Page last updated: 2024-12-07

1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

You're asking about a compound called **1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene**, also known by its IUPAC name, **(E)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene**. This compound is a type of **stilbene**, a class of organic compounds with a specific structural feature: a central ethylene (C=C) bond connecting two aromatic rings.

Here's a breakdown:

* **Structure:** The molecule has a double bond (C=C) at its center, with a 4-methoxyphenyl ring (a benzene ring with a methoxy group attached at the 4th position) attached to one end and a 3,4,5-trimethoxyphenyl ring (a benzene ring with three methoxy groups at positions 3, 4, and 5) attached to the other end.
* **Properties:** It's likely a solid at room temperature, and its exact properties would depend on factors like its purity and crystalline form.
* **Importance in research:** Stilbenes, including this specific compound, are interesting for several research areas:

* **Pharmacology:** Some stilbenes have shown biological activity as:
* **Antioxidants:** They can help protect cells from damage caused by free radicals.
* **Anti-inflammatory agents:** They can reduce inflammation in the body.
* **Anti-cancer agents:** Some have been studied for their potential to inhibit cancer cell growth.
* **Antimicrobial agents:** They might have activity against certain bacteria and fungi.
* **Materials Science:** Stilbenes can be used in the synthesis of polymers and other materials with unique properties.
* **Organic Chemistry:** They serve as model compounds for understanding the reactivity and photochemistry of organic molecules.

**Note:** It's important to remember that the specific importance of this exact compound (1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene) might be limited. Research on stilbenes focuses on the entire class of compounds, with various substituents and modifications, to explore their diverse biological and chemical properties.

If you have a specific research area in mind, it might be helpful to provide more context to understand the relevance of this particular stilbene derivative.

1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene, also known as **resveratrol**, is a naturally occurring stilbene compound found in various plants, including grapes, peanuts, and berries.

**Importance in Research:**

Resveratrol has attracted significant research interest due to its diverse biological activities and potential health benefits. Here are some key areas where it plays a role:

* **Antioxidant Activity:** Resveratrol acts as a potent antioxidant, neutralizing free radicals that damage cells and contribute to aging and disease.
* **Cardiovascular Health:** Studies suggest resveratrol may improve heart health by reducing blood pressure, lowering cholesterol levels, and protecting blood vessels from damage.
* **Cancer Prevention:** Resveratrol has shown promise in inhibiting the growth and spread of cancer cells in laboratory studies, particularly for cancers like breast, colon, and prostate cancer.
* **Neuroprotective Effects:** Research indicates that resveratrol may protect brain cells from damage caused by oxidative stress, inflammation, and aging, potentially mitigating cognitive decline and neurodegenerative diseases like Alzheimer's and Parkinson's.
* **Anti-inflammatory Properties:** Resveratrol possesses anti-inflammatory properties that may help reduce inflammation in various tissues and organs.
* **Metabolic Regulation:** Resveratrol has been linked to improvements in insulin sensitivity and glucose metabolism, potentially aiding in the management of diabetes.
* **Lifespan Extension:** Studies in animal models have shown that resveratrol can extend lifespan and improve healthspan.

**Current Research Focus:**

Current research on resveratrol focuses on:

* Understanding its mechanisms of action at the molecular level.
* Developing safe and effective ways to deliver resveratrol to the body.
* Evaluating its long-term effects in humans.
* Exploring its potential therapeutic applications in various diseases.

**Conclusion:**

Resveratrol is a natural compound with a wide range of biological activities, making it a promising candidate for various health benefits and therapeutic applications. Ongoing research is exploring its potential to prevent and treat chronic diseases, promote healthy aging, and enhance overall well-being.

1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene: inhibits tubulin polymerization; RN & structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID125922
MeSH IDM0191925
PubMed CID5388779
CHEMBL ID47426
SCHEMBL ID3834841
MeSH IDM0191925

Synonyms (28)

