## 1,2-Dibenzoylethene: A Versatile Building Block for Research
1,2-Dibenzoylethene, also known as trans-dibenzoylethylene, is an organic compound with the chemical formula C16H12O2. It is a symmetrical molecule consisting of two benzoyl groups (C6H5CO) connected by a double bond.
**Importance in Research:**
1,2-Dibenzoylethene serves as a valuable building block in various research areas due to its unique chemical and physical properties:
* **Photochemistry:** It exhibits photochromism, meaning it changes color upon exposure to light. This property makes it interesting for potential applications in optical memory, sensors, and other light-sensitive materials.
* **Organic Synthesis:** It acts as a versatile precursor in the synthesis of various complex organic molecules. Its reactive double bond can participate in reactions like Diels-Alder, Wittig, and Grignard, enabling the formation of new functional groups.
* **Materials Science:** It can be used in the development of organic semiconductors, organic light-emitting diodes (OLEDs), and other optoelectronic materials.
* **Biochemistry:** Its photochromic properties make it useful for studying biological processes like protein folding and drug delivery.
* **Catalysis:** It can be employed as a photocatalyst in various organic reactions, due to its ability to absorb light and generate reactive species.
**Applications:**
* **Photochromic Devices:** Its photochromic properties can be utilized in sunglasses, displays, and other devices that change color under different light conditions.
* **Organic Electronics:** Its unique electronic properties make it a promising component in organic transistors, solar cells, and other electronic devices.
* **Medicinal Chemistry:** It can be incorporated into drugs to improve their absorption, distribution, and bioavailability.
**Conclusion:**
1,2-Dibenzoylethene is a fascinating molecule with diverse applications in various research fields. Its unique photochromic, synthetic, and electronic properties make it a valuable tool for exploring new materials, understanding biological processes, and developing innovative technologies.
1,2-dibenzoylethene: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 735960 |
| SCHEMBL ID | 2954318 |
| SCHEMBL ID | 2954324 |
| MeSH ID | M0404496 |
| Synonym |
|---|
| HMS1757J15 |
| nsc-1983 |
| trans-1,4-dione |
| nsc1983 |
| trans-1,2-(dibenzoyl)ethylene |
| 959-28-4 |
| 2-butene-1, 1,4-diphenyl-, (e)- |
| 2-butene-1,4-dione, 1,4-diphenyl- |
| ethylene, 1,2-dibenzoyl- |
| 2-butene-1,4-dione, 1,4-diphenyl-, (e)- |
| trans-1,2-dibenzoylethylene |
| nsc28072 |
| usaf nd-57 |
| 1,2-dibenzoylethene |
| 4070-75-1 |
| 1,2-dibenzoylethylene |
| dibenzoylethylene |
| 2-butene-1, 1,4-diphenyl- |
| wln: rv1u1vr |
| ethylene,2-dibenzoyl- |
| nsc-28072 |
| einecs 223-780-6 |
| 1,4-diphenylbut-2-ene-1,4-dione |
| brn 1871333 |
| nsc 28072 |
| AE-848/01504029 |
| (e)-1,4-diphenylbut-2-ene-1,4-dione |
| 1,4-diphenyl-2-butene-1,4-dione |
| trans-1,4-diphenyl-2-butene-1,4-dione, 96% |
| D2185 |
| trans-diphenacylidene |
| trans-1,4-diphenyl-2-butene-1,4-dione |
| AKOS001027092 |
| (e)-1,4-diphenyl-but-2-ene-1,4-dione |
| 0-07-00-00812 (beilstein handbook reference) |
| nsc 1983 |
| (e)-1,4-diphenyl-2-butene-1,4-dione |
| 2-butene-1,4-dione, 1,4-diphenyl-, (2e)- |
| einecs 213-498-1 |
| (2e)-1,4-diphenylbut-2-ene-1,4-dione |
| 6N-723 |
| DTXSID0063284 |
| SCHEMBL2954318 |
| SCHEMBL2954324 |
| (2e)-1,4-diphenyl-2-butene-1,4-dione # |
| WYCXGQSQHAXLPK-VAWYXSNFSA-N |
| 2-butene-1,4-dione,1,4-diphenyl-,(2e)- |
| 2-butene-1,4-dione,1,4-diphenyl- |
| mfcd00003083 |
| CS-0204677 |
| Z56756394 |
| trans-1.4-diphenyl-2-butene-1.4-dione |
| D90008 |
| 1,4-diphenyl-but-2-ene-1,4-dione |
| DTXSID70883625 |
| STARBLD0000826 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3 | High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.87) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||