Page last updated: 2024-12-05

1,5-bis(p-aminophenoxy)pentane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

## 1,5-bis(p-aminophenoxy)pentane: A versatile building block for research

1,5-bis(p-aminophenoxy)pentane is a **bifunctional molecule**, meaning it contains two reactive groups that can be utilized for various chemical reactions. It consists of a **pentane chain** (five carbon atoms) with two **para-aminophenoxy** groups attached at either end.

**Why is it important for research?**

This molecule possesses several key features that make it valuable in various research fields:

* **Versatile synthetic intermediate:** The aminophenoxy groups serve as **reactive sites** for various chemical transformations. They can be easily modified through reactions like **acylation, alkylation, or coupling reactions** to introduce different functionalities. This versatility allows for the creation of a wide range of novel compounds with specific properties.
* **Building block for polymers:** The two aminophenoxy groups can undergo **polymerization reactions**, leading to the formation of **polymers with unique properties**. This enables the development of new materials with desired characteristics like conductivity, thermal stability, and mechanical strength.
* **Potential for drug discovery:** The aminophenoxy groups can be modified to create **pharmacologically active compounds**. They can be used as **scaffolds** for developing new drugs targeting specific receptors or enzymes.
* **Applications in materials science:** 1,5-bis(p-aminophenoxy)pentane can be incorporated into **organic electronic materials** and **nanomaterials** due to its ability to act as a **linker** between different components. This allows for the design of new materials with improved electrical conductivity and optical properties.

**Specific research areas where 1,5-bis(p-aminophenoxy)pentane plays a role:**

* **Polymer chemistry:** Development of new polymers for various applications including electronics, biomaterials, and coatings.
* **Medicinal chemistry:** Synthesis of novel drug candidates for different therapeutic areas.
* **Materials science:** Fabrication of advanced materials with tailored electrical, optical, and mechanical properties.
* **Organic synthesis:** Development of new synthetic methods and strategies utilizing the versatility of the molecule.

In conclusion, 1,5-bis(p-aminophenoxy)pentane is a valuable research tool due to its unique structure and reactivity. Its potential applications extend across several disciplines, highlighting its importance in driving innovation in various scientific fields.

1,5-bis(p-aminophenoxy)pentane: retinotoxic drug; RN given refers to parent cpd; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID14173
SCHEMBL ID562258
MeSH IDM0040873

Synonyms (22)

Synonym
4,4'-(1,5-pentanediyl)dioxydianiline
4-[5-(4-aminophenoxy)pentoxy]aniline
[4-[5-(4-azaniumylphenoxy)pentoxy]phenyl]azanium dichloride
AKOS024348895
1,5-bis(p-aminophenoxy)pentane
4,4'-(1,5-pentanediylbis(oxy))bisbenzenamine
2391-56-2
1,5-di(p-aminophenoxy)pentane
1,5-bis(4-aminophenoxy)pentane
SCHEMBL562258
SLHXQWDUYXSTPA-UHFFFAOYSA-N
4,4'-(pentane-1,5-diylbis(oxy))dianiline
DTXSID70178624
benzenamine, 4,4'-[1,5-pentanediylbis(oxy)]bis-, dihydrochloride
benzenamine, 4,4'-[1,5-pentanediylbis(oxy)]bis-
4-{[5-(4-aminophenoxy)pentyl]oxy}phenylamine
mfcd01632139
1,5-bis(4-amino-benzene-1-oxy)pentane
CS-0336279
SB82281
AS-75615
PD160505
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.51

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.51 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.31 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.51)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]