Synonym
NCI60_010242
NCI60_012884
3,4,5,4'-tetramethoxystilbene
1,2,3-trimethoxy-5-[2-(4-methoxyphenyl)ethenyl]benzene
1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene
3,4,4',5-tetramethoxystilbene
GGFQQRXTLIJXNY-UHFFFAOYSA-N
FT-0770743
BCP31049
DTXSID201341726
(z) 3,4',5-tetramethoxystilbene
nsc638499
nsc-638499
CHEMBL47426 ,
10z-3,4,4',5-tetramethoxystilbene
1,2,3-trimethoxy-5-[(z)-2-(4-methoxyphenyl)ethenyl]benzene
1,2,3-trimethoxy-5-[(z)-2-(4-methoxy-phenyl)-vinyl]-benzene
5-(4-methoxystyryl)-1,2,3-trimethoxybenzene
bdbm50006677
10z-3,4,4'',5-tetramethoxystilbene
1,2,3-trimethoxy-5-[2-(4-methoxy-phenyl)-vinyl]-benzene
3,4,4'',5-tetramethoxy-(z)-stilbene
(z)-1,2,3-trimethoxy-5-(2-(4-methoxyphenyl)ethenyl)benzene
1-mtpe
benzene, 1,2,3-trimethoxy-5-(2-(4-methoxyphenyl)ethenyl)-, (z)-
SCHEMBL3834841
cis-3,4,5,4'-tetramethoxystilbene
PD181080

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" As part of a chemoprevention drug development programme, the pharmacokinetic properties of DMU 212 were compared with those of resveratrol in the plasma, liver, kidney, lung, heart, brain and small intestinal and colonic mucosa of mice."( Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4'-tetramethoxystilbene.
Boocock, D; Farmer, PB; Gescher, AJ; Jones, DJ; Potter, GA; Ruparelia, KC; Sale, S; Steward, WP; Verschoyle, RD; Wilsher, N, 2004
)
0.32
" The pharmacokinetic profiles of MR-4 were subsequently assessed in rats using 2-hydroxypropyl-β-cyclodextrin as a dosing vehicle."( Quantification of trans-3,4,5,4'-Tetramethoxystilbene in rat plasma by HPLC: application to pharmacokinetic study.
Go, ML; Ho, PC; Lin, HS; Spatafora, C; Tringali, C; Zhang, W, 2011
)
0.37

Bioavailability

ExcerptReferenceRelevance
" However, the absolute oral bioavailability of MR-4 was low (6."( Quantification of trans-3,4,5,4'-Tetramethoxystilbene in rat plasma by HPLC: application to pharmacokinetic study.
Go, ML; Ho, PC; Lin, HS; Spatafora, C; Tringali, C; Zhang, W, 2011
)
0.37
" The methylated analogues of resveratrol have been found to have higher bioavailability and cytotoxic activity than that of the prototupe compound."( The Effect of 4'-hydroxy-3,4,5-trimetoxystilbene, the Metabolite of Resveratrol Analogue DMU-212, on Growth, Cell Cycle and Apoptosis in DLD-1 and LOVO Colon Cancer Cell Lines.
Borys-Wojcik, S; Jodynis-Liebert, J; Jozkowiak, M; Kaczmarek, M; Nowicki, A; Piotrowska-Kempisty, H; Ramlau, P; Skupin-Mrugalska, P; Wierzchowski, M, 2020
)
0.56
" These results serve to highlight the contrasting effects on different activities brought about by methoxylation, which is widely employed as a structural modification approach to improve potency and bioavailability of resveratrol."( Methoxylation of resveratrol: effects on induction of NAD(P)H quinone-oxidoreductase 1 (NQO1) activity and growth inhibitory properties.
Go, ML; Zhang, W, 2011
)
0.37

