Compounds > 1,2,6-tri-o-galloyl-beta-d-glucopyranose
Page last updated: 2024-12-08

1,2,6-tri-o-galloyl-beta-d-glucopyranose

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

## 1,2,6-tri-O-galloyl-beta-D-glucopyranose: A Powerful Antioxidant

**1,2,6-tri-O-galloyl-beta-D-glucopyranose** is a complex polyphenol molecule found naturally in various plants, particularly in the seeds of the **tea plant (Camellia sinensis)**.

**Structure and Composition:**

* **Galloyl groups:** The molecule is composed of a beta-D-glucopyranose core, which is a sugar molecule, and three galloyl groups attached to it at positions 1, 2, and 6. Galloyl groups are esters of gallic acid, a powerful antioxidant.
* **Molecular formula:** C27H22O18

**Importance in Research:**

1,2,6-tri-O-galloyl-beta-D-glucopyranose has attracted significant interest in research due to its potent **antioxidant properties** and potential for various health benefits:

* **Antioxidant Activity:** The galloyl groups are responsible for its strong antioxidant activity. They can effectively scavenge free radicals, protecting cells from oxidative stress and damage. This is crucial for preventing various diseases related to oxidative stress, like cancer, cardiovascular disease, and neurodegenerative disorders.
* **Anti-inflammatory Effects:** Studies suggest that this compound possesses anti-inflammatory properties, which may contribute to its potential therapeutic benefits.
* **Anti-diabetic Effects:** Research indicates that 1,2,6-tri-O-galloyl-beta-D-glucopyranose might help regulate blood sugar levels and potentially improve insulin sensitivity, making it relevant for diabetes research.
* **Anti-microbial Activity:** Some studies suggest that this compound could have anti-microbial effects, potentially combating certain bacterial and fungal infections.

**Research Applications:**

* **Developing novel therapeutic agents:** Scientists are exploring the potential of this compound for developing new drugs or supplements to combat diseases like cancer, diabetes, and inflammatory conditions.
* **Improving food safety:** Research is exploring its use as a natural antioxidant to extend the shelf life of food products and improve their nutritional value.
* **Understanding the role of polyphenols in human health:** Studying this compound helps scientists understand the complex mechanisms of polyphenols and their impact on human health.

**Current Research:**

Ongoing research is focused on:

* **Understanding the specific molecular mechanisms responsible for its diverse biological activities.**
* **Developing efficient and sustainable extraction methods for isolating this compound from natural sources.**
* **Developing safe and effective formulations for its use in various applications.**

**Conclusion:**

1,2,6-tri-O-galloyl-beta-D-glucopyranose holds significant promise for various biomedical and technological applications due to its potent antioxidant properties and potential therapeutic benefits. Ongoing research continues to unravel its potential and explore its applications in improving human health and well-being.

1,2,6-tri-O-galloyl-beta-D-glucopyranose: from Terminalia chebula fruits, effective against multidrug-resistant uropathogens; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

1,2,6-tris-O-galloyl-beta-D-glucose : A galloyl-beta-D-glucose compound having the galloyl groups in the 1-, 2- and 6-positions. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

FloraRankFlora DefinitionFamilyFamily Definition
TerminaliagenusA plant genus of the family COMBRETACEAE. Members contain arjunin, an ellagitannin (TANNINS).[MeSH]CombretaceaeA plant family of the order Myrtales, subclass Rosidae, class Magnoliopsida. They are mostly trees and shrubs growing in warm areas.[MeSH]
Terminalia chebulaspecies[no description available]CombretaceaeA plant family of the order Myrtales, subclass Rosidae, class Magnoliopsida. They are mostly trees and shrubs growing in warm areas.[MeSH]

Cross-References

ID SourceID
PubMed CID440308
CHEMBL ID447974
CHEBI ID27395
SCHEMBL ID2370653
MeSH IDM0591768

Synonyms (26)

