Compounds > 1,3-benzothiazol-2-yl(thiomorpholin-4-yl)methanone
Page last updated: 2024-09-28

1,3-benzothiazol-2-yl(thiomorpholin-4-yl)methanone

Cross-References

ID SourceID
PubMed CID724614
CHEMBL ID1594644
CHEBI ID112409

Synonyms (19)

Synonym
SDCCGMLS-0045946.P002
IDI1_001882
MLS000063771
2-(4-thiomorpholinylcarbonyl)-1,3-benzothiazole
smr000075571
MAYBRIDGE2_000752
MIXCOM4_000138
SR-01000272295-3
STK155493
1,3-benzothiazol-2-yl(thiomorpholin-4-yl)methanone
CHEBI:112409
HMS2342L06
CCG-44413
AKOS005407479
CHEMBL1594644
Q27192513
SR-01000272295-1
sr-01000272295
1,3-benzothiazol-2-yl(thiomorpholino)methanone

Drug Classes (1)

ClassDescription
benzothiazoles
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (8)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
LuciferasePhotinus pyralis (common eastern firefly)Potency16.94410.007215.758889.3584AID588342
BRCA1Homo sapiens (human)Potency10.00000.89137.722525.1189AID624202
ATAD5 protein, partialHomo sapiens (human)Potency22.14270.004110.890331.5287AID504466; AID504467
P53Homo sapiens (human)Potency50.11870.07319.685831.6228AID504706
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1Homo sapiens (human)Potency8.91250.001815.663839.8107AID894
chromobox protein homolog 1Homo sapiens (human)Potency79.43280.006026.168889.1251AID540317
nuclear factor erythroid 2-related factor 2 isoform 2Homo sapiens (human)Potency7.07950.00419.984825.9290AID504444
ras-related protein Rab-9AHomo sapiens (human)Potency4.46680.00022.621531.4954AID485297
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (14)

Assay IDTitleYearJournalArticle
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID1297705Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 after 28 days by two-fold serial dilution method2016European journal of medicinal chemistry, Jun-30, Volume: 116Benzo[d]thiazol-2-yl(piperazin-1-yl)methanones as new anti-mycobacterial chemotypes: Design, synthesis, biological evaluation and 3D-QSAR studies.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
pyrazinamide[no description available]medium10monocarboxylic acid amide;
N-acylammonia;
pyrazines		antitubercular agent;
prodrug
ciprofloxacin[no description available]medium10aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion		antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic
isoniazid[no description available]medium10carbohydrazideantitubercular agent;
drug allergen
ethambutol[no description available]medium10ethanolamines;
ethylenediamine derivative		antitubercular agent;
environmental contaminant;
xenobiotic
bm 212[no description available]medium10
rifampin[no description available]medium10cyclic ketal;
hydrazone;
N-iminopiperazine;
N-methylpiperazine;
rifamycins;
semisynthetic derivative;
zwitterion		angiogenesis inhibitor;
antiamoebic agent;
antineoplastic agent;
antitubercular agent;
DNA synthesis inhibitor;
EC 2.7.7.6 (RNA polymerase) inhibitor;
Escherichia coli metabolite;
geroprotector;
leprostatic drug;
neuroprotective agent;
pregnane X receptor agonist;
protein synthesis inhibitor
ethoxzolamide[no description available]low00aromatic ether;
benzothiazoles;
sulfonamide		antiglaucoma drug;
diuretic;
EC 4.2.1.1 (carbonic anhydrase) inhibitor
riluzole[no description available]low00benzothiazoles
tiaramide[no description available]low00benzothiazoles
ticlatone[no description available]low00benzothiazoles
benzothiazole[no description available]low00benzothiazolesenvironmental contaminant;
plant metabolite;
xenobiotic
dibenzothiazyl disulfide[no description available]low00benzothiazoles;
organic disulfide		allergen
2-aminobenzothiazole[no description available]low00benzothiazoles
