Compounds > 1,10-bis(carboxymethylthiodecane)
Page last updated: 2024-12-08

1,10-bis(carboxymethylthiodecane)

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

## 1,10-Bis(carboxymethylthiodecane)

1,10-Bis(carboxymethylthiodecane) is a **synthetic molecule** with the chemical formula C16H30O4S2. It's a **long-chain dicarboxylic acid** with two carboxymethylthio groups attached at the ends of a ten-carbon decane chain.

**Importance in Research:**

This molecule is primarily used in research for its **potential applications in: **

* **Materials Science:**
* **Self-assembly:** It can self-assemble into **ordered structures** due to its long alkyl chain and polar carboxylic acid groups. This allows for the creation of **novel materials** with unique properties, like **nanofibers**, **thin films**, and **supramolecular assemblies**. These materials could find use in various applications, including **electronics**, **catalysis**, and **biomedicine**.
* **Biomedical Research:**
* **Drug delivery:** The molecule's **hydrophobic chain** could potentially be used to **encapsulate hydrophobic drugs** and its **carboxylic acid groups** could be modified for **targeted drug delivery**.
* **Biocompatible materials:** The molecule's **biocompatibility** makes it a potential candidate for use in **biomedical implants**, **tissue engineering**, and **drug delivery systems**.

**Current Research:**

There is ongoing research on the synthesis, characterization, and potential applications of 1,10-Bis(carboxymethylthiodecane). Researchers are exploring its self-assembly properties, its ability to form **nanostructures**, and its potential as a **biocompatible material**.

**Overall:**

1,10-Bis(carboxymethylthiodecane) is a promising molecule with potential applications in various research fields. Its unique properties and ability to self-assemble make it a versatile building block for creating new materials and exploring new technologies.

**Note:** While there is ongoing research, it is important to understand that this molecule is still in the **early stages of development** and its full potential is yet to be realized.

1,10-bis(carboxymethylthiodecane): structure given in first source; alkylthio dicarboxylic acid; non-beta-oxidizable & non-omega-oxidizable [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID161757
SCHEMBL ID5597990
MeSH IDM0171965

Synonyms (10)

Synonym
bcmtd
32827-49-9
2-[10-(carboxymethylsulfanyl)decylsulfanyl]acetic acid
3-thiadicarboxylic acid
1,10-bis(carboxymethylthiodecane)
1,10-bis(carboxymethylthio)decane
acetic acid, 2,2'-(1,10-decanediylbis(thio))bis-
SCHEMBL5597990
DTXSID80186497
1,10-bis(carboxy-methylthio)decane

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" In a separate dose-response study BCMTD was found to be a more potent inducer of peroxisomal beta-oxidation compared to tiadenol."( The hypolipidemic peroxisome-proliferating drug, bis(carboxymethylthio)-1.10 decane, a dicarboxylic metabolite of tiadenol, is activated to an acylcoenzyme A thioester.
Aarsaether, N; Aarsland, A; Berge, RK; Bremer, J, 1990)		0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (19)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (10.53)18.7374
1990's17 (89.47)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.31