Synonym
79886-49-0
C04360 ,
1-o,2-o,6-o-trigalloyl-beta-d-glucose
1,2,6-trigalloylglucose
[(2r,3s,4s,5r,6s)-3,4-dihydroxy-5,6-bis[(3,4,5-trihydroxybenzoyl)oxy]tetrahydropyran-2-yl]methyl 3,4,5-trihydroxybenzoate
1,2,6-tri-o-gallose-beta-d-glucopyranose
1,2,6-trikis-o-galloyl-beta-d-glucose
bdbm50250504
CHEBI:27395 ,
1,2,6-tris-o-galloyl-beta-d-glucose
1,2,6-tris-o-(3,4,5-trihydroxybenzoyl)-beta-d-glucopyranose
CHEMBL447974 ,
beta-d-glucopyranose, 1,2,6-tris(3,4,5-trihydroxybenzoate)
1,2,6-trigalloyl glucose
SCHEMBL2370653
ncgc00384822-01![(2r,3s,4s,5r,6s)-3,4-dihydroxy-5,6-bis[(3,4,5-trihydroxybenzoyl)oxy]oxan-2-yl]methyl 3,4,5-trihydroxybenzoate
Q4545648
DTXSID901000816
1,2,6-tri-o-galloylglucose
PD119278
1,2,6-tri-o-galloyl-beta-d-glucopyranose
1,2,6-tri-galloyl-beta-d-glucose
[4,5-dihydroxy-2-(3,4,5-trihydroxybenzoyl)oxy-6-[(3,4,5-trihydroxybenzoyl)oxymethyl]oxan-3-yl] 3,4,5-trihydroxybenzoate
CS-0645777
1,2,6-tri-o-galloyl-|a-d-glucose
HY-N11285
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (2)

ClassDescription
galloyl beta-D-glucoseA class of beta-D-glucose compounds having an unspecified number of O-galloyl groups in undeined positions.
gallate esterA benzoate ester that is any ester resulting from the formal condensation of the carboxy group of gallic acid (3,4,5-trihydroxybenzoic acid) with an alcoholic or phenolic hydroxy group.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (2)

PathwayProteinsCompounds
superpathway of hydrolyzable tannin biosynthesis030
pentagalloylglucose biosynthesis012

Protein Targets (2)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Genome polyprotein IC50 (µMol)1.89000.70001.95673.8000AID241704
Squalene monooxygenase Rattus norvegicus (Norway rat)IC50 (µMol)0.63000.06102.344610.0000AID357310
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (14)

Assay IDTitleYearJournalArticle
AID1778694Antibacterial activity against Escherichia coli DSM 1116 assessed as growth inhibition by serial dilution assay2021Journal of natural products, 05-28, Volume: 84, Issue:5
Cytotoxic Compounds from the Stem Bark of Two subsp. of
AID362725Inhibition of Escherichia coli RNase H by FRET assay2008Journal of natural products, Sep, Volume: 71, Issue:9
HIV-1 ribonuclease H inhibitory phenolic glycosides from Eugenia hyemalis.
AID358167Cytotoxicity against human A549 cells by tetrazolium salt-based colorimetric assay1992Journal of natural products, Aug, Volume: 55, Issue:8
Antitumor agents, 129. Tannins and related compounds as selective cytotoxic agents.
AID1778697Antibacterial activity against Mycobacterium smegmatis DSM ATCC 700084 assessed as growth inhibition by serial dilution assay2021Journal of natural products, 05-28, Volume: 84, Issue:5
Cytotoxic Compounds from the Stem Bark of Two subsp. of
AID241704Inhibitory activity against Hepatitis C virus NS3 protease by ELISA2004Bioorganic & medicinal chemistry letters, Dec-20, Volume: 14, Issue:24
Antiviral compounds from traditional Chinese medicines Galla Chinese as inhibitors of HCV NS3 protease.
AID358165Cytotoxicity against human PRMI7951 cells by tetrazolium salt-based colorimetric assay1992Journal of natural products, Aug, Volume: 55, Issue:8
Antitumor agents, 129. Tannins and related compounds as selective cytotoxic agents.
AID362726Inhibition of human RNase H by FRET assay2008Journal of natural products, Sep, Volume: 71, Issue:9
HIV-1 ribonuclease H inhibitory phenolic glycosides from Eugenia hyemalis.
AID357310Inhibition of rat squalene epoxidase2001Journal of natural products, Aug, Volume: 64, Issue:8
Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase.
AID358166Cytotoxicity against human KB cells by tetrazolium salt-based colorimetric assay1992Journal of natural products, Aug, Volume: 55, Issue:8
Antitumor agents, 129. Tannins and related compounds as selective cytotoxic agents.
AID362724Inhibition of HIV2 RNase H by FRET assay2008Journal of natural products, Sep, Volume: 71, Issue:9
HIV-1 ribonuclease H inhibitory phenolic glycosides from Eugenia hyemalis.
AID362723Inhibition of HIV1 RNase H by FRET assay2008Journal of natural products, Sep, Volume: 71, Issue:9
HIV-1 ribonuclease H inhibitory phenolic glycosides from Eugenia hyemalis.
AID358169Cytotoxicity against human TE671 cells by tetrazolium salt-based colorimetric assay1992Journal of natural products, Aug, Volume: 55, Issue:8
Antitumor agents, 129. Tannins and related compounds as selective cytotoxic agents.
AID399391Inhibition of HIV1 recombinant integrase expressed in Escherichia coli1998Journal of natural products, Jan, Volume: 61, Issue:1
A new flavonol glycoside gallate ester from Acer okamotoanum and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase.
AID358168Cytotoxicity against human HCT8 cells by tetrazolium salt-based colorimetric assay1992Journal of natural products, Aug, Volume: 55, Issue:8
Antitumor agents, 129. Tannins and related compounds as selective cytotoxic agents.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.30

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.30 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.79 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.30)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
gallic acid
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.		210trihydroxybenzoic acidantineoplastic agent;
antioxidant;
apoptosis inducer;
astringent;
cyclooxygenase 2 inhibitor;
EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor;
geroprotector;
human xenobiotic metabolite;
plant metabolite
gentamicin
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.		2.1510
trimethoprim
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.. trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.		2.1510aminopyrimidine;
methoxybenzenes		antibacterial drug;
diuretic;
drug allergen;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor;
environmental contaminant;
xenobiotic
arginine
Arginine: An essential amino acid that is physiologically active in the L-form.. arginine : An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group.		2.110arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
methyl gallate
methyl gallate: has both immunosuppressive and phytogenic antineoplastic activities; isolated from Acer saccharinum. methyl 3,4,5-trihydroxybenzoate : A gallate ester obtained by the formal condensation of gallic acid with methanol. It exhibits anti-oxidant, anti-tumor, anti-microbial and anti-inflammatory properties.		1.9910gallate esteranti-inflammatory agent;
antioxidant;
plant metabolite
catechin
Catechin: An antioxidant flavonoid, occurring especially in woody plants as both (+)-catechin and (-)-epicatechin (cis) forms.. catechin : Members of the class of hydroxyflavan that have a flavan-3-ol skeleton and its substituted derivatives.. rac-catechin : A racemate comprising equimolar amounts of (+)- and (-)-catechin. (+)-catechin : The (+)-enantiomer of catechin and a polyphenolic antioxidant plant metabolite.		1.9810catechinantioxidant;
plant metabolite
ethyl gallate
ethyl gallate: used with osmium in procedure for mapping neuronal pathways. ethyl gallate : A gallate ester obtained by the formal condensation of gallic acid with ethanol.		210gallate esterplant metabolite
lauryl gallate
[no description available]		210gallate ester
octyl gallate
[no description available]		210gallate esterfood antioxidant;
hypoglycemic agent;
plant metabolite
epigallocatechin gallate
epigallocatechin gallate: a steroid 5alpha-reductase inhibitor and antimutagen in green tea (Camellia sinensis). (-)-epigallocatechin 3-gallate : A gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin.		210flavans;
gallate ester;
polyphenol		antineoplastic agent;
antioxidant;
apoptosis inducer;
geroprotector;
Hsp90 inhibitor;
neuroprotective agent;
plant metabolite
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose
pentagalloylglucose: pentahydroxy gallic acid ester of glucose; a phytogenic antineoplastic agent and antibacterial agent. 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose : A galloyl-beta-D-glucose compound having five galloyl groups in the 1-, 2-, 3-, 4- and 6-positions.		2.9140gallate ester;
galloyl beta-D-glucose		anti-inflammatory agent;
antineoplastic agent;
geroprotector;
hepatoprotective agent;
plant metabolite;
radiation protective agent;
radical scavenger
epicatechin
(-)-epicatechin : A catechin with (2R,3R)-configuration.		1.9810catechin;
polyphenol		antioxidant
1,2,3,6-tetragalloylglucose
1,2,3,6-tetragalloylglucose: structure given in first source. 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose : A galloyl-beta-D-glucose compound having four galloyl groups in the 1-, 2-, 3- and 6-positions.		2.4420gallate ester;
galloyl beta-D-glucose
strictinin
