Compounds > 1,2-bis(4-(n-butyl)phenylazo-4'-phenylbutyroyl)phosphatidylcholine
Page last updated: 2024-12-10

1,2-bis(4-(n-butyl)phenylazo-4'-phenylbutyroyl)phosphatidylcholine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

You're describing a complex molecule with a very specific structure and purpose. Let's break it down:

**1,2-bis(4-(n-butyl)phenylazo-4'-phenylbutyroyl)phosphatidylcholine:**

* **Phosphatidylcholine:** This is a type of phospholipid, which are the main components of cell membranes. They have a hydrophilic (water-loving) head and a hydrophobic (water-repelling) tail.
* **1,2-bis...:** This indicates that two identical groups are attached to the phosphatidylcholine molecule.
* **4-(n-butyl)phenylazo-4'-phenylbutyroyl:** This is a long, complex group with the following parts:
* **n-butyl:** A straight-chain hydrocarbon group (CH3CH2CH2CH3).
* **phenylazo:** A nitrogen-containing aromatic ring group.
* **phenylbutyroyl:** A combination of a phenyl ring (C6H5) and a butyroyl group (CH3CH2CH2CO).
* **4'-phenyl:** Another phenyl ring attached to the butyroyl group.

**Why is this molecule important for research?**

This specific molecule, **1,2-bis(4-(n-butyl)phenylazo-4'-phenylbutyroyl)phosphatidylcholine**, likely acts as a **photoactive lipid**. This means it absorbs light and undergoes a change in its properties.

Here's how it could be useful in research:

* **Membrane studies:** By incorporating this molecule into artificial membranes (like liposomes), researchers can study how light affects the structure and function of cell membranes.
* **Drug delivery:** The photoactive properties could be used to trigger the release of drugs or other molecules encapsulated within liposomes when exposed to specific wavelengths of light.
* **Bioimaging:** The molecule's fluorescence properties could be used to track and visualize cell membranes or specific compartments within cells.
* **Photodynamic therapy:** The molecule could potentially be used for photodynamic therapy, a treatment that uses light to activate a drug and destroy cancer cells.

**Important Note:** It's crucial to remember that this molecule is likely a specific research tool developed within a particular laboratory. It's unlikely to be a widely used compound in the general scientific community.

**To understand the specific research applications and significance of this molecule, you'd need more context about the research it was developed for.**

1,2-bis(4-(n-butyl)phenylazo-4'-phenylbutyroyl)phosphatidylcholine: forms stable bilayer vesicles; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID3081021
MeSH IDM0152530

Synonyms (5)

Synonym
3,5,9-trioxa-4-phosphatridecan-1-aminium, 13-(4-((4-butylphenyl)azo)phenyl)-7-(4-(4-((4-butylphenyl)azo)phenyl)-1-oxobutoxy)-4-hydroxy-n,n,n-trimethyl-10-oxo-, hydroxide, inner salt, 4-oxide, (r)-
112791-47-6
1,2-bis(4-(n-butyl)phenylazo-4'-phenylbutyroyl)phosphatidylcholine
bis-azo pc
[(2r)-2,3-bis[4-[4-[(4-butylphenyl)diazenyl]phenyl]butanoyloxy]propyl] 2-(trimethylazaniumyl)ethyl phosphate
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (33.33)18.7374
1990's4 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.67

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.67 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.62 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.67)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
erythrosine
Fluoresceins: A family of spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one derivatives. These are used as dyes, as indicators for various metals, and as fluorescent labels in immunoassays.		2.6730
1,2-dipalmitoylphosphatidylcholine
1,2-Dipalmitoylphosphatidylcholine: Synthetic phospholipid used in liposomes and lipid bilayers to study biological membranes. It is also a major constituent of PULMONARY SURFACTANTS.		2.8940
copper sulfate
Copper Sulfate: A sulfate salt of copper. It is a potent emetic and is used as an antidote for poisoning by phosphorus. It also can be used to prevent the growth of algae.. copper(II) sulfate : A metal sulfate compound having copper(2+) as the metal ion.		1.9810metal sulfateemetic;
fertilizer;
sensitiser
fluorexon
fluorexon: structure		2.6730xanthene dyefluorochrome
1,2-distearoyllecithin
[no description available]		1.9710
5-doxylstearate
[no description available]		1.9710aminoxyls
diphenylhexatriene
Diphenylhexatriene: A fluorescent compound that emits light only in specific configurations in certain lipid media. It is used as a tool in the study of membrane lipids.		1.9710alkatrienefluorochrome
phosphatidylcholines
Phosphatidylcholines: Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.		3.23601,2-diacyl-sn-glycero-3-phosphocholine
chlorophyll a
Chlorophyll: Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organisms.. chlorophyll : A family of magnesium porphyrins, defined by the presence of a fifth ring beyond the four pyrrole-like rings. The rings can have various side chains which usually include a long phytol chain.		1.9710chlorophyll;
methyl ester		cofactor
ascorbic acid
Ascorbic Acid: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.. L-ascorbic acid : The L-enantiomer of ascorbic acid and conjugate acid of L-ascorbate.. L-ascorbate : The L-enantiomer of ascorbate and conjugate base of L-ascorbic acid, arising from selective deprotonation of the 3-hydroxy group. Required for a range of essential metabolic reactions in all animals and plants.. vitamin C : Any member of a group of vitamers that belong to the chemical structural class called butenolides that exhibit biological activity against vitamin C deficiency in animals. The vitamers include L-ascorbic acid and its salt, ionized and oxidized forms.		1.9810ascorbic acid;
vitamin C		coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent
pheophytin a
pheophytin a: structure given in first source; RN given refers to (3S-(3alpha(2E,7S*,11S*),4beta,21beta))-isomer		1.9710
ConditionIndicatedRelationship StrengthStudiesTrials