1-(indol-4-yloxy)-3-(1-(4-azido-3-iodophenyl)-2-isobutylamine)-2-propanol

Description

The compound you described, **1-(indol-4-yloxy)-3-(1-(4-azido-3-iodophenyl)-2-isobutylamine)-2-propanol**, is a complex organic molecule with a specific structure designed for a particular research purpose.

Here's a breakdown of its components and its significance in research:

* **Indol-4-yloxy:** This is a derivative of indole, a heterocyclic compound found in the amino acid tryptophan. It might be incorporated into the molecule for its potential biological activity.
* **1-(4-azido-3-iodophenyl)-2-isobutylamine:** This part is crucial for the compound's function. The presence of an **azido group (N3)** makes it a **photoreactive molecule**. This means it can be activated by light, leading to the formation of a highly reactive **nitrene**.
* **2-propanol:** This is a simple alcohol group that might be used to increase the molecule's solubility in biological systems.

**Significance in Research:**

This compound likely functions as a **photoaffinity label**. Photoaffinity labels are used in research to study **protein-protein interactions** and **protein-ligand binding**.

**How it works:**

1. The compound binds to its target protein.
2. Upon exposure to light, the azido group is activated, forming a nitrene.
3. The highly reactive nitrene covalently binds to the target protein, essentially labeling it.
4. By analyzing the labeled protein, researchers can identify the binding site of the compound and gain insights into the protein's function.

**Potential Applications:**

* **Drug discovery:** Identifying potential binding sites on proteins could lead to the development of new drugs.
* **Understanding biological pathways:** Studying protein-protein interactions can shed light on complex cellular processes.
* **Diagnostics:** Labeling specific proteins could be used for diagnostic imaging or detecting disease markers.

**It's important to note that the compound itself is a hypothetical example, and its specific applications would depend on the precise research question being addressed.**

If you have more information about the specific research context or application, I can provide more detailed insights.

1-(indol-4-yloxy)-3-(1-(4-azido-3-iodophenyl)-2-isobutylamine)-2-propanol: RN given refers to (+-)-isomer; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]