Page last updated: 2024-12-08

1,10-phenanthroline-platinum(ii)-ethylenediamine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

You're asking about a compound that's a bit of a mouthful, so let's break it down:

**1,10-Phenanthroline-platinum(II)-ethylenediamine**

* **1,10-Phenanthroline:** This is a heterocyclic organic molecule with a nitrogen-containing structure. It has a strong tendency to bind to metal ions.
* **Platinum(II):** This refers to the platinum atom with a +2 charge.
* **Ethylenediamine:** This is a small organic molecule with two amine groups. It's also a good ligand (a molecule that binds to a metal ion).

**Structure:**

The full compound is a coordination complex. This means the platinum(II) ion is surrounded by ligands. In this case, it's likely that the platinum(II) ion is bound to two molecules of 1,10-phenanthroline and one molecule of ethylenediamine.

**Importance in Research:**

This specific compound, while interesting, might not be particularly well-studied or widely known. However, the components (platinum, 1,10-phenanthroline, and ethylenediamine) are all important in research:

* **Platinum:** Platinum-based complexes are known for their anticancer activity. Cisplatin, a platinum-based drug, is a common chemotherapy agent.
* **1,10-Phenanthroline:** This molecule is used in various applications, including:
* **Luminescence:** It can form luminescent complexes with metal ions, making it useful in analytical chemistry and material science.
* **Catalysis:** It can act as a ligand in catalysts for various reactions.
* **Ethylenediamine:** This is a common ligand in coordination chemistry. It helps to stabilize metal complexes and can influence their reactivity.

**Research Significance:**

The combination of these components might be explored in research for:

* **Developing new anticancer agents:** By varying the ligands around platinum, researchers can explore different properties and potentially enhance the effectiveness of platinum-based chemotherapy.
* **Studying the interaction of platinum complexes with DNA:** Understanding how platinum complexes interact with DNA is crucial to understanding their anticancer activity.
* **Creating new luminescent materials:** The combination of phenanthroline and platinum might lead to the development of novel materials for optical applications.

**Overall:**

While the specific compound you mentioned might not be widely researched, the individual components are essential in various scientific fields, particularly in medicine, chemistry, and materials science. The potential combinations of these components offer researchers avenues to explore new materials and therapies.

1,10-phenanthroline-platinum(II)-ethylenediamine: forms crystalline product with 3'-CMP; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID171377
MeSH IDM0122637

Synonyms (6)

Synonym
1,10-phenanthroline-platinum(ii)-ethylenediamine
1,10-phenanthrolineethylenediammineplatinum(ii)
platinum(2+), (1,2-ethanediamine-n,n')(1,10-phenanthroline-n1,n10)-, (sp-4-2)-
platinum(ii), ethylenediammine(1,10-phenathroline)-
54831-91-3
DTXSID90203326
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (40.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's6 (60.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.96

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.96 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.96)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]