1,1,6-trimethyl-1,2-dihydronaphthalene

Description

1,1,6-trimethyl-1,2-dihydronaphthalene, often abbreviated as **1,1,6-TM-DHN**, is a **hydrocarbon compound** belonging to the **dihydronaphthalene family**.

Here's why it's important for research:

**1. Role in Cancer Research:**

* **Anticancer Activity:** 1,1,6-TM-DHN has demonstrated **anticancer activity** in preclinical studies against various types of cancer cells, including leukemia, lymphoma, breast cancer, and melanoma. This activity is attributed to its ability to induce apoptosis (programmed cell death) in cancer cells.
* **Target for Drug Development:** Due to its promising anticancer potential, 1,1,6-TM-DHN has become a target for the development of new anticancer drugs. Researchers are exploring ways to modify its structure to improve its potency, selectivity, and bioavailability.

**2. Chemical Biology Research:**

* **Synthesis and Reactivity:** The unique structure of 1,1,6-TM-DHN makes it a valuable tool for **organic synthesis and chemical biology research**. Its reactivity allows for the development of new synthetic methodologies and the investigation of chemical reaction mechanisms.
* **Fluorescence Properties:** Some derivatives of 1,1,6-TM-DHN exhibit fluorescence properties, which makes them useful for applications like **fluorescence microscopy** and **bioimaging**.

**3. Polymer Science:**

* **Polymers and Materials:** 1,1,6-TM-DHN can be incorporated into polymers and materials, providing them with specific properties such as enhanced thermal stability, increased conductivity, or modified optical properties.

**Overall, 1,1,6-TM-DHN is a versatile molecule with significant potential in various research areas. Its unique chemical structure and biological activity make it a valuable tool for understanding fundamental scientific principles and developing new technologies.**

**It is important to note that much research on 1,1,6-TM-DHN is still ongoing, and its full potential is yet to be fully explored.**

1,1,6-trimethyl-1,2-dihydronaphthalene: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]