes like root formation, shoot growth, and fruit development. Studying its role in these processes can lead to better understanding of plant growth and development.
* **Agricultural Applications:** Knowledge about IAA-glucose and its role in plant growth can be applied to improve agricultural practices, including optimizing fertilization, plant breeding, and crop yield.
* **Environmental Stress Response:** IAA-glucose is also involved in plant responses to environmental stress, such as drought and salinity. Studying its role in these responses can help understand how plants adapt to changing environments.

In summary, 1-O-indol-3-ylacetylglucose, or IAA-glucose, is a crucial molecule involved in plant hormone regulation and has significant implications for various areas of research, including plant development, agricultural applications, and environmental stress responses.

Cross-References

ID SourceID
PubMed CID440255
CHEBI ID17990
MeSH IDM0112263

Synonyms (25)

Synonym
indole-3-acetyl-beta-1-d-glucoside
C04197 ,
1-o-(indol-3-yl)acetyl-beta-d-glucose
1-o-(indole-3-acetyl)-beta-1-d-glucose
19817-95-9
iaa-glucose
1-o-indol-3-ylacetyl-beta-d-glucose
CHEBI:17990
1-o-indol-3-ylacetylglucose
1-o-(1h-indol-3-ylacetyl)-beta-d-glucopyranose
beta-d-glucopyranose, 1-(1h-indole-3-acetate)
indole-3-acetic acid beta-d-glucoside
indole-3-acetyl-beta-1-d-glucose
1-o-(indol-3-ylacetyl)-beta-d-glucose
[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] 2-(1h-indol-3-yl)acetate
indole-3-acetyl beta-d-glucopyranose
DTXSID50173536
AKOS030254713
J-012801
Q27102748
1-(1h-indole-3-acetate) beta-d-glucopyranose
indole-3-acetic acid beta-glucoside
indole-3-acetyl beta -d-glucopyranose
4-o-(indole-3-acetyl)-d-glucopyranose
(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl 2-(1h-indol-3-yl)acetate
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
indolyl carbohydrate
indoleacetic acid ester conjugateA conjugate of indole-3-acetic acid with sugars or polyols via an oxygen bridge.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (4)

PathwayProteinsCompounds
indole-3-acetate activation II09
superpathway of indole-3-acetate conjugate biosynthesis828
indole-3-acetate inactivation IX017
indole-3-acetate activation II011
superpathway of indole-3-acetate conjugate biosynthesis533
IAA conjugation I010

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (42.86)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.24

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.24 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.24)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]