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.31 (24.57)
Research Supply Index3.00 (2.92)
Research Growth Index5.30 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.31)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other19 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
acetic acid
Acetic Acid: Product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed). acetic acid : A simple monocarboxylic acid containing two carbons.		1.9910monocarboxylic acidantimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent
glycerol
Moon: The natural satellite of the planet Earth. It includes the lunar cycles or phases, the lunar month, lunar landscapes, geography, and soil.		1.9810alditol;
triol		algal metabolite;
detergent;
Escherichia coli metabolite;
geroprotector;
human metabolite;
mouse metabolite;
osmolyte;
Saccharomyces cerevisiae metabolite;
solvent
palmitic acid
Palmitic Acid: A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids.. hexadecanoic acid : A straight-chain, sixteen-carbon, saturated long-chain fatty acid.		3.0950long-chain fatty acid;
straight-chain saturated fatty acid		algal metabolite;
Daphnia magna metabolite;
EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor;
plant metabolite
cyanides
Cyanides: Inorganic salts of HYDROGEN CYANIDE containing the -CN radical. The concept also includes isocyanides. It is distinguished from NITRILES, which denotes organic compounds containing the -CN radical.. cyanides : Salts and C-organyl derivatives of hydrogen cyanide, HC#N.. isocyanide : The isomer HN(+)#C(-) of hydrocyanic acid, HC#N, and its hydrocarbyl derivatives RNC (RN(+)#C(-)).. cyanide : A pseudohalide anion that is the conjugate base of hydrogen cyanide.		1.9710pseudohalide anionEC 1.9.3.1 (cytochrome c oxidase) inhibitor
puromycin aminonucleoside
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine: structure in first source. 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine : Puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring.		1.98103'-deoxyribonucleoside;
adenosines
cytidine triphosphate
Cytidine Triphosphate: Cytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.		1.9810cytidine 5'-phosphate;
pyrimidine ribonucleoside 5'-triphosphate		Escherichia coli metabolite;
mouse metabolite
hexadecanedioic acid
hexadecanedioic acid : An alpha,omega-dicarboxylic acid that is the 1,14-dicarboxy derivative of tetradecane.		1.9710alpha,omega-dicarboxylic acid;
dicarboxylic fatty acid		human metabolite
tiadenol
tiadenol: structure		1.9710aliphatic sulfide
phenyl acetate
phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid.		2.3920benzenes;
phenyl acetates
methacycline
[no description available]		1.98101,2-diglyceride
coenzyme a
[no description available]		2.3820adenosine 3',5'-bisphosphatecoenzyme;
Escherichia coli metabolite;
mouse metabolite
propionyl-coenzyme a
propionyl-coenzyme A: RN given refers to parent cpd		1.9810acyl-CoAEscherichia coli metabolite;
metabolite;
mouse metabolite
1-(carboxymethylthio)tetradecane
1-(carboxymethylthio)tetradecane: structure given in first source; alkylthio acetic acid, non-beta-oxidizable		3.93130straight-chain fatty acid
1-(carboxyethylthio)tetradecane
1-(carboxyethylthio)tetradecane: structure given in first source; alkylthio propionic acid, non-beta-oxidizable		3.3670
acetyl coenzyme a
Acetyl Coenzyme A: Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.		1.9810acyl-CoAacyl donor;
coenzyme;
effector;
fundamental metabolite
3-hydroxy-3-methylglutaryl-coenzyme a
3-hydroxy-3-methylglutaryl-coenzyme A: RN given refers to cpd without isomeric designation. 3-hydroxy-3-methylglutaryl-CoA : An alpha,omega dicarboxyacyl-CoA that results from the formal condensation of the thiol group of coenzyme A with one of the carboxy groups of 3-hydroxy-3-methylglutaric acid.. (3S)-3-hydroxy-3-methylglutaryl-CoA : A 3-hydroxy-3-methylglutaryl-CoA where the 3-hydroxy-3-methylglutaryl component has (S)-configuration.		2103-hydroxy-3-methylglutaryl-CoA;
3-hydroxy fatty acyl-CoA		human metabolite;
mouse metabolite
oleic acid
Oleic Acid: An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed). oleic acid : An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.		1.9810octadec-9-enoic acidantioxidant;
Daphnia galeata metabolite;
EC 3.1.1.1 (carboxylesterase) inhibitor;
Escherichia coli metabolite;
mouse metabolite;
plant metabolite;
solvent
eicosapentaenoic acid
icosapentaenoic acid : Any straight-chain, C20 polyunsaturated fatty acid having five C=C double bonds.. all-cis-5,8,11,14,17-icosapentaenoic acid : An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17.		1.9910icosapentaenoic acid;
omega-3 fatty acid		anticholesteremic drug;
antidepressant;
antineoplastic agent;
Daphnia galeata metabolite;
fungal metabolite;
micronutrient;
mouse metabolite;
nutraceutical
sulfur
Sulfur: An element that is a member of the chalcogen family. It has an atomic symbol S, atomic number 16, and atomic weight [32.059; 32.076]. It is found in the amino acids cysteine and methionine.		1.9710chalcogen;
nonmetal atom		macronutrient
nad
NAD(1-) : An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety.		1.9810organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
phosphatidylcholines
Phosphatidylcholines: Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety.		1.98101,2-diacyl-sn-glycero-3-phosphocholine
ConditionIndicatedRelationship StrengthStudiesTrials
Nephrosis
Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.		01.9810