diamthazole[no description available]low00benzothiazoles
dithiazanine[no description available]low00benzothiazoles;
benzothiazolium ion		anthelminthic drug;
fluorochrome
2-(methylthio)benzothiazole[no description available]low00benzothiazoles;
methyl sulfide		aryl hydrocarbon receptor agonist;
xenobiotic metabolite
2-(2-hydroxyphenyl)benzothiazole[no description available]low00benzothiazoles;
phenols		geroprotector
methabenzthiazuron[no description available]low00benzothiazoles
sabeluzole[no description available]low00benzothiazoles
lubeluzole[no description available]low00benzothiazoles
2-benzothiazolesulfonamide[no description available]low00benzothiazoles;
sulfonamide
tioxidazole[no description available]low00benzothiazoles
2-(4-Morpholinyl)benzothiazole[no description available]low00benzothiazoles
mefenacet[no description available]low00benzothiazoles;
tertiary carboxamide		antimitotic;
herbicide
firefly luciferin[no description available]low001,3-thiazolemonocarboxylic acid;
benzothiazoles;
imidothioate		luciferin
pramipexole[no description available]low00benzothiazoles;
diamine		antidyskinesia agent;
antiparkinson drug;
dopamine agonist;
radical scavenger
N-(4-methoxyphenyl)-1,3-benzothiazol-2-amine[no description available]low00benzothiazoles
2-pyridin-4-yl-1,3-benzothiazole[no description available]low00benzothiazoles
6-methoxy-3-methyl-1,3-benzothiazol-2-imine[no description available]low00benzothiazoles
6-Fluoro-1,3-benzothiazol-2-amine[no description available]low00benzothiazoles
N-[2-(1-azepanyl)-1,3-benzothiazol-6-yl]carbamic acid ethyl ester[no description available]low00benzothiazoles
e 3040[no description available]low00benzothiazoles;
organic hydroxy compound;
pyridines;
secondary amino compound		anti-inflammatory drug;
EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor;
uricosuric drug
E3040 glucuronide[no description available]low00benzothiazoles;
beta-D-glucosiduronic acid;
pyridines;
secondary amino compound		xenobiotic metabolite
3-(3,5-dimethyl-1-pyrazolyl)-1,2-benzothiazole 1,1-dioxide[no description available]low00benzothiazoles
6-ethoxy-2-[(4-fluorophenyl)methylthio]-1,3-benzothiazole[no description available]low00benzothiazoles
6-propan-2-yl-1,3-benzothiazol-2-amine[no description available]low00benzothiazoles
3-(2-phenoxyethyl)-1,3-benzothiazol-2-one[no description available]low00benzothiazoles
3-[3-(2-methoxyphenoxy)propyl]-1,3-benzothiazol-2-one[no description available]low00benzothiazoles
2-(2-oxo-1,3-benzothiazol-3-yl)-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide[no description available]low00benzothiazoles
N-(1,3-benzothiazol-2-yl)-N-methylbenzamide[no description available]low00benzothiazoles
2-[(1-cyclohexyl-5-tetrazolyl)thio]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide[no description available]low00benzothiazoles
2-(1,3-benzothiazol-2-yl)-3-methyl-2-butenenitrile[no description available]low00benzothiazoles
5-[(4-chloro-1-pyrazolyl)methyl]-N-(6-methyl-1,3-benzothiazol-2-yl)-2-furancarboxamide[no description available]low00benzothiazoles
N-(2-furanylmethyl)-2-(2-oxo-1,3-benzothiazol-3-yl)acetamide[no description available]low00benzothiazoles
N-(6-ethoxy-1,3-benzothiazol-2-yl)-2-methoxyacetamide[no description available]low00benzothiazoles
N-(5-methoxy-1,3-benzothiazol-2-yl)-3-methylbutanamide[no description available]low00benzothiazoles
2-(4,5-dihydrothiazol-2-ylthio)-N-(6-methoxy-1,3-benzothiazol-2-yl)acetamide[no description available]low00benzothiazoles
2-(beta-D-glucosyl)benzothiazole[no description available]low00benzothiazoles;
C-glycosyl compound
1-[(1,3-benzothiazol-2-ylthio)methyl]-2-azepanone[no description available]low00benzothiazoles
