1,3,5-triaminocyclohexane

Description

## 1,3,5-Triaminocyclohexane: A Versatile Building Block

1,3,5-Triaminocyclohexane (also known as **1,3,5-tris(aminomethyl)cyclohexane**, **TACH**, or **tach**) is an organic compound with the molecular formula C9H18N3. It's a **trifunctional amine** with three primary amine groups attached to a cyclohexane ring.

**Importance in Research:**

TACH is a versatile building block used in various research areas due to its unique properties:

* **Chelation:** It acts as a strong **chelating agent**, forming stable complexes with metal ions. This property makes it crucial for:
* **Catalysis:** TACH-metal complexes exhibit catalytic activity in various reactions, including organic synthesis and polymerization.
* **Material Science:** TACH-based metal complexes are used in the development of new materials with specific properties, such as luminescence, magnetism, and conductivity.

* **Ligand Synthesis:** TACH can be readily modified to generate various ligands with tailored properties. This allows for:
* **Coordination Chemistry:** TACH derivatives are used to study the coordination behavior of metal ions and design new coordination complexes.
* **Bioinorganic Chemistry:** TACH-based ligands are utilized in designing model systems for metalloenzymes and biological processes.

* **Drug Development:** TACH derivatives have shown promising potential in various therapeutic areas, including:
* **Antibacterial Agents:** Some TACH derivatives exhibit antibacterial activity against a broad range of bacteria.
* **Anticancer Agents:** TACH-based metal complexes have been investigated as potential anticancer drugs due to their ability to target and inhibit specific biological pathways.
* **Antiviral Agents:** TACH derivatives are being explored for their potential antiviral activity against emerging viruses.

* **Polymer Chemistry:** TACH is used as a monomer for the synthesis of polymers with specific properties, such as:
* **Polyamides:** TACH-based polyamides exhibit high thermal stability and mechanical strength.
* **Polyurethanes:** TACH-based polyurethanes are used in various applications, including foams, coatings, and adhesives.

**Overall, 1,3,5-triaminocyclohexane is a versatile building block with diverse applications in various research fields, contributing to the advancement of chemistry, materials science, and drug development.**

**Note:** It's important to be aware that TACH is a potentially toxic compound. Therefore, appropriate safety measures should be taken when handling it.

1,3,5-triaminocyclohexane: forms a complex with copper than can hydrolyze phosphoric esters; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]