Compounds > 1,1,2-trichloro-3,3,3-trifluoro-1-propene
Page last updated: 2024-11-06

1,1,2-trichloro-3,3,3-trifluoro-1-propene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1,1,2-trichloro-3,3,3-trifluoro-1-propene: nephrotoxic cpd; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID67938
SCHEMBL ID242971
MeSH IDM0167533

Synonyms (32)

Synonym
nsc-6824
1,2-trichloro-3,3,3-trifluoropropene
propene,1,2-trichloro-3,3,3-trifluoro-
1-propene,1,2-trichloro-3,3,3-trifluoro-
1,1-trifluoro-2,3,3-trichloropropene
nsc6824
431-52-7
1,2-trichlorotrifluoro-1-propene
propene, 1,1,2-trichloro-3,3,3-trifluoro-
1-propene, 1,1,2-trichloro-3,3,3-trifluoro-
1,1,2-trichloro-3,3,3-trifluoro-1-propene
einecs 207-075-0
1,1,2-trichloro-3,3,3-trifluoropropene
7-methylhexahydro-2h-benzo[b][1,4]dioxepin-3(4h)-one
1,1,2-trichloro-3,3,3-trifluoroprop-1-ene
h2mq7f3kmq ,
unii-h2mq7f3kmq
nsc 6824
2,3,3-trichloro-1,1,1-trifluoro-2-propene
trifluorotrichloropropene
AKOS006229782
FT-0605982
SCHEMBL242971
1,1,2-trichlorotrifluoro-1-propene
1,1,1-trifluoro-2,3,3-trichloro-2-propene
1,1,2-trichloro-3,3,3-trifluoropropene-1
1,1,2-trichloro-3,3,3-trifluoro-1-propene #
1,1,1-trifluoro-2,3,3-trichloropropene
DTXSID8073184
mfcd00013672
cfc 1213xa
1,1,2-trichlorotrifluoroprop-1-ene

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" A combination of high resolution proton nuclear magnetic resonance (1H NMR) spectroscopy of urine, renal histopathology and more routinely used clinical chemistry methods has been used to explore the acute toxic and biochemical effects of S-(1,2-dichlorovinyl)-L-cysteine (DCVC), S-(1,2-dichlorovinyl)-L-homocysteine (DCVHC) and 1,1,2-trichloro-3,3,3-trifluoro-1-propene (TCTFP) up to 48 h following their administration to male Fischer 344 (F344) rats."( Studies on the comparative toxicity of S-(1,2-dichlorovinyl)-L-cysteine, S-(1,2-dichlorovinyl)-L-homocysteine and 1,1,2-trichloro-3,3,3-trifluoro-1-propene in the Fischer 344 rat.
Anthony, ML; Beddell, CR; Lindon, JC; Nicholson, JK, 1994)		0.67
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (3)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.56

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.56 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.36 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.56)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
trichloroethylene
Trichloroethylene: A highly volatile inhalation anesthetic used mainly in short surgical procedures where light anesthesia with good analgesia is required. It is also used as an industrial solvent. Prolonged exposure to high concentrations of the vapor can lead to cardiotoxicity and neurological impairment.. triol : A chemical compound containing three hydroxy groups.		2.0110chloroethenesinhalation anaesthetic;
mouse metabolite
tetrachloroethylene
Tetrachloroethylene: A chlorinated hydrocarbon used as an industrial solvent and cooling liquid in electrical transformers. It is a potential carcinogen.		2.0110chlorocarbon;
chloroethenes		nephrotoxic agent
trichlorofluoroethene
[no description available]		7.0110
homocysteine
Homocysteine: A thiol-containing amino acid formed by a demethylation of METHIONINE.. homocysteine : A sulfur-containing amino acid consisting of a glycine core with a 2-mercaptoethyl side-chain.. L-homocysteine : A homocysteine that has L configuration.		6.9810amino acid zwitterion;
homocysteine;
serine family amino acid		fundamental metabolite;
mouse metabolite
cysteine
Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3.		2.420cysteiniumfundamental metabolite
s-(1,2-dichlorovinyl)homocysteine
S-(1,2-dichlorovinyl)homocysteine: RN given refers to (E)-isomer		1.9810
ConditionIndicatedRelationship StrengthStudiesTrials
Necrosis
The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.		01.9810
Kidney Diseases
Pathological processes of the KIDNEY or its component tissues.		01.9710