2-[[3-[4-(dimethylamino)phenyl]-4,5-dihydroisoxazol-5-yl]methyl]-1,1-dioxo-1,2-benzothiazol-3-one[no description available]low00benzothiazoles
5-[(1,3-benzothiazol-2-ylthio)methyl]-2-furancarboxylic acid methyl ester[no description available]low00benzothiazoles
N-(4,6-dimethyl-2-pyrimidinyl)-1,3-benzothiazol-2-amine[no description available]low00benzothiazoles
captax[no description available]low00aryl thiol;
benzothiazoles		carcinogenic agent;
metabolite
N-[[(6-methyl-1,3-benzothiazol-2-yl)amino]-sulfanylidenemethyl]-2-thiophenecarboxamide[no description available]low00benzothiazoles
2-(1,3-benzothiazol-2-ylmethoxy)phenol[no description available]low00benzothiazoles
N-[2-(1-cyclohexenyl)ethyl]-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide[no description available]low00benzothiazoles
N-(4-methyl-2-thiazolyl)-3-(2-oxo-1,3-benzothiazol-3-yl)propanamide[no description available]low00benzothiazoles
N-(1,3-benzothiazol-2-yl)-2-cyclohexylacetamide[no description available]low00benzothiazoles
N-(3-phenyl-1,3-benzothiazol-2-ylidene)-2-propenamide[no description available]low00benzothiazoles
N-(4-methoxyphenyl)-3-methyl-1,3-benzothiazol-2-imine[no description available]low00benzothiazoles
N-(6-ethoxy-1,3-benzothiazol-2-yl)butanamide[no description available]low00benzothiazoles
N-[[(6-methoxy-1,3-benzothiazol-2-yl)amino]-sulfanylidenemethyl]-2-furancarboxamide[no description available]low00benzothiazoles
2-[(2-chlorophenyl)methylthio]-6-nitro-1,3-benzothiazole[no description available]low00benzothiazoles
N-(1,3-benzothiazol-2-yl)-2-[(1-methyl-2-imidazolyl)thio]acetamide[no description available]low00benzothiazoles
N-[4,6-bis(4-morpholinyl)-1,3,5-triazin-2-yl]-2-(methylthio)-1,3-benzothiazol-6-amine[no description available]low00benzothiazoles
2-[[cyclohexyl(oxo)methyl]amino]-1,3-benzothiazole-6-carboxylic acid methyl ester[no description available]low00benzothiazoles
N-(2-methyl-1,3-benzothiazol-6-yl)-2-furancarboxamide[no description available]low00benzothiazoles
2-(2,4,5-trimethoxyphenyl)-1,3-benzothiazole[no description available]low00benzothiazoles
3-[2-(3-methylphenoxy)ethyl]-1,3-benzothiazol-2-one[no description available]low00benzothiazoles
3-[2-(4-methylphenoxy)ethyl]-1,3-benzothiazol-2-one[no description available]low00benzothiazoles
3-methoxy-N-(6-methylsulfonyl-1,3-benzothiazol-2-yl)benzamide[no description available]low00benzothiazoles
N-(6-ethoxy-1,3-benzothiazol-2-yl)-1,3-dimethyl-2-oxo-5-benzimidazolesulfonamide[no description available]low00benzothiazoles
N-[6-(diethylsulfamoyl)-1,3-benzothiazol-2-yl]-2-thiophenecarboxamide[no description available]low00benzothiazoles
2-[(3-bromo-2-imidazo[1,2-a]pyrimidinyl)methylthio]-1,3-benzothiazole[no description available]low00benzothiazoles
N-(6-chloro-1,3-benzothiazol-2-yl)-2-diphenylphosphorylacetamide[no description available]low00benzothiazoles
3-[(1,3-benzothiazol-2-ylthio)methyl]-4-cyclohexyl-1H-1,2,4-triazole-5-thione[no description available]low00benzothiazoles
6-fluoro-2-phenyl-1,2-benzothiazol-3-one[no description available]low00benzothiazoles
6-fluoro-2-(2-methylphenyl)-1,2-benzothiazol-3-one[no description available]low00benzothiazoles
1-[[2-(1,3-benzothiazol-2-ylthio)-1-oxoethyl]amino]-3-phenylthiourea[no description available]low00benzothiazoles
1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(1,3-benzothiazol-2-ylthio)methyl]-4-triazolecarboxylic acid methyl ester[no description available]low00benzothiazoles
[4-methoxy-6-(propan-2-ylamino)-1,3,5-triazin-2-yl]-[(1,1,3-trioxo-1,2-benzothiazol-2-yl)methyl]cyanamide[no description available]low00benzothiazoles
[4-chloro-6-(propan-2-ylamino)-1,3,5-triazin-2-yl]-[(1,1,3-trioxo-1,2-benzothiazol-2-yl)methyl]cyanamide[no description available]low00benzothiazoles