strictinin: antioxidant from green tea leaves (Camellia sinensis L.); structure in first source		1.9810
corilagin
corilagin: isolated from Geranii herba. corilagin : An ellagitannin with a hexahydroxydiphenoyl group bridging over the 3-O and 6-O of the glucose core.		2.3920ellagitannin;
gallate ester		antihypertensive agent;
antioxidant;
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor;
non-steroidal anti-inflammatory drug
casuarictin
sanguiin H 11: regulates chemotaxis of neutrophil; from plant, Sanguisorba officinalis; structure in first source		2.3920tannin
epicatechin gallate
epicatechin gallate: a steroid 5alpha-reductase inhibitor; RN given refers to the (cis)-isomer; structure given in first source; isolated from green tea. (-)-epicatechin-3-O-gallate : A gallate ester obtained by formal condensation of the carboxy group of gallic acid with the (3R)-hydroxy group of epicatechin. A natural product found in Parapiptadenia rigida.		1.9810catechin;
gallate ester;
polyphenol		EC 3.2.1.1 (alpha-amylase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
metabolite
procyanidin b2
procyanidin B2 : A proanthocyanidin consisting of two molecules of (-)-epicatechin joined by a bond between positions 4 and 8' in a beta-configuration. Procyanidin B2 can be found in Cinchona pubescens (Chinchona, in the rind, bark and cortex), in Cinnamomum verum (Ceylon cinnamon, in the rind, bark and cortex), in Crataegus monogyna (Common hawthorn, in the flower and blossom), in Uncaria guianensis (Cat's claw, in the root), in Vitis vinifera (Common grape vine, in the leaf), in Litchi chinensis (litchi, in the pericarp), in the apple, in Ecdysanthera utilis and in red wine.		1.9810biflavonoid;
hydroxyflavan;
polyphenol;
proanthocyanidin		antioxidant;
metabolite
procyanidin b2-3,3'-di-o-gallate
procyanidin B2-3,3'-di-O-gallate: structure in first source		2.3920flavonoid oligomer
proanthocyanidin a2
procyanidin A2: structure in first source. proanthocyanidin A2 : A proanthocyanidin obtained by the condensation of (-)-epicatechin units.		1.9810hydroxyflavan;
proanthocyanidin		angiogenesis modulating agent;
anti-HIV agent;
antioxidant;
metabolite
3,4,5-tri-o-galloylquinic acid
3,4,5-tri-O-galloylquinic acid: DNA polymerase inhibitor; structure given in first source		1.9810
arginine beta-naphthylamide
arginine beta-naphthylamide: RN given refers to (S)-isomer. L-arginine 2-naphthylamide : An L-arginine derivative that is the amide obtained by formal condensation of the carboxy group of L-arginine with the amino group of 2-naphthylamine.		2.110amino acid amide;
L-arginine derivative;
N-(2-naphthyl)carboxamide		chromogenic compound
procyanidin C1
procyanidin trimer C1: a flavonoid found in multiple plant sources including grape, apple, and cacao, which has antioxidant and anti-inflammatory properties. procyanidin C1 : A proanthocyanidin consisting of three (-)-epicatechin units joined by two successive (4beta->8)-linkages.		1.9810hydroxyflavan;
polyphenol;
proanthocyanidin		anti-inflammatory agent;
antioxidant;
EC 1.17.3.2 (xanthine oxidase) inhibitor;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
lipoxygenase inhibitor;
metabolite
theasinensin a
theasinensin A: a tea polyphenol formed from (-)-epigallocatechin gallate, suppresses antibiotic resistance of methicillin-resistant Staphylococcus aureus. theasinensin A : A biflavonoid that is obtained by coupling of two molecules of (-)-epigallocatechin 3-gallate resulting in a bond between positions C-2 of the hydroxyphenyl ring. It is a natural product found in oolong tea.		210biflavonoid;
gallate ester;
proanthocyanidin		anti-inflammatory agent;
anticoronaviral agent;
apoptosis inducer;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
hepatoprotective agent;
hypoglycemic agent;
melanin synthesis inhibitor;
plant metabolite
Chebulagic acid
[no description available]		2.3920tannin
eugeniin
eugeniin: structure in first source. eugeniin : An ellagitannin isolated from the dried flower buds of Eugenia caryophyllata. It exhibits alpha-glucosidase inhibitory activity and antiviral activity against acyclovir and phosphonoacetic acid (PAA)-resistant herpes simplex virus type 1 (HSV-1) as well as the wild-type HSV-1.		2.3920beta-D-glucoside;
ellagitannin;
gallate ester;
lactone		anti-HSV-1 agent;
antifungal agent;
antineoplastic agent;
EC 3.2.1.20 (alpha-glucosidase) inhibitor;
metabolite
Pedunculagin
pedunculagin: from the walnut (Juglans regia) pellicle		2.3920tannin
phenylalanine arginine beta-naphthylamide
phenylalanine arginine beta-naphthylamide: a drug efflux pump inhibitor; structure in first source		2.110peptide
dactinomycin
Dactinomycin: A compound composed of a two CYCLIC PEPTIDES attached to a phenoxazine that is derived from STREPTOMYCES parvullus. It binds to DNA and inhibits RNA synthesis (transcription), with chain elongation more sensitive than initiation, termination, or release. As a result of impaired mRNA production, protein synthesis also declines after dactinomycin therapy. (From AMA Drug Evaluations Annual, 1993, p2015)		1.9810actinomycinmutagen
cinnamtannin b-1
cinnamtannin B-1: COX2 Inhibitor from bay wood and bark of Cinnamomum cassia; structure in second source. cinnamtannin B-1 : A proanthocyanidin found in Cinnamomum cassia and Cinnamomum zeylanicum.		1.9810proanthocyanidincyclooxygenase 2 inhibitor;
plant metabolite
squalene
Addavax: an oil-water nanoemulsion and adjuvant containing squalene, Tween 80, and sorbitane trioleate		210triterpenehuman metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
Geraniin
[no description available]		2.3920tannin
quercitrin
[no description available]		2.4220alpha-L-rhamnoside;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		antileishmanial agent;
antioxidant;
EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.14.18.1 (tyrosinase) inhibitor;
plant metabolite
hyperoside
quercetin 3-O-beta-D-galactopyranoside : A quercetin O-glycoside that is quercetin with a beta-D-galactosyl residue attached at position 3. Isolated from Artemisia capillaris, it exhibits hepatoprotective activity.		1.9910beta-D-galactoside;
monosaccharide derivative;
quercetin O-glycoside;
tetrahydroxyflavone		hepatoprotective agent;
plant metabolite
ellagic acid
[no description available]		210catechols;
cyclic ketone;
lactone;
organic heterotetracyclic compound;
polyphenol		antioxidant;
EC 1.14.18.1 (tyrosinase) inhibitor;
EC 2.3.1.5 (arylamine N-acetyltransferase) inhibitor;
EC 2.4.1.1 (glycogen phosphorylase) inhibitor;
EC 2.5.1.18 (glutathione transferase) inhibitor;
EC 2.7.1.127 (inositol-trisphosphate 3-kinase) inhibitor;
EC 2.7.1.151 (inositol-polyphosphate multikinase) inhibitor;
EC 2.7.4.6 (nucleoside-diphosphate kinase) inhibitor;
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
food additive;
fungal metabolite;
geroprotector;
plant metabolite;
skin lightening agent
kaempferol 3-o-rhamnoside
kaempferol 3-O-rhamnoside: from apple (Malus domestica) leaves; structure in first source. afzelin : A glycosyloxyflavone that is kaempferol attached to an alpha-L-rhamnosyl residue at position 3 via a glycosidic linkage.		1.9910glycosyloxyflavone;
monosaccharide derivative;
trihydroxyflavone		anti-inflammatory agent;
antibacterial agent;
plant metabolite
2''-galloylhyperin
2''-galloylhyperin: isolated from Pyrola calliantha		1.9910flavonoids;
glycoside
furosin
furosin: an ellagitannin from extract of leaves & stems of Phyllanthus sellowianus; structure given in first source		2.3920
ConditionIndicatedRelationship StrengthStudiesTrials
Cancer of Prostate
[description not available]		02.1310
Prostatic Neoplasms
Tumors or cancer of the PROSTATE.		02.1310