1,2-dihydroxy-5,6-dimethyl-3,4-epoxy-1,2,3,4-tetrahydrochrysene

Description

The compound **1,2-dihydroxy-5,6-dimethyl-3,4-epoxy-1,2,3,4-tetrahydrochrysene** is a derivative of chrysene, a polycyclic aromatic hydrocarbon (PAH). This specific derivative exhibits unique structural features, including:

* **Two hydroxyl groups (OH)** at positions 1 and 2.
* **Two methyl groups (CH3)** at positions 5 and 6.
* **An epoxide ring (O)** bridging carbons 3 and 4.

These structural features are important because they confer specific properties to the molecule, including:

* **Potential biological activity**: The hydroxyl groups are known to participate in hydrogen bonding, which is important for interactions with biological molecules. The epoxide ring can potentially undergo ring-opening reactions, which can lead to the formation of reactive intermediates that can interact with cellular components.
* **Chemical reactivity**: The epoxide ring is a reactive functional group that can be exploited for synthetic purposes. This reactivity can be utilized in various chemical reactions, such as nucleophilic ring-opening reactions and oxidation reactions.
* **Optical properties**: The presence of the aromatic ring system and the specific substituents can influence the optical properties of the molecule, such as its absorbance and fluorescence.

**Research Importance:**

This compound and its derivatives are of interest to researchers in various fields, including:

* **Cancer research**: PAHs, including chrysene derivatives, have been implicated in cancer development. Understanding the biological activity of these compounds is crucial for developing potential cancer therapies.
* **Environmental chemistry**: PAHs are prevalent environmental pollutants. Studying the fate and transformation of these compounds in the environment is essential for assessing their impact on human health and ecosystems.
* **Materials science**: The unique structural features of this compound could potentially be utilized for developing new materials with specific properties, such as optical materials or catalysts.

**In summary**, 1,2-dihydroxy-5,6-dimethyl-3,4-epoxy-1,2,3,4-tetrahydrochrysene is a complex molecule with a unique combination of structural features that makes it interesting for research in various fields, particularly those related to cancer, environmental science, and materials science. Further research on this compound and its derivatives could lead to valuable discoveries and advancements in these fields.

1,2-dihydroxy-5,6-dimethyl-3,4-epoxy-1,2,3,4-tetrahydrochrysene: structure given in first source; RN given refers to ((1alpha,2beta,2abeta,3abeta)-(+-))-isomer; RN for cpd without isomeric designation not available 9/92 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]