Page last updated: 2024-12-10

1-butyl-3-methylpyridinium

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1-butyl-3-methylpyridinium (BMP) is a quaternary ammonium compound with a pyridinium ring. It's not a naturally occurring compound, but rather a synthetic molecule that has gained attention in research due to its unique properties and applications in various fields. Here's a breakdown:

**Structure and Properties:**

* **Structure:** BMP consists of a pyridine ring with a butyl group attached at the 1 position and a methyl group at the 3 position. The presence of the positively charged nitrogen atom makes it a cation.
* **Properties:** BMP is a colorless, crystalline solid with a melting point around 115-118°C. It's soluble in water and many organic solvents. The positively charged nitrogen atom makes it an excellent electrophile, capable of reacting with nucleophiles.

**Research Importance:**

BMP has garnered significant attention in research due to its roles in:

1. **Organic Synthesis:**
* **Alkylation and Acylation Reactions:** The electrophilic nature of BMP makes it a versatile reagent for alkylation and acylation reactions. It can be used to introduce alkyl or acyl groups to various substrates, leading to the synthesis of new organic compounds.
* **Catalyst:** BMP can act as a catalyst in certain organic reactions, promoting specific transformations. Its role in catalysis stems from its ability to activate reactants and facilitate bond formation.

2. **Materials Science:**
* **Ionic Liquids:** BMP is a key component in the formation of ionic liquids, which are salts that melt at low temperatures. These liquids have unique properties like high ionic conductivity, low vapor pressure, and high thermal stability, making them promising candidates for applications in energy storage, catalysis, and separations.
* **Electrolytes:** BMP's ionic nature makes it a potential electrolyte for batteries and fuel cells. Its ability to conduct electricity efficiently and its stability under various conditions make it a valuable component in these energy-related applications.

3. **Biomedical Research:**
* **Pharmacology:** BMP has been investigated for its potential therapeutic effects. It has shown activity against certain types of cancer cells, making it a promising candidate for drug development. However, its toxicity and potential side effects need further investigation.
* **Neurobiology:** BMP is related to some compounds found in the brain and has been studied in relation to neurological conditions like Alzheimer's disease. However, its exact role in the brain and its potential therapeutic benefits need further research.

**Overall:**

1-butyl-3-methylpyridinium is a versatile compound with potential applications in various fields, from organic synthesis to materials science and even biomedical research. Further research is ongoing to understand its full potential and to develop safe and effective applications for this intriguing molecule.

1-butyl-3-methylpyridinium: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID3510569
CHEMBL ID1194342
SCHEMBL ID296028
MeSH IDM0533903

Synonyms (5)

Synonym
CHEMBL1194342
125867-77-8
SCHEMBL296028
1-butyl-3-methylpyridinium
DTXSID40393180

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" A simplified central composite design (SCCD) was employed to design the concentration distribution of components in binary mixtures to effectively detect the possible toxic interactions between pesticide and IL over the whole concentration range."( Effect of ionic liquid on the toxicity of pesticide to Vibrio-qinghaiensis sp.-Q67.
Liu, HL; Liu, SS; Zhang, J, 2009
)
0.35
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.43

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.43 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.37 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.43)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]