1-chlorohexadecane is an organic compound with the chemical formula CH3(CH2)14CH2Cl. It's essentially a long chain of 16 carbon atoms with a chlorine atom attached to the first carbon. Here's why it's important for research:
**Properties:**
* **Long hydrophobic chain:** The presence of the long hydrocarbon chain makes 1-chlorohexadecane highly hydrophobic (water-repelling).
* **Reactive chlorine:** The chlorine atom at the end makes it reactive and allows for further modifications or reactions.
* **Solid at room temperature:** Its solid form makes it easier to handle and use in various experiments.
**Research Applications:**
* **Surfactant and Detergent Synthesis:** 1-chlorohexadecane is used as a starting material to synthesize various surfactants and detergents. The long chain provides the hydrophobic portion, while the reactive chlorine can be modified to introduce hydrophilic groups.
* **Polymers and Coatings:** It serves as a building block in the synthesis of polymers and coatings due to its long chain and reactive nature. This property allows for the creation of materials with desired properties like water resistance and hydrophobicity.
* **Lipid Mimics:** 1-chlorohexadecane can mimic the properties of lipids, making it valuable for studying cell membranes and their interactions with other molecules. It can also be used in drug delivery research to encapsulate and deliver therapeutic agents.
* **Biofuel Research:** Its long hydrocarbon chain makes it relevant to research on biofuels, particularly in the development of synthetic diesel fuels.
* **Organic Chemistry Experiments:** Due to its relatively simple structure and predictable reactivity, 1-chlorohexadecane is often used in organic chemistry experiments to study reactions involving alkyl halides.
**Overall, 1-chlorohexadecane is a versatile compound that finds applications in diverse research areas, ranging from materials science to biochemistry. Its unique properties make it a valuable tool for developing new products and exploring fundamental scientific principles.**
ID Source | ID |
---|---|
PubMed CID | 20993 |
CHEMBL ID | 3184566 |
SCHEMBL ID | 437217 |
MeSH ID | M0119048 |
Synonym |
---|
AKOS009031446 |
nsc43727 |
nsc-43727 |
4860-03-1 |
1-chlorohexadecane |
cetyl chloride |
nsc-57106 |
nsc57106 |
hexadecane, 1-chloro- |
hexadecyl chloride |
n-hexadecyl chloride |
1-chlorohexadecane, 95% |
NCIOPEN2_002284 |
palmityl chloride |
NCGC00260297-01 |
cas-4860-03-1 |
dtxsid3027580 , |
dtxcid107580 |
tox21_202749 |
A827568 |
1-chloro-hexadecane |
nsc 57106 |
unii-wq5zks3ek3 |
einecs 225-461-7 |
wq5zks3ek3 , |
FT-0623575 |
1-hexadecyl chloride |
SCHEMBL437217 |
CHEMBL3184566 |
J-520013 |
mfcd00000959 |
1-chlorohexadecane, purum, >=97.0% (gc) |
Q27292774 |
chloro hexadecane |
CS-W012500 |
EN300-19716 |
Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
AR protein | Homo sapiens (human) | Potency | 12.6213 | 0.0002 | 21.2231 | 8,912.5098 | AID1259243; AID1259247; AID1259381 |
progesterone receptor | Homo sapiens (human) | Potency | 3.8352 | 0.0004 | 17.9460 | 75.1148 | AID1346784 |
estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 9.6336 | 0.0015 | 30.6073 | 15,848.9004 | AID1224841 |
estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 12.2373 | 0.0002 | 29.3054 | 16,493.5996 | AID743075 |
Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 1.3608 | 0.0023 | 19.5956 | 74.0614 | AID651631 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 2 (40.00) | 18.7374 |
1990's | 2 (40.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (27.96) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |