Compounds > 1,3-bis(diphenylphosphino)propane
Page last updated: 2024-11-06

1,3-bis(diphenylphosphino)propane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1,3-bis(diphenylphosphino)propane: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID81219
CHEMBL ID73394
SCHEMBL ID35092
MeSH IDM0441670

Synonyms (80)

Synonym
AC-4967
44r56e2c68 ,
propane-1,3-diylbis(diphenylphosphine)
einecs 229-791-2
phosphine, 1,1'-(1,3-propanediyl)bis(1,1-diphenyl-
unii-44r56e2c68
nsc 193753
phosphine, 1,3-propanediylbis(diphenyl-
dppp cpd
6737-42-4
phosphine, trimethylenebis[diphenyl-
trimethylenebis(diphenylphosphine)
1,3-bis(diphenylphosphino)propane
phosphine,3-propanediylbis[diphenyl-
nsc-193753
nsc193753
1,3-propanediylbis[diphenylphosphine]
bis(1,3-diphenylphosphino)propane
1,3-bis(diphenylphosphino)propane, 97%
B1138
CHEMBL73394
3-diphenylphosphanylpropyl(diphenyl)phosphane
3-diphenylphosphanylpropyl(diphenyl)phosphane;dppp, 1,3-bis(diphenylphosphino)propane
A835727
AKOS004909020
[3-(diphenylphosphanyl)propyl]diphenylphosphane
FT-0606575
GC10105
1,3-bis(diphenylphosphino)propane (dppp)
phosphine, 1,3-propanediylbis[diphenyl-
1,3-bis-(diphenylphosphino)propane
SCHEMBL35092
SY006192
mfcd00003050
1,3-bis(diphenylphosphino)-propane
1,3-bisdiphenylphosphinopropane
1,3-bis(diphenyl phosphino)propane
1-((3-(diphenylphosphino)propyl)(phenyl)phosphino)benzene
1,3-bis(diphenyphosphino)propane
1.3-bis-diphenylphosphinopropane
1,3-bis(di-phenyl-phosphino)propane
1,3-bis-(diphenylphosphino)-propane
propane-1,3-diylbis(diphenyl phosphine)
1,3-bis diphenylphosphinopropane
1,3-bis-(diphenylphosphine) propane
1,3-bis(diphenyl-phosphino)propane
1,3-bis(diphenyl-phospino)propane
1,3-bis-(diphenylphosphine)propane
3-diphenylphosphanylpropyl-diphenyl-phosphane
1,3-bis(diphenylphospino)propane
1,3bis(diphenylphosphino)propane
propane-1,3-diylbis(diphenylphosphane)
1,3 bis(diphenylphosphino)propane
1,3-bis (diphenylphosphino) propane
1,3-bis(diphenylphophino)propane
1,3-bis(diphenylphosphine)-propane
1,3-bis(diphenylphosphine)propane
1,3-bis (diphenylphosphino)-propane
1,3-propanediylbis(diphenylphosphine)
1,3-bis-diphenylphosphinopropane
1,3-bis(diphenylphosphino) propane
1,3-bis (diphenylphosphino)propane
1,3bis-(diphenylphosphino)propane
DTXSID0064464
dppp [mi]
1,3-propylenebis(diphenylphosphine)
W-104717
STR02861
FD14028
phosphine, trimethylenebis(diphenyl-
[3-(diphenylphosphino)propyl](diphenyl)phosphine #
CS-W008852
BBL101642
F0001-1778
STL555438
BCP04337
Q161494
AMY19792
EN300-53864
PD159807
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID153809Maximum increase in life span was determined against P388 leukemia at 4-5 doses of compound1987Journal of medicinal chemistry, Dec, Volume: 30, Issue:12
Antitumor activity of bis(diphenylphosphino)alkanes, their gold(I) coordination complexes, and related compounds.
AID38071In vitro cytotoxicity against murine B16 melanoma cells1987Journal of medicinal chemistry, Dec, Volume: 30, Issue:12
Antitumor activity of bis(diphenylphosphino)alkanes, their gold(I) coordination complexes, and related compounds.
AID115142Maximally tolerated dose was measured after ip administration of compound, 24 hr after tumor implantation.1987Journal of medicinal chemistry, Dec, Volume: 30, Issue:12
Antitumor activity of bis(diphenylphosphino)alkanes, their gold(I) coordination complexes, and related compounds.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (7.69)18.7374
1990's0 (0.00)18.2507
2000's4 (30.77)29.6817
2010's8 (61.54)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 30.04

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index30.04 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index36.71 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (30.04)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
bromide
Bromides: Salts of hydrobromic acid, HBr, with the bromine atom in the 1- oxidation state. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)		2.1110halide anion;
monoatomic bromine
salicylic acid
Scalp: The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendinous galea aponeurotica; loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).		2.0810monohydroxybenzoic acidalgal metabolite;
antifungal agent;
antiinfective agent;
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor;
keratolytic drug;
plant hormone;
plant metabolite
dimethyl sulfoxide
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.. dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.		2.0510sulfoxide;
volatile organic compound		alkylating agent;
antidote;
Escherichia coli metabolite;
geroprotector;
MRI contrast agent;
non-narcotic analgesic;
polar aprotic solvent;
radical scavenger
hydrogen
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.. dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.		2.1110elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
methanol
Methanol: A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.. primary alcohol : A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.. methanol : The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.		2.0610alkyl alcohol;
one-carbon compound;
primary alcohol;
volatile organic compound		amphiprotic solvent;
Escherichia coli metabolite;
fuel;
human metabolite;
mouse metabolite;
Mycoplasma genitalium metabolite
nickel
Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.. nickel ion : A nickel atom having a net electric charge.. nickel atom : Chemical element (nickel group element atom) with atomic number 28.		2.7830metal allergen;
nickel group element atom		epitope;
micronutrient
phenol
[no description available]		2.0610phenolsantiseptic drug;
disinfectant;
human xenobiotic metabolite;
mouse metabolite
boranes
Boranes: The collective name for the boron hydrides, which are analogous to the alkanes and silanes. Numerous boranes are known. Some have high calorific values and are used in high-energy fuels. (From Grant & Hackh's Chemical Dictionary, 5th ed). borane : The simplest borane, consisting of a single boron atom carrying three hydrogens.. boranes : The molecular hydrides of boron.		2.0610boranes;
mononuclear parent hydride
propane
Propane: A three carbon alkane with the formula H3CCH2CH3.		8.92120alkane;
gas molecular entity		food propellant
benzyl chloride
benzyl chloride: RN given refers to unlabeled cpd. chlorophenylmethane : A chlorohydrocarbon that is phenylmethane substituted by a chloro group at unspecified position.. benzyl chloride : A member of the class of benzyl chlorides that is toluene substituted on the alpha-carbon with chlorine.		2.0810benzyl chlorides
4-methylpyridine
4-methylpyridine: structure in first source. 4-methylpyridine : A methylpyridine in which the methyl substituent is at position 4.		2.0510methylpyridine
2-hydroxypyridine
hydroxypyridine : Any member of the class of pyridines with at least one hydroxy substituent.. pyridin-2-ol : A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 2.		2.0810monohydroxypyridineplant metabolite
oxazoles
Oxazoles: Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions.. 1,3-oxazole : A five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3.. oxazole : An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom.		2.06101,3-oxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
indoline
indoline: structure given in first source		2.0510indoles
4-phenylpyridine
[no description available]		2.0510phenylpyridine
tri-n-butylphosphine
[no description available]		2.0110
palladium
Palladium: A chemical element having an atomic weight of 106.4, atomic number of 46, and the symbol Pd. It is a white, ductile metal resembling platinum, and following it in abundance and importance of applications. It is used in dentistry in the form of gold, silver, and copper alloys.. palladium : Chemical element (nickel group element atom) with atomic number 46.		3.1450metal allergen;
nickel group element atom;
platinum group metal atom
gold
Gold: A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.		7.0610copper group element atom;
elemental gold
phosphine
phosphane : The simplest phosphine, consisting of a single phosphorus atom with three hydrogens attached.. phosphine : Phosphane (PH3) and compounds derived from it by substituting one, two or three hydrogen atoms by hydrocarbyl groups: RPH2, R2PH, R3P (R =/= H) are called primary, secondary and tertiary phosphines, respectively. A specific phosphine is preferably named as a substituted phosphane.		2.0610mononuclear parent hydride;
phosphanes;
phosphine		carcinogenic agent;
fumigant insecticide
1,2,3,4-tetrahydroquinoline
1,2,3,4-tetrahydroquinoline: structure in first source. 1,2,3,4-tetrahydroquinoline : A member of the class of quinolines that is the 1,2,3,4-tetrahydro derivative of quinoline.		2.0510quinolines
bis(diphenylphosphine)ethane
[no description available]		1.9710diphosphanes;
tertiary phosphine		allergen
organophosphonates
hydrogenphosphite : A divalent inorganic anion resulting from the removal of a proton from two of the hydroxy groups of phosphorous acid.		2.4620divalent inorganic anion;
phosphite ion
1,2-bis(diphenylphosphino)benzene
1,2-bis(diphenylphosphino)benzene: structure in first source		2.0510
oxazolidine
oxazolidine: structure given in first source		2.0610oxazolidine
sodium borohydride
sodium borohydride: RN given refers to parent cpd		2.0610inorganic sodium salt;
metal tetrahydridoborate
ConditionIndicatedRelationship StrengthStudiesTrials
Experimental Neoplasms
[description not available]		01.9710