Page last updated: 2024-12-05

1,2-dithiolane-4-carboxylic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1,2-dithiolane-4-carboxylic acid is a heterocyclic organic compound with the chemical formula C4H6O2S2. It's essentially a five-membered ring containing two sulfur atoms (dithiolane) and a carboxylic acid group.

**Importance in Research:**

1,2-dithiolane-4-carboxylic acid is not a well-known or commonly researched compound. Its importance, if any, would likely stem from its potential use as a building block or intermediate in synthesizing other compounds.

Here's why:

* **Sulfur-containing compounds:** The presence of sulfur in the molecule opens up possibilities for its use in the synthesis of compounds with sulfur-containing functionalities, which are relevant in various fields like:
* **Pharmaceuticals:** Many drugs contain sulfur, so 1,2-dithiolane-4-carboxylic acid might be explored as a starting point for synthesizing new drug candidates.
* **Agrochemicals:** Sulfur is also found in pesticides and herbicides.
* **Materials science:** Sulfur-containing compounds find use in polymers and other materials.
* **Carboxylic acid group:** The carboxylic acid group makes the molecule reactive and potentially useful for attaching to other molecules, creating new compounds with different properties.

However, without specific research indicating its importance, it's difficult to provide a definitive answer about its role in research.

**Important Note:** If you are researching this compound, make sure to consult relevant scientific literature and databases to find specific information about its synthesis, properties, and applications.

1,2-dithiolane-4-carboxylic acid: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID16682
CHEMBL ID3581910
CHEBI ID18091
SCHEMBL ID2796676
MeSH IDM0055270

Synonyms (30)

Synonym
1,2-dithiolane-4-carboxylic acid
CHEBI:18091
ph 800/21
brn 0112178
C01892
2224-02-4
asparagusic acid
arachidonic acid trifluoromethylketone
dithiolane-4-carboxylic acid
AKOS006277672
[1,2]dithiolane-4-carboxylic acid
vad3xv509r ,
unii-vad3xv509r
5-19-07-00224 (beilstein handbook reference)
CS-B0536
SCHEMBL2796676
CHEMBL3581910
DTXSID00176779
asparagusic acid [mi]
ph-800/21
1,2-dithiacyclopentane-4-carboxylic acid
HY-50730
Q312125
BS-16096
mfcd01729684
A901670
D82957
1,2-dithiolan-4-carbonsa currencyure
CAA22402
asparagusicacid
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (3)

ClassDescription
sulfur-containing carboxylic acidAny carboxylic acid having a sulfur substituent.
dithiolanecarboxylic acid
dithiolanes
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID1228660Inhibition of ACE (unknown origin) using 3-Hydroxybutylyl-Gly-Gly-Gly substrate assessed as reduction in 3-Hyroxybutylic acid generation incubated for 1 hr by colorimetric assay2015Journal of natural products, May-22, Volume: 78, Issue:5
Top-down Targeted Metabolomics Reveals a Sulfur-Containing Metabolite with Inhibitory Activity against Angiotensin-Converting Enzyme in Asparagus officinalis.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's9 (81.82)24.3611
2020's1 (9.09)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 13.15

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index13.15 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index5.63 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (13.15)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews3 (27.27%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (72.73%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]