Dosage Studied

ExcerptRelevanceReference
" The pharmacokinetic profiles of MR-4 were subsequently assessed in rats using 2-hydroxypropyl-β-cyclodextrin as a dosing vehicle."( Quantification of trans-3,4,5,4'-Tetramethoxystilbene in rat plasma by HPLC: application to pharmacokinetic study.
Go, ML; Ho, PC; Lin, HS; Spatafora, C; Tringali, C; Zhang, W, 2011
)
0.37
" All compounds activated AhR, but their efficacies, potencies and dose-response profiles differed substantially."( Hydroxystilbenes and methoxystilbenes activate human aryl hydrocarbon receptor and induce CYP1A genes in human hepatoma cells and human hepatocytes.
Bachleda, P; Dvořák, Z; Pastorková, B; Vrzalová, A, 2017
)
0.46
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (20)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Tubulin alpha-1A chainSus scrofa (pig)IC50 (µMol)1.30000.00672.160310.0000AID214546
Tubulin beta-4A chainHomo sapiens (human)IC50 (µMol)1.85000.00051.968010.0000AID273359; AID310083
Tubulin beta chainHomo sapiens (human)IC50 (µMol)1.85000.00052.052910.0000AID273359; AID310083
Tubulin alpha-3C chainHomo sapiens (human)IC50 (µMol)1.85000.00051.955510.0000AID273359; AID310083
TyrosinaseMus musculus (house mouse)IC50 (µMol)500.00000.03002.21045.2300AID1801525
Tubulin alpha-1B chainHomo sapiens (human)IC50 (µMol)1.85000.00051.955510.0000AID273359; AID310083
Tubulin alpha-4A chainHomo sapiens (human)IC50 (µMol)1.85000.00051.955510.0000AID273359; AID310083
Tubulin beta-4B chainHomo sapiens (human)IC50 (µMol)1.85000.00051.968010.0000AID273359; AID310083
Tubulin beta-3 chainHomo sapiens (human)IC50 (µMol)1.85000.00051.894510.0000AID273359; AID310083
Tubulin beta-2A chainHomo sapiens (human)IC50 (µMol)1.85000.00051.968010.0000AID273359; AID310083
Tubulin beta-8 chainHomo sapiens (human)IC50 (µMol)1.85000.00051.968010.0000AID273359; AID310083
Tubulin beta-2B chainBos taurus (cattle)IC50 (µMol)1.65000.25001.88388.7000AID214032; AID214160
Tubulin alpha-3E chainHomo sapiens (human)IC50 (µMol)1.85000.00051.955510.0000AID273359; AID310083
Tubulin alpha-1A chainHomo sapiens (human)IC50 (µMol)1.85000.00051.955510.0000AID273359; AID310083
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)IC50 (µMol)1.65000.25001.87798.7000AID214032; AID214160
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)IC50 (µMol)1.30000.25001.86568.7000AID214160
Tubulin alpha-1C chainHomo sapiens (human)IC50 (µMol)1.85000.00051.955510.0000AID273359; AID310083
Tubulin beta-6 chainHomo sapiens (human)IC50 (µMol)1.85000.00051.968010.0000AID273359; AID310083
Tubulin beta-2B chainHomo sapiens (human)IC50 (µMol)1.85000.00051.968010.0000AID273359; AID310083
Tubulin beta-1 chainHomo sapiens (human)IC50 (µMol)1.30000.00051.987010.0000AID241105; AID273359; AID310083
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (52)

Processvia Protein(s)Taxonomy
negative regulation of microtubule polymerizationTubulin beta-4A chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin beta-4A chainHomo sapiens (human)
mitotic cell cycleTubulin beta-4A chainHomo sapiens (human)
odontoblast differentiationTubulin beta chainHomo sapiens (human)
microtubule-based processTubulin beta chainHomo sapiens (human)
cytoskeleton-dependent intracellular transportTubulin beta chainHomo sapiens (human)
natural killer cell mediated cytotoxicityTubulin beta chainHomo sapiens (human)
regulation of synapse organizationTubulin beta chainHomo sapiens (human)
spindle assemblyTubulin beta chainHomo sapiens (human)
cell divisionTubulin beta chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin beta chainHomo sapiens (human)
mitotic cell cycleTubulin beta chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin alpha-3C chainHomo sapiens (human)
mitotic cell cycleTubulin alpha-3C chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin alpha-1B chainHomo sapiens (human)
microtubule-based processTubulin alpha-1B chainHomo sapiens (human)
cytoskeleton-dependent intracellular transportTubulin alpha-1B chainHomo sapiens (human)
cell divisionTubulin alpha-1B chainHomo sapiens (human)
cellular response to interleukin-4Tubulin alpha-1B chainHomo sapiens (human)
mitotic cell cycleTubulin alpha-1B chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin alpha-4A chainHomo sapiens (human)
mitotic cell cycleTubulin alpha-4A chainHomo sapiens (human)
natural killer cell mediated cytotoxicityTubulin beta-4B chainHomo sapiens (human)
mitotic cell cycleTubulin beta-4B chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin beta-4B chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin beta-3 chainHomo sapiens (human)
axon guidanceTubulin beta-3 chainHomo sapiens (human)
netrin-activated signaling pathwayTubulin beta-3 chainHomo sapiens (human)
dorsal root ganglion developmentTubulin beta-3 chainHomo sapiens (human)
mitotic cell cycleTubulin beta-3 chainHomo sapiens (human)
cerebral cortex developmentTubulin beta-2A chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin beta-2A chainHomo sapiens (human)
mitotic cell cycleTubulin beta-2A chainHomo sapiens (human)
oocyte maturationTubulin beta-8 chainHomo sapiens (human)
spindle assembly involved in female meiosisTubulin beta-8 chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin beta-8 chainHomo sapiens (human)
mitotic cell cycleTubulin beta-8 chainHomo sapiens (human)
microtubule-based processTubulin beta-2B chainBos taurus (cattle)
nervous system developmentTubulin beta-2B chainBos taurus (cattle)
positive regulation of axon guidanceTubulin beta-2B chainBos taurus (cattle)
biological_processTubulin alpha-3E chainHomo sapiens (human)
mitotic cell cycleTubulin alpha-3E chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin alpha-3E chainHomo sapiens (human)
neuron migrationTubulin alpha-1A chainHomo sapiens (human)
startle responseTubulin alpha-1A chainHomo sapiens (human)
intracellular protein transportTubulin alpha-1A chainHomo sapiens (human)
microtubule-based processTubulin alpha-1A chainHomo sapiens (human)
centrosome cycleTubulin alpha-1A chainHomo sapiens (human)
smoothened signaling pathwayTubulin alpha-1A chainHomo sapiens (human)
memoryTubulin alpha-1A chainHomo sapiens (human)
