Page last updated: 2024-12-07
1-(n-dimethyl)amino-7-naphthol
You are likely referring to **1-(N,N-dimethylamino)-7-naphthol**, also known as **7-hydroxy-1-dimethylaminonaphthalene**.
**Structure and Properties:**
* It's a bright yellow solid with a melting point of 123–124 °C.
* It contains a naphthalene ring with a hydroxyl group at position 7 and a dimethylamino group at position 1.
* This molecule is both fluorescent and chemiluminescent, meaning it can emit light when excited by radiation (fluorescence) or a chemical reaction (chemiluminescence).
**Importance in Research:**
1. **Fluorescence Studies:** 1-(N,N-dimethylamino)-7-naphthol is widely used as a fluorescent probe in various research fields, including:
* **Analytical Chemistry:** Detecting trace amounts of analytes, such as metal ions, in samples.
* **Biochemistry and Cell Biology:** Studying the dynamics of biological systems and processes, for instance, protein folding and membrane permeability.
* **Materials Science:** Investigating the properties of new materials.
2. **Chemiluminescence Applications:**
* **Analytical Chemistry:** It can be used as a reagent in chemiluminescent assays for sensitive detection of analytes, often coupled with flow injection analysis.
* **Forensic Science:** It can be used in forensic investigations as a luminol analog.
3. **Organic Synthesis:**
* 1-(N,N-dimethylamino)-7-naphthol serves as a starting material for the synthesis of various organic compounds, particularly dyes and pharmaceuticals.
**Key Advantages:**
* **High Quantum Yield:** Its fluorescence properties make it highly efficient in converting light energy into emitted light.
* **Good Photostability:** It exhibits relatively good stability under UV irradiation, making it suitable for long-term fluorescence measurements.
* **Sensitivity:** It's highly sensitive to its environment, making it valuable for detecting subtle changes in concentration or pH.
**Overall, 1-(N,N-dimethylamino)-7-naphthol is a versatile compound with a wide range of applications in diverse scientific fields due to its unique fluorescence and chemiluminescence properties, as well as its usefulness as a reagent in synthetic chemistry.**
Cross-References
Synonyms (8)
Synonym |
dman |
8-(dimethylamino)naphthalen-2-ol |
55346-51-5 |
2-naphthalenol, 8-(dimethylamino)- |
1-(n-dimethyl)amino-7-naphthol |
CHEMBL3126337 , |
bdbm50449365 |
DTXSID80970691 |
Protein Targets (1)
Inhibition Measurements
Biological Processes (16)
Molecular Functions (6)
Ceullar Components (8)
Research
Studies (4)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 1 (25.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 2 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.64
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 12.64 (24.57) | Research Supply Index | 1.95 (2.92) | Research Growth Index | 4.59 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 6 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |