Page last updated: 2024-12-05

1,4-butanediol dimethacrylate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

## 1,4-Butanediol Dimethacrylate (BDDMA) Explained

1,4-Butanediol dimethacrylate (BDDMA) is a **monomer**, meaning it is a small molecule that can react with other monomers to form long chains, called polymers. BDDMA is specifically a **cross-linking monomer**, meaning it has two reactive sites, allowing it to connect different polymer chains together, creating a **network structure**.

**Why is BDDMA important for research?**

BDDMA is crucial in various research fields due to its role in creating **highly stable and durable materials**. Here's a breakdown:

* **Biomedical Applications:**
* **Dental Materials:** BDDMA is used in **dental resins and composites**, making them strong and resistant to wear and tear. It also improves their biocompatibility and adhesion to teeth.
* **Tissue Engineering:** It's used in **hydrogels** for 3D cell culture and tissue regeneration. Its cross-linking properties allow for the creation of porous and biocompatible scaffolds that mimic the natural environment of tissues.
* **Drug Delivery:** BDDMA is incorporated in **microspheres and nanoparticles**, enabling controlled release of medications and targeted drug delivery.
* **Materials Science:**
* **Polymers:** BDDMA contributes to the development of **high-performance polymers** with improved mechanical strength, thermal stability, and resistance to chemicals.
* **Coatings:** It is used in **protective coatings** for various surfaces, providing resistance to scratches, abrasions, and environmental factors.
* **Other Applications:**
* **Adhesives:** BDDMA enhances the adhesion of adhesives, leading to stronger bonds and improved performance.
* **Optoelectronics:** Its unique optical properties are utilized in the development of **optical fibers and other light-guiding materials**.

**Importance in Research:**

BDDMA's versatility and unique properties make it a vital component in research across various disciplines. Its potential for creating innovative and functional materials drives advancements in:

* **Biomedical Engineering:** Developing new materials for implants, drug delivery, and regenerative medicine.
* **Materials Science:** Discovering new polymers with tailored properties for specific applications.
* **Chemistry:** Understanding the mechanisms of cross-linking reactions and polymer network formation.
* **Nanotechnology:** Designing and manufacturing nanomaterials with unique properties.

**Overall, 1,4-butanediol dimethacrylate plays a significant role in expanding the possibilities of creating advanced materials with diverse functionalities, making it a key ingredient in research and technological innovation.**

Cross-References

ID SourceID
PubMed CID16387
CHEMBL ID3184875
SCHEMBL ID25426
MeSH IDM0268831

Synonyms (49)

Synonym
1,4-butylene glycol dimethacrylate
tetramethylene dimethacrylate
1,4-butanediol dimethacrylate, 95%, contains 200-300 ppm mehq as inhibitor
hsdb 5467
1,4-butanediol dimethacrylate
butylene dimethacrylate
2-propenoic acid, 2-methyl-, 1,4-butanediyl ester
tetramethylene methacrylate
tetramethylene glycol dimethacrylate
x 970
1,4-butylene dimethacrylate
oligotetramethylene glycol dimethacrylate
ccris 7046
einecs 218-218-1
methacrylic acid, tetramethylene ester
4-(2-methylprop-2-enoyloxy)butyl 2-methylprop-2-enoate
2082-81-7
FT-0650574
kx6732he0u ,
2-propenoic acid, 2-methyl-, 1,1'-(1,4-butanediyl) ester
unii-kx6732he0u
ec 218-218-1
tox21_301681
dtxsid4044870 ,
butane-1,4-diyl bis(2-methylprop-2-enoate)
cas-2082-81-7
dtxcid2024870
NCGC00256263-01
AM84724
AKOS015902993
1,4-butanediol dimethacrylate [inci]
1,4-butanediol dimethacrylate [hsdb]
SCHEMBL25426
4-(methacryloyloxy)butyl 2-methylacrylate #
CHEMBL3184875
butane-1,4-diyl bis(2-methylacrylate)
mfcd00008594
tetramethylene glycol dimethacrylate (stabilized with mehq)
J-013661
1,4-butanediol dimethacrylate(6.4cp(20 degrees c))
1,4-butanediol dimethacrylate,min. 90%
T3488
Q27282479
A852249
D92705
1,4-butanediol dimethacrylate 100 microg/ml in acetonitrile
CAA08281
4-[(2-methylprop-2-enoyl)oxy]butyl 2-methylprop-2-enoate
CS-W010428
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (3)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
LuciferasePhotinus pyralis (common eastern firefly)Potency89.35840.007215.758889.3584AID1224835
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency1.53550.001723.839378.1014AID743083
thyroid stimulating hormone receptorHomo sapiens (human)Potency0.61130.001628.015177.1139AID1259385
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (18)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's14 (77.78)29.6817
2010's3 (16.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other20 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]