adult locomotory behaviorTubulin alpha-1A chainHomo sapiens (human)
visual learningTubulin alpha-1A chainHomo sapiens (human)
response to mechanical stimulusTubulin alpha-1A chainHomo sapiens (human)
glial cell differentiationTubulin alpha-1A chainHomo sapiens (human)
gene expressionTubulin alpha-1A chainHomo sapiens (human)
dentate gyrus developmentTubulin alpha-1A chainHomo sapiens (human)
cerebellar cortex morphogenesisTubulin alpha-1A chainHomo sapiens (human)
pyramidal neuron differentiationTubulin alpha-1A chainHomo sapiens (human)
cerebral cortex developmentTubulin alpha-1A chainHomo sapiens (human)
cytoskeleton-dependent intracellular transportTubulin alpha-1A chainHomo sapiens (human)
response to tumor necrosis factorTubulin alpha-1A chainHomo sapiens (human)
locomotory exploration behaviorTubulin alpha-1A chainHomo sapiens (human)
microtubule polymerizationTubulin alpha-1A chainHomo sapiens (human)
forebrain morphogenesisTubulin alpha-1A chainHomo sapiens (human)
homeostasis of number of cells within a tissueTubulin alpha-1A chainHomo sapiens (human)
regulation of synapse organizationTubulin alpha-1A chainHomo sapiens (human)
synapse organizationTubulin alpha-1A chainHomo sapiens (human)
cell divisionTubulin alpha-1A chainHomo sapiens (human)
neuron apoptotic processTubulin alpha-1A chainHomo sapiens (human)
motor behaviorTubulin alpha-1A chainHomo sapiens (human)
cellular response to calcium ionTubulin alpha-1A chainHomo sapiens (human)
organelle transport along microtubuleTubulin alpha-1A chainHomo sapiens (human)
neuron projection arborizationTubulin alpha-1A chainHomo sapiens (human)
response to L-glutamateTubulin alpha-1A chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin alpha-1A chainHomo sapiens (human)
mitotic cell cycleTubulin alpha-1A chainHomo sapiens (human)
microtubule-based processTubulin alpha-1C chainHomo sapiens (human)
cytoskeleton-dependent intracellular transportTubulin alpha-1C chainHomo sapiens (human)
cell divisionTubulin alpha-1C chainHomo sapiens (human)
mitotic cell cycleTubulin alpha-1C chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin alpha-1C chainHomo sapiens (human)
mitotic cell cycleTubulin beta-6 chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin beta-6 chainHomo sapiens (human)
neuron migrationTubulin beta-2B chainHomo sapiens (human)
microtubule-based processTubulin beta-2B chainHomo sapiens (human)
cerebral cortex developmentTubulin beta-2B chainHomo sapiens (human)
modulation of chemical synaptic transmissionTubulin beta-2B chainHomo sapiens (human)
positive regulation of axon guidanceTubulin beta-2B chainHomo sapiens (human)
embryonic brain developmentTubulin beta-2B chainHomo sapiens (human)
mitotic cell cycleTubulin beta-2B chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin beta-2B chainHomo sapiens (human)
platelet formationTubulin beta-1 chainHomo sapiens (human)
thyroid gland developmentTubulin beta-1 chainHomo sapiens (human)
microtubule polymerizationTubulin beta-1 chainHomo sapiens (human)
spindle assemblyTubulin beta-1 chainHomo sapiens (human)
thyroid hormone transportTubulin beta-1 chainHomo sapiens (human)
platelet aggregationTubulin beta-1 chainHomo sapiens (human)
mitotic cell cycleTubulin beta-1 chainHomo sapiens (human)
microtubule cytoskeleton organizationTubulin beta-1 chainHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (21)

