Page last updated: 2024-12-09

1-butyl-3-methylimidazolium trifluoromethanesulfonate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

## 1-Butyl-3-methylimidazolium trifluoromethanesulfonate: A Promising Ionic Liquid

**1-Butyl-3-methylimidazolium trifluoromethanesulfonate**, often abbreviated as **[BMIM][OTf]**, is an **ionic liquid**, meaning it's a salt that exists as a liquid at room temperature. It's composed of two ions:

* **1-Butyl-3-methylimidazolium cation**: A positively charged organic molecule with a bulky structure.
* **Trifluoromethanesulfonate anion**: A negatively charged inorganic molecule with a smaller size and high charge density.

**Why is it important for research?**

[BMIM][OTf] has gained significant interest in diverse fields due to its unique properties, including:

* **High thermal stability:** It can withstand high temperatures without decomposing, making it suitable for various applications, such as high-temperature reactions and catalysis.
* **Low vapor pressure:** It's practically non-volatile at room temperature, reducing environmental concerns associated with traditional organic solvents.
* **Excellent solvent properties:** It dissolves a wide range of organic and inorganic compounds, acting as a versatile medium for various reactions and processes.
* **Wide electrochemical window:** It allows for electrochemical reactions to occur at a wider potential range compared to conventional solvents.
* **Tunable properties:** The structure of both cation and anion can be modified to fine-tune its physical and chemical properties, making it adaptable to specific applications.

**Key research areas where [BMIM][OTf] plays a role:**

* **Catalysis:** As a solvent, [BMIM][OTf] can enhance the catalytic activity of various reactions, offering a greener alternative to traditional organic solvents.
* **Electrochemistry:** Its wide electrochemical window and good ionic conductivity make it ideal for developing new electrochemical devices, such as batteries, fuel cells, and sensors.
* **Material synthesis:** It serves as a reaction medium for synthesizing a variety of materials, including polymers, nanomaterials, and organic-inorganic hybrids.
* **Biotechnology:** Its biocompatibility and ability to dissolve biomolecules makes it a promising solvent for enzyme reactions and biocatalysis.
* **Separations:** It can be used as an extraction solvent for separating different components in complex mixtures, offering a more efficient and environmentally friendly alternative to conventional methods.

**Overall, 1-butyl-3-methylimidazolium trifluoromethanesulfonate is a versatile and environmentally friendly ionic liquid with potential applications in numerous research areas. Its unique properties make it a valuable tool for developing sustainable technologies and solutions for a wide range of challenges.**

1-butyl-3-methylimidazolium trifluoromethanesulfonate: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID2734246
CHEMBL ID3183478
SCHEMBL ID192398
MeSH IDM0526061

Synonyms (34)

Synonym
1-butyl-3-methylimidazolium trifluoromethanesulfonate, >=95.0% (h-nmr)
174899-66-2
1-butyl-3-methylimidazolium trifluoromethanesulfonate
b2337 ,
nsc746783
nsc-746783
NCGC00260167-01
tox21_202619
dtxsid0049232 ,
dtxcid2029088
cas-174899-66-2
1-butyl-3-methylimidazolium trifluoromethansulfonate
FT-0608143
AKOS015904066
bmim otf
SCHEMBL192398
1-butyl-3-methylimidazolium triflate
1-butyl-3-methylimidazoliumtrifluoromethanesulfonate
Q-102679
CHEMBL3183478
1-butyl-3-methylimidazolium trifluoromethanesulfonate, 97%
mfcd03427620
SY062306
1-butyl-3-methyl-imidazol-3-ium trifluoromethanesulfonate
BS-16059
1-butyl-3-methylimidazol-3-ium;trifluoromethanesulfonate
1-butyl-3-methyl-1h-imidazol-3-ium trifluoromethanesulfonate
AC8235
1-n-butyl-3-methylimidazolium triflate
A881651
1-butyl-3-methylimidazolium trifluoromethansulfonate [bmim]otf
1-butyl-3-methylimidazolium trifluoromethanesulphonate
nsc 746783
CS-W012210
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (3)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
acetylcholinesteraseHomo sapiens (human)Potency63.57060.002541.796015,848.9004AID1347395
GLI family zinc finger 3Homo sapiens (human)Potency15.43340.000714.592883.7951AID1259369
nuclear factor erythroid 2-related factor 2 isoform 1Homo sapiens (human)Potency68.93850.000627.21521,122.0200AID743202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's8 (80.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 23.78

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index23.78 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.63 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (23.78)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]