Page last updated: 2024-12-06

1'-hydroxyestragole

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1'-hydroxyestragole is a natural compound found in plants, particularly in basil and tarragon. It is a derivative of estragole, an allylbenzene compound. 1'-hydroxyestragole has been studied for its potential biological effects, including its antioxidant and anti-inflammatory properties. Its synthesis can be achieved through various methods, including enzymatic oxidation of estragole. Studies have indicated that 1'-hydroxyestragole may have potential therapeutic applications in conditions such as cancer and neurodegenerative diseases. However, further research is required to fully understand its biological role and potential benefits.'

1'-hydroxyestragole: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID40003
CHEMBL ID181994
SCHEMBL ID1689680
MeSH IDM0062275

Synonyms (24)

Synonym
1-[4-(methyloxy)phenyl]prop-2-en-1-ol
1'-hydroxyestragole
51410-44-7
brn 1939006
1-hydroxyestragole
estragole, 1'-hydroxy-
alpha-ethenyl-4-methoxybenzenemethanol
ccris 1873
benzyl alcohol, p-methoxy-alpha-vinyl-
1-(4-methoxyphenyl)prop-2-en-1-ol
CHEMBL181994
AKOS006279321
3-06-00-05032 (beilstein handbook reference)
vinyl-4-methoxy phenylcarbinol
4-methoxy-alpha-vinylbenzyl alcohol
RUPMSBPCFQDMAY-UHFFFAOYSA-N
1-(4-methoxy-phenyl)-prop-2-en-1-ol
SCHEMBL1689680
DTXSID6020723
vinyl-p-methoxyphenylcarbinol
Q63088225
A902492
BCA41044
EN300-208408

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID248765Inhibitory concentration of compound on nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages2005Bioorganic & medicinal chemistry letters, Apr-01, Volume: 15, Issue:7
Structure-activity relationships of 1'S-1'-acetoxychavicol acetate for inhibitory effect on NO production in lipopolysaccharide-activated mouse peritoneal macrophages.
AID253441Concentration with cytotoxic effect on mouse peritoneal macrophages2005Bioorganic & medicinal chemistry letters, Apr-01, Volume: 15, Issue:7
Structure-activity relationships of 1'S-1'-acetoxychavicol acetate for inhibitory effect on NO production in lipopolysaccharide-activated mouse peritoneal macrophages.
AID252044Percent inhibition of nitric oxide (NO) production in lipopolysaccharide activated mouse peritoneal macrophages at 100 uM of compound2005Bioorganic & medicinal chemistry letters, Apr-01, Volume: 15, Issue:7
Structure-activity relationships of 1'S-1'-acetoxychavicol acetate for inhibitory effect on NO production in lipopolysaccharide-activated mouse peritoneal macrophages.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (22)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (27.27)18.7374
1990's0 (0.00)18.2507
2000's8 (36.36)29.6817
2010's6 (27.27)24.3611
2020's2 (9.09)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.11

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.11 (24.57)
Research Supply Index3.14 (2.92)
Research Growth Index4.25 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.11)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other22 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]