Processvia Protein(s)Taxonomy
GTPase activityTubulin beta-4A chainHomo sapiens (human)
calcium ion bindingTubulin beta-4A chainHomo sapiens (human)
protein bindingTubulin beta-4A chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin beta-4A chainHomo sapiens (human)
GTP bindingTubulin beta-4A chainHomo sapiens (human)
GTPase activityTubulin beta chainHomo sapiens (human)
structural molecule activityTubulin beta chainHomo sapiens (human)
protein bindingTubulin beta chainHomo sapiens (human)
protein domain specific bindingTubulin beta chainHomo sapiens (human)
ubiquitin protein ligase bindingTubulin beta chainHomo sapiens (human)
GTPase activating protein bindingTubulin beta chainHomo sapiens (human)
MHC class I protein bindingTubulin beta chainHomo sapiens (human)
protein-containing complex bindingTubulin beta chainHomo sapiens (human)
metal ion bindingTubulin beta chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin beta chainHomo sapiens (human)
GTP bindingTubulin beta chainHomo sapiens (human)
hydrolase activityTubulin alpha-3C chainHomo sapiens (human)
metal ion bindingTubulin alpha-3C chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin alpha-3C chainHomo sapiens (human)
GTP bindingTubulin alpha-3C chainHomo sapiens (human)
double-stranded RNA bindingTubulin alpha-1B chainHomo sapiens (human)
GTPase activityTubulin alpha-1B chainHomo sapiens (human)
structural molecule activityTubulin alpha-1B chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin alpha-1B chainHomo sapiens (human)
protein bindingTubulin alpha-1B chainHomo sapiens (human)
GTP bindingTubulin alpha-1B chainHomo sapiens (human)
ubiquitin protein ligase bindingTubulin alpha-1B chainHomo sapiens (human)
protein bindingTubulin alpha-4A chainHomo sapiens (human)
hydrolase activityTubulin alpha-4A chainHomo sapiens (human)
protein kinase bindingTubulin alpha-4A chainHomo sapiens (human)
metal ion bindingTubulin alpha-4A chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin alpha-4A chainHomo sapiens (human)
GTP bindingTubulin alpha-4A chainHomo sapiens (human)
double-stranded RNA bindingTubulin beta-4B chainHomo sapiens (human)
GTPase activityTubulin beta-4B chainHomo sapiens (human)
protein bindingTubulin beta-4B chainHomo sapiens (human)
MHC class I protein bindingTubulin beta-4B chainHomo sapiens (human)
metal ion bindingTubulin beta-4B chainHomo sapiens (human)
unfolded protein bindingTubulin beta-4B chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin beta-4B chainHomo sapiens (human)
GTP bindingTubulin beta-4B chainHomo sapiens (human)
GTPase activityTubulin beta-3 chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin beta-3 chainHomo sapiens (human)
protein bindingTubulin beta-3 chainHomo sapiens (human)
GTP bindingTubulin beta-3 chainHomo sapiens (human)
peptide bindingTubulin beta-3 chainHomo sapiens (human)
metal ion bindingTubulin beta-3 chainHomo sapiens (human)
netrin receptor bindingTubulin beta-3 chainHomo sapiens (human)
GTPase activityTubulin beta-2A chainHomo sapiens (human)
protein bindingTubulin beta-2A chainHomo sapiens (human)
metal ion bindingTubulin beta-2A chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin beta-2A chainHomo sapiens (human)
GTP bindingTubulin beta-2A chainHomo sapiens (human)
molecular_functionTubulin beta-8 chainHomo sapiens (human)
GTPase activityTubulin beta-8 chainHomo sapiens (human)
metal ion bindingTubulin beta-8 chainHomo sapiens (human)
GTP bindingTubulin beta-8 chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin beta-8 chainHomo sapiens (human)
GTPase activityTubulin beta-2B chainBos taurus (cattle)
metal ion bindingTubulin beta-2B chainBos taurus (cattle)
protein heterodimerization activityTubulin beta-2B chainBos taurus (cattle)
molecular_functionTubulin alpha-3E chainHomo sapiens (human)
protein bindingTubulin alpha-3E chainHomo sapiens (human)
hydrolase activityTubulin alpha-3E chainHomo sapiens (human)
metal ion bindingTubulin alpha-3E chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin alpha-3E chainHomo sapiens (human)
GTP bindingTubulin alpha-3E chainHomo sapiens (human)
structural molecule activityTubulin alpha-1A chainHomo sapiens (human)
protein bindingTubulin alpha-1A chainHomo sapiens (human)
hydrolase activityTubulin alpha-1A chainHomo sapiens (human)
identical protein bindingTubulin alpha-1A chainHomo sapiens (human)
protein-containing complex bindingTubulin alpha-1A chainHomo sapiens (human)
metal ion bindingTubulin alpha-1A chainHomo sapiens (human)
protein heterodimerization activityTubulin alpha-1A chainHomo sapiens (human)
GTP bindingTubulin alpha-1A chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin alpha-1A chainHomo sapiens (human)
structural molecule activityTubulin alpha-1C chainHomo sapiens (human)
protein bindingTubulin alpha-1C chainHomo sapiens (human)
hydrolase activityTubulin alpha-1C chainHomo sapiens (human)
metal ion bindingTubulin alpha-1C chainHomo sapiens (human)
GTP bindingTubulin alpha-1C chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin alpha-1C chainHomo sapiens (human)
molecular_functionTubulin beta-6 chainHomo sapiens (human)
GTPase activityTubulin beta-6 chainHomo sapiens (human)
protein bindingTubulin beta-6 chainHomo sapiens (human)
metal ion bindingTubulin beta-6 chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin beta-6 chainHomo sapiens (human)
GTP bindingTubulin beta-6 chainHomo sapiens (human)
GTPase activityTubulin beta-2B chainHomo sapiens (human)
protein bindingTubulin beta-2B chainHomo sapiens (human)
metal ion bindingTubulin beta-2B chainHomo sapiens (human)
protein heterodimerization activityTubulin beta-2B chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin beta-2B chainHomo sapiens (human)
GTP bindingTubulin beta-2B chainHomo sapiens (human)
GTPase activityTubulin beta-1 chainHomo sapiens (human)
metal ion bindingTubulin beta-1 chainHomo sapiens (human)
structural constituent of cytoskeletonTubulin beta-1 chainHomo sapiens (human)
GTP bindingTubulin beta-1 chainHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (36)

