Page last updated: 2024-12-05

1,5-dichloroanthraquinone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

## 1,5-Dichloroanthraquinone: A Versatile Molecule for Research

1,5-dichloroanthraquinone is a **yellow, crystalline organic compound** with the chemical formula C14H6Cl2O2. It is a derivative of anthraquinone, a molecule known for its applications in dyes and pigments.

Here's why 1,5-dichloroanthraquinone is important for research:

**1. Synthetic versatility:**

* **Precursor for other valuable compounds:** 1,5-dichloroanthraquinone serves as a starting material for synthesizing various other anthraquinone derivatives. These derivatives exhibit a wide range of properties and applications, including dyes, pigments, pharmaceuticals, and organic electronics.
* **Reaction versatility:** The chlorine atoms on the molecule provide opportunities for various chemical reactions, making it a versatile building block for synthesizing complex organic molecules.

**2. Applications in Materials Science:**

* **Organic electronics:** 1,5-dichloroanthraquinone and its derivatives have shown promise in organic electronic applications like organic field-effect transistors (OFETs) and organic solar cells. Their unique electronic properties and ability to form stable films make them attractive candidates for these technologies.
* **Polymers and composites:** Incorporation of 1,5-dichloroanthraquinone or its derivatives into polymers can enhance their physical and chemical properties, improving their performance in various applications.

**3. Biological activity:**

* **Antimicrobial and antiviral properties:** Some anthraquinone derivatives, including those derived from 1,5-dichloroanthraquinone, have shown antimicrobial and antiviral activity. This opens up possibilities for developing new drugs to combat infectious diseases.
* **Photodynamic therapy (PDT):** Certain anthraquinone derivatives exhibit photodynamic properties, making them potential candidates for PDT treatment of cancer. These derivatives can generate reactive oxygen species upon light activation, effectively killing cancer cells.

**4. Environmental applications:**

* **Dye degradation:** 1,5-dichloroanthraquinone can be used as a photocatalyst to degrade dyes and pollutants in wastewater. Its ability to absorb sunlight and generate reactive species promotes efficient dye degradation.

**5. Other research areas:**

* **Analytical chemistry:** 1,5-dichloroanthraquinone can be used as a fluorescent probe for detecting specific analytes.
* **Catalysis:** Its ability to act as a catalyst in various organic reactions makes it relevant for the development of sustainable and efficient chemical processes.

In conclusion, 1,5-dichloroanthraquinone is a versatile and valuable molecule with applications in diverse fields. Its unique chemical structure and reactivity make it an essential tool for researchers exploring new technologies, developing novel materials, and understanding complex biological processes.

Cross-References

ID SourceID
PubMed CID6711
SCHEMBL ID125609
MeSH IDM0489371

Synonyms (48)

Synonym
EU-0066588
CBMICRO_015239
1,5-dichloro-9,10-anthraquinone
einecs 201-424-0
1,5-dichloranthrachinon [czech]
ai3-38301
nsc 13969
anthraquinone, 1,5-dichloro-
82-46-2
9, 1,5-dichloro-
wln: l c666 bv ivj dg kg
1,5-dichloranthrachinon
nsc13969
anthraquinone,5-dichloro-
1,5-dichloroanthraquinone ,
nsc-13969
1,5-dichloroanthracene-9,10-dione
1,5-dichloroantraquinone
9,10-anthracenedione, 1,5-dichloro-
1,5-dichloroanthra-9,10-quinone
inchi=1/c14h6cl2o2/c15-9-5-1-3-7-11(9)14(18)8-4-2-6-10(16)12(8)13(7)17/h1-6
BIM-0015275.P001
1,5-dichloroanthraquinone, 96%
MAYBRIDGE1_002222
SR-01000631719-1
STK054157
AC-11726
D0328
HMS547M22
AKOS001583243
CCG-41659
unii-s335v6mf9e
s335v6mf9e ,
FT-0606954
SCHEMBL125609
1,5-dichloro-9,10-anthracenedione
1,5-bischloroanthraquinone
1,5-dichloro anthraquinone
1, 5-dichloroanthraquinone
DTXSID3058874
W-104174
1,5-dichloroanthra-9,10-quinone #
mfcd00001190
1,5-dichloro-9,10-dihydroanthracene-9,10-dione
1,5-dichloro-anthraquinone
AS-14370
Q27288514
CS-W012310
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).2014Journal of biomolecular screening, Jul, Volume: 19, Issue:6
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 24.77

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index24.77 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index5.08 (4.65)
Search Engine Demand Index23.28 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (24.77)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]