(4,7-dichloro-1,3-benzothiazol-2-yl)hydrazine[no description available]low00benzothiazoles
3,4,5-trimethoxy-N-(3-methyl-1,3-benzothiazol-2-ylidene)benzamide[no description available]low00benzothiazoles
4-(1,3-benzothiazol-2-ylthio)butanoic acid [2-[(3-cyano-2-thiophenyl)amino]-2-oxoethyl] ester[no description available]low00benzothiazoles
N-[2-(1,3-benzothiazol-2-ylthio)-1-oxoethyl]-1-methyl-2-pyrrolecarboxamide[no description available]low00benzothiazoles
3-(1,3-benzothiazol-2-yl)propanoic acid (3,5-dimethyl-4-isoxazolyl)methyl ester[no description available]low00benzothiazoles
1-(1,3-benzothiazol-2-yl)-3-propylurea[no description available]low00benzothiazoles
5-bromo-N-(6-sulfamoyl-1,3-benzothiazol-2-yl)-2-furancarboxamide[no description available]low00benzothiazoles
N-(4,7-dimethoxy-3-methyl-1,3-benzothiazol-2-ylidene)butanamide[no description available]low00benzothiazoles
N-(4-fluoro-3-methyl-1,3-benzothiazol-2-ylidene)-2-nitrobenzamide[no description available]low00benzothiazoles
5-bromo-N-(4,7-dimethoxy-1,3-benzothiazol-2-yl)-2-thiophenecarboxamide[no description available]low00benzothiazoles
N-[2-(methylthio)-1,3-benzothiazol-6-yl]-2-furancarboxamide[no description available]low00benzothiazoles
1-cyclohexyl-3-(6-ethoxy-1,3-benzothiazol-2-yl)urea[no description available]low00benzothiazoles
5-bromo-N-(4-methoxy-1,3-benzothiazol-2-yl)-2-thiophenecarboxamide[no description available]low00benzothiazoles
2-(1,3-benzothiazol-2-yl)-5-methyl-3-pyrazolamine[no description available]low00benzothiazoles
2-[5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl(oxo)methyl]-1,1-dioxo-1,2-benzothiazol-3-one[no description available]low00benzothiazoles
N-(6-methylsulfonyl-1,3-benzothiazol-2-yl)-4-oxo-4-thiophen-2-ylbutanamide[no description available]low00benzothiazoles
N-(2-phenylethyl)-1,3-benzothiazol-2-amine[no description available]low00benzothiazoles
N-(4,5,6-trifluoro-1,3-benzothiazol-2-yl)-2-furancarboxamide[no description available]low00benzothiazoles
4-[[5-(1,3-benzothiazol-2-yl)-2-thiophenyl]-oxomethyl]-1-piperazinecarboxaldehyde[no description available]low00benzothiazoles
1,3-benzothiazole-6-carboxylic acid (2-benzamido-2-oxoethyl) ester[no description available]low00benzothiazoles
1,3-benzothiazole-6-carboxylic acid [2-[(3,5-dichloro-4-methyl-2-pyridinyl)amino]-2-oxoethyl] ester[no description available]low00benzothiazoles
1,3-benzothiazole-6-carboxylic acid [2-(2-furanyl)-2-oxoethyl] ester[no description available]low00benzothiazoles
1-(1,1-dioxo-1,2-benzothiazol-3-yl)-N-(2-methylphenyl)-4-piperidinecarboxamide[no description available]low00benzothiazoles
N-(2-methyl-1,3-benzothiazol-6-yl)benzamide[no description available]low00benzothiazoles
2-(2-chloro-3-pyridinyl)-1,3-benzothiazole[no description available]low00benzothiazoles
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-methyl-1,2,4-triazol-3-yl]thio]-N-[2-(4-morpholinyl)ethyl]acetamide[no description available]low00benzothiazoles
N-[6-(dimethylsulfamoyl)-1,3-benzothiazol-2-yl]-2-thiophenecarboxamide[no description available]low00benzothiazoles
1,3-benzothiazole-6-carboxylic acid [2-[1-(1-methoxypropan-2-yl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] ester[no description available]low00benzothiazoles
N-(3-methyl-1,3-benzothiazol-2-ylidene)-2-pyrazinecarboxamide[no description available]low00benzothiazoles
2-(6-imidazo[2,1-b]thiazolyl)acetic acid [2-(1,3-benzothiazol-2-ylamino)-2-oxoethyl] ester[no description available]low00benzothiazoles
N-(1,3-benzothiazol-2-yl)-2-oxolanecarboxamide[no description available]low00benzothiazoles
1-(2-furanylmethyl)-N-[2-(methylthio)-1,3-benzothiazol-6-yl]-5-oxo-3-pyrrolidinecarboxamide[no description available]low00benzothiazoles
1-thiophen-2-ylsulfonyl-4-piperidinecarboxylic acid 1,3-benzothiazol-2-ylmethyl ester[no description available]low00benzothiazoles
N-(1,3-benzothiazol-2-yl)-2-methoxy-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]benzamide[no description available]low00benzothiazoles
4-[[2-(4-methyl-1-piperidinyl)-1,3-benzothiazol-6-yl]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester[no description available]low00benzothiazoles
2-[(6-fluoro-1,3-benzothiazol-2-yl)amino]-4-thiazolecarboxylic acid ethyl ester[no description available]low00benzothiazoles
4-(4,6-difluoro-1,3-benzothiazol-2-yl)morpholine[no description available]low00benzothiazoles
5-bromo-2-thiophenecarboxylic acid 1,3-benzothiazol-2-ylmethyl ester[no description available]low00benzothiazoles
N-(6-acetamido-3-prop-2-enyl-1,3-benzothiazol-2-ylidene)cyclohexanecarboxamide[no description available]low00benzothiazoles
N-(6-acetamido-3-prop-2-enyl-1,3-benzothiazol-2-ylidene)-2-thiophenecarboxamide[no description available]low00benzothiazoles
2-chloro-N-(3-methyl-1,3-benzothiazol-2-ylidene)acetamide[no description available]low00benzothiazoles
2-(1,3-benzothiazol-2-ylmethylthio)-1-butyl-5-benzimidazolesulfonamide[no description available]low00benzothiazoles
N-(5-phenyl-1,3,4-oxadiazol-2-yl)-1,3-benzothiazole-2-carboxamide[no description available]low00benzothiazoles
3-methoxy-N-(3-methyl-6-methylsulfonyl-1,3-benzothiazol-2-ylidene)benzamide[no description available]low00benzothiazoles
[4-(butan-2-ylamino)-6-chloro-1,3,5-triazin-2-yl]-[(1,1,3-trioxo-1,2-benzothiazol-2-yl)methyl]cyanamide[no description available]low00benzothiazoles
N-[3-(2-methoxyethyl)-6-methylsulfonyl-1,3-benzothiazol-2-ylidene]-2-nitrobenzamide[no description available]low00benzothiazoles
N'-(4,6-difluoro-1,3-benzothiazol-2-yl)benzohydrazide[no description available]low00benzothiazoles
3-chloro-N-[3-(2-methoxyethyl)-6-sulfamoyl-1,3-benzothiazol-2-ylidene]-1-benzothiophene-2-carboxamide[no description available]low00benzothiazoles
N-(7-methyl-2-thiazolo[4,5-g][1,3]benzothiazolyl)propanamide[no description available]low00benzothiazoles
N-[3-(2-methylcyclohexyl)-2,4-dihydro-1H-1,3,5-triazin-6-yl]-1,3-benzothiazol-2-amine[no description available]low00benzothiazoles
N-(6-fluoro-1,3-benzothiazol-2-yl)-2-oxolanecarboxamide[no description available]low00benzothiazoles
N-(6-methyl-1,3-benzothiazol-2-yl)-6-oxo-1-phenyl-4,5-dihydropyridazine-3-carboxamide[no description available]low00benzothiazoles
4-[[1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-piperidinyl]-oxomethyl]-1-piperazinecarboxylic acid ethyl ester[no description available]low00benzothiazoles
2-[[4-methyl-5-[(2-oxo-1,3-benzothiazol-3-yl)methyl]-1,2,4-triazol-3-yl]thio]-N-(phenylmethyl)acetamide[no description available]low00benzothiazoles
N-(2-oxolanylmethyl)-2-(1-piperidinyl)-1,3-benzothiazole-6-carboxamide[no description available]low00benzothiazoles
N-(6-methyl-1,3-benzothiazol-2-yl)-2-(5,6,7,8-tetrahydro-4H-cyclohepta[c]pyrazol-2-yl)acetamide[no description available]low00benzothiazoles
N-(4-methyl-1,3-benzothiazol-2-yl)-2-(1-pyrrolyl)acetamide[no description available]low00benzothiazoles
dithiazanine iodide[no description available]low00benzothiazoles;
organic iodide salt		anthelminthic drug;
fluorochrome
3,3'-diethylthiacarbocyanine iodide[no description available]low00benzothiazoles;
cyanine dye		fluorochrome
tyrphostin ag825[no description available]low00aromatic ether;
benzothiazoles;
enamide;
nitrile;
organic sulfide;
phenols;
primary carboxamide		epidermal growth factor receptor antagonist
2-(1,3-benzothiazol-2-yl)-4-chloro-5-(3-chloroanilino)-3-pyridazinone[no description available]low00benzothiazoles
5-[(6-methoxy-1,3-benzothiazol-2-yl)amino]-3-methyl-2-thiophenecarboxylic acid ethyl ester[no description available]low00benzothiazoles
6-bromo-2-(1-pyrrolidinyl)-1,3-benzothiazole[no description available]low00benzothiazoles
6-fluoro-N-phenyl-1,3-benzothiazol-2-amine[no description available]low00benzothiazoles
N'-(4-fluoro-1,3-benzothiazol-2-yl)-2-phenoxyacetohydrazide[no description available]low00benzothiazoles
N'-(4,5-dimethyl-1,3-benzothiazol-2-yl)propanehydrazide[no description available]low00benzothiazoles
N'-(4,6-difluoro-1,3-benzothiazol-2-yl)propanehydrazide[no description available]low00benzothiazoles
4-fluoro-N-(4-fluoro-1,3-benzothiazol-2-yl)-1,3-benzothiazol-2-amine[no description available]low00benzothiazoles
N-[3-(dimethylamino)propyl]-N-(6-methyl-1,3-benzothiazol-2-yl)-1,3-benzothiazole-6-carboxamide[no description available]low00benzothiazoles
2-(3,5-dimethyl-1H-pyrrol-2-yl)-1,3-benzothiazole[no description available]low00benzothiazoles
N-(6-methoxy-1,3-benzothiazol-2-yl)-1-thiophen-2-ylsulfonyl-4-piperidinecarboxamide[no description available]low00benzothiazoles
r 115866[no description available]low00aromatic amine;
benzothiazoles;
secondary amino compound;
triazoles
as 601245[no description available]low00benzothiazoles
2-(4-methoxyphenyl)-1,2-benzothiazol-3-one[no description available]low00benzothiazoles
2-(4-chlorophenyl)-1,2-benzothiazol-3-one[no description available]low00benzothiazoles
tozadenant[no description available]low00benzothiazoles
3-(benzenesulfonyl)-N-[4-(6-methyl-1,3-benzothiazol-2-yl)phenyl]propanamide[no description available]low00benzothiazoles
2-(4-fluorophenyl)-6-methoxy-1,3-benzothiazole[no description available]low00benzothiazoles
2-(3-chlorophenyl)-1,2-benzothiazol-3-one[no description available]low00benzothiazoles
vizamyl[no description available]low00(18)F radiopharmaceutical;
aromatic amine;
benzothiazoles;
secondary amino compound		radioactive imaging agent
picogreen[no description available]low00benzothiazoles;
cyanine dye;
quinolines;
tertiary amine		fluorescent dye
N-[3-(3,5-dimethyl-1-piperidinyl)propyl]-2-(1-piperidinyl)-1,3-benzothiazole-6-carboxamide[no description available]low00benzothiazoles
5-fluoro-2-phenyl-1,2-benzothiazol-3-one[no description available]low00benzothiazoles
2-(2-fluorophenyl)-1,2-benzothiazol-3-one[no description available]low00benzothiazoles
2-(4-fluorophenyl)-1,2-benzothiazol-3-one[no description available]low00benzothiazoles
INDY[no description available]low00benzothiazoles;
enone;
organic hydroxy compound		antineoplastic agent;
drug metabolite;
EC 2.7.12.1 (dual-specificity kinase) inhibitor
2-(3-oxo-1,2-benzothiazol-2-yl)-N-phenylacetamide[no description available]low00benzothiazoles
tak-632[no description available]low00(trifluoromethyl)benzenes;
aromatic ether;
benzothiazoles;
cyclopropylcarboxamide;
monofluorobenzenes;
nitrile;
secondary carboxamide		antineoplastic agent;
apoptosis inducer;
B-Raf inhibitor;
EC 2.7.11.26 (tau-protein kinase) inhibitor;
necroptosis inhibitor
N-[3-(1,3-benzothiazol-2-yl)-5,6-dihydro-4H-thieno[2,3-c]pyrrol-2-yl]acetamide[no description available]low00benzothiazoles
ML355[no description available]low00benzothiazoles;
monomethoxybenzene;
phenols;
secondary amino compound;
substituted aniline;
sulfonamide		EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor;
platelet aggregation inhibitor
dehydroluciferin[no description available]low001,3-thiazolemonocarboxylic acid;
benzothiazoles;
biaryl;
phenols		animal metabolite;
luciferin
ConditionIndicatedRelationship StrengthStudiesTrials
Inflammation0low10
Innate Inflammatory Response0low10