Processvia Protein(s)Taxonomy
nucleusTubulin beta-4A chainHomo sapiens (human)
cytosolTubulin beta-4A chainHomo sapiens (human)
microtubuleTubulin beta-4A chainHomo sapiens (human)
axonemeTubulin beta-4A chainHomo sapiens (human)
microtubule cytoskeletonTubulin beta-4A chainHomo sapiens (human)
internode region of axonTubulin beta-4A chainHomo sapiens (human)
neuronal cell bodyTubulin beta-4A chainHomo sapiens (human)
myelin sheathTubulin beta-4A chainHomo sapiens (human)
intercellular bridgeTubulin beta-4A chainHomo sapiens (human)
extracellular exosomeTubulin beta-4A chainHomo sapiens (human)
mitotic spindleTubulin beta-4A chainHomo sapiens (human)
microtubuleTubulin beta-4A chainHomo sapiens (human)
cytoplasmTubulin beta-4A chainHomo sapiens (human)
extracellular regionTubulin beta chainHomo sapiens (human)
nucleusTubulin beta chainHomo sapiens (human)
nuclear envelope lumenTubulin beta chainHomo sapiens (human)
cytoplasmTubulin beta chainHomo sapiens (human)
cytosolTubulin beta chainHomo sapiens (human)
cytoskeletonTubulin beta chainHomo sapiens (human)
microtubuleTubulin beta chainHomo sapiens (human)
microtubule cytoskeletonTubulin beta chainHomo sapiens (human)
azurophil granule lumenTubulin beta chainHomo sapiens (human)
cytoplasmic ribonucleoprotein granuleTubulin beta chainHomo sapiens (human)
cell bodyTubulin beta chainHomo sapiens (human)
membrane raftTubulin beta chainHomo sapiens (human)
intercellular bridgeTubulin beta chainHomo sapiens (human)
extracellular exosomeTubulin beta chainHomo sapiens (human)
mitotic spindleTubulin beta chainHomo sapiens (human)
protein-containing complexTubulin beta chainHomo sapiens (human)
cytoplasmTubulin beta chainHomo sapiens (human)
microtubuleTubulin beta chainHomo sapiens (human)
nucleusTubulin alpha-3C chainHomo sapiens (human)
microtubule cytoskeletonTubulin alpha-3C chainHomo sapiens (human)
microtubuleTubulin alpha-3C chainHomo sapiens (human)
cytoplasmTubulin alpha-3C chainHomo sapiens (human)
microtubule cytoskeletonTubulin alpha-1B chainHomo sapiens (human)
microtubuleTubulin alpha-1B chainHomo sapiens (human)
cytoplasmic microtubuleTubulin alpha-1B chainHomo sapiens (human)
microtubule cytoskeletonTubulin alpha-1B chainHomo sapiens (human)
microtubuleTubulin alpha-1B chainHomo sapiens (human)
cytoplasmTubulin alpha-1B chainHomo sapiens (human)
extracellular regionTubulin alpha-4A chainHomo sapiens (human)
cytosolTubulin alpha-4A chainHomo sapiens (human)
cytoskeletonTubulin alpha-4A chainHomo sapiens (human)
microtubuleTubulin alpha-4A chainHomo sapiens (human)
microtubule cytoskeletonTubulin alpha-4A chainHomo sapiens (human)
extracellular exosomeTubulin alpha-4A chainHomo sapiens (human)
cytoplasmTubulin alpha-4A chainHomo sapiens (human)
microtubuleTubulin alpha-4A chainHomo sapiens (human)
extracellular regionTubulin beta-4B chainHomo sapiens (human)
nucleusTubulin beta-4B chainHomo sapiens (human)
cytosolTubulin beta-4B chainHomo sapiens (human)
cytoskeletonTubulin beta-4B chainHomo sapiens (human)
microtubuleTubulin beta-4B chainHomo sapiens (human)
axonemal microtubuleTubulin beta-4B chainHomo sapiens (human)
microtubule cytoskeletonTubulin beta-4B chainHomo sapiens (human)
azurophil granule lumenTubulin beta-4B chainHomo sapiens (human)
intercellular bridgeTubulin beta-4B chainHomo sapiens (human)
extracellular exosomeTubulin beta-4B chainHomo sapiens (human)
mitotic spindleTubulin beta-4B chainHomo sapiens (human)
extracellular vesicleTubulin beta-4B chainHomo sapiens (human)
microtubuleTubulin beta-4B chainHomo sapiens (human)
cytoplasmTubulin beta-4B chainHomo sapiens (human)
microtubule cytoskeletonTubulin beta-3 chainHomo sapiens (human)
nucleusTubulin beta-3 chainHomo sapiens (human)
microtubuleTubulin beta-3 chainHomo sapiens (human)
microtubule cytoskeletonTubulin beta-3 chainHomo sapiens (human)
lamellipodiumTubulin beta-3 chainHomo sapiens (human)
filopodiumTubulin beta-3 chainHomo sapiens (human)
axonTubulin beta-3 chainHomo sapiens (human)
dendriteTubulin beta-3 chainHomo sapiens (human)
growth coneTubulin beta-3 chainHomo sapiens (human)
neuronal cell bodyTubulin beta-3 chainHomo sapiens (human)
intercellular bridgeTubulin beta-3 chainHomo sapiens (human)
extracellular exosomeTubulin beta-3 chainHomo sapiens (human)
cell peripheryTubulin beta-3 chainHomo sapiens (human)
mitotic spindleTubulin beta-3 chainHomo sapiens (human)
microtubuleTubulin beta-3 chainHomo sapiens (human)
cytoplasmTubulin beta-3 chainHomo sapiens (human)
nucleusTubulin beta-2A chainHomo sapiens (human)
microtubuleTubulin beta-2A chainHomo sapiens (human)
microtubule cytoskeletonTubulin beta-2A chainHomo sapiens (human)
intercellular bridgeTubulin beta-2A chainHomo sapiens (human)
extracellular exosomeTubulin beta-2A chainHomo sapiens (human)
mitotic spindleTubulin beta-2A chainHomo sapiens (human)
extracellular vesicleTubulin beta-2A chainHomo sapiens (human)
cytoplasmTubulin beta-2A chainHomo sapiens (human)
microtubuleTubulin beta-2A chainHomo sapiens (human)
microtubule cytoskeletonTubulin beta-8 chainHomo sapiens (human)
intercellular bridgeTubulin beta-8 chainHomo sapiens (human)
extracellular exosomeTubulin beta-8 chainHomo sapiens (human)
mitotic spindleTubulin beta-8 chainHomo sapiens (human)
meiotic spindleTubulin beta-8 chainHomo sapiens (human)
microtubuleTubulin beta-8 chainHomo sapiens (human)
cytoplasmTubulin beta-8 chainHomo sapiens (human)
microtubule cytoskeletonTubulin beta-2B chainBos taurus (cattle)
nucleusTubulin alpha-3E chainHomo sapiens (human)
microtubule cytoskeletonTubulin alpha-3E chainHomo sapiens (human)
microtubuleTubulin alpha-3E chainHomo sapiens (human)
cytoplasmTubulin alpha-3E chainHomo sapiens (human)
condensed chromosomeTubulin alpha-1A chainHomo sapiens (human)
nucleusTubulin alpha-1A chainHomo sapiens (human)
cytosolTubulin alpha-1A chainHomo sapiens (human)
microtubuleTubulin alpha-1A chainHomo sapiens (human)
axonemal microtubuleTubulin alpha-1A chainHomo sapiens (human)
plasma membraneTubulin alpha-1A chainHomo sapiens (human)
microtubule cytoskeletonTubulin alpha-1A chainHomo sapiens (human)
neuromuscular junctionTubulin alpha-1A chainHomo sapiens (human)
cytoplasmic ribonucleoprotein granuleTubulin alpha-1A chainHomo sapiens (human)
recycling endosomeTubulin alpha-1A chainHomo sapiens (human)
extracellular exosomeTubulin alpha-1A chainHomo sapiens (human)
microtubuleTubulin alpha-1A chainHomo sapiens (human)
cytoplasmTubulin alpha-1A chainHomo sapiens (human)
nucleusTubulin alpha-1C chainHomo sapiens (human)
microtubuleTubulin alpha-1C chainHomo sapiens (human)
cytoplasmic microtubuleTubulin alpha-1C chainHomo sapiens (human)
microtubule cytoskeletonTubulin alpha-1C chainHomo sapiens (human)
vesicleTubulin alpha-1C chainHomo sapiens (human)
membrane raftTubulin alpha-1C chainHomo sapiens (human)
microtubuleTubulin alpha-1C chainHomo sapiens (human)
cytoplasmTubulin alpha-1C chainHomo sapiens (human)
nucleusTubulin beta-6 chainHomo sapiens (human)
microtubuleTubulin beta-6 chainHomo sapiens (human)
microtubule cytoskeletonTubulin beta-6 chainHomo sapiens (human)
intercellular bridgeTubulin beta-6 chainHomo sapiens (human)
extracellular exosomeTubulin beta-6 chainHomo sapiens (human)
mitotic spindleTubulin beta-6 chainHomo sapiens (human)
cytoplasmTubulin beta-6 chainHomo sapiens (human)
microtubuleTubulin beta-6 chainHomo sapiens (human)
nucleusTubulin beta-2B chainHomo sapiens (human)
microtubuleTubulin beta-2B chainHomo sapiens (human)
microtubule cytoskeletonTubulin beta-2B chainHomo sapiens (human)
intercellular bridgeTubulin beta-2B chainHomo sapiens (human)
mitotic spindleTubulin beta-2B chainHomo sapiens (human)
Schaffer collateral - CA1 synapseTubulin beta-2B chainHomo sapiens (human)
microtubuleTubulin beta-2B chainHomo sapiens (human)
cytoplasmTubulin beta-2B chainHomo sapiens (human)
cytoplasmTubulin beta-1 chainHomo sapiens (human)
microtubule cytoskeletonTubulin beta-1 chainHomo sapiens (human)
intercellular bridgeTubulin beta-1 chainHomo sapiens (human)
extracellular exosomeTubulin beta-1 chainHomo sapiens (human)
mitotic spindleTubulin beta-1 chainHomo sapiens (human)
microtubuleTubulin beta-1 chainHomo sapiens (human)
cytoplasmTubulin beta-1 chainHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (39)

Assay IDTitleYearJournalArticle
AID568507Induction of NQO1 activity in mouse Hepa1c1c7 cells assessed as concentration required to twofold increase of NQO1 activity at IC50 concentration relative to control2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Methoxylation of resveratrol: effects on induction of NAD(P)H quinone-oxidoreductase 1 (NQO1) activity and growth inhibitory properties.
AID214184Percentage inhibition of colchicine binding to tubulin by compound was evaluated1998Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
Antineoplastic agents. 379. Synthesis of phenstatin phosphate.
AID568508Cytotoxicity against mouse Hepa-1c1c7 cells after 24 hrs by MTT assay2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Methoxylation of resveratrol: effects on induction of NAD(P)H quinone-oxidoreductase 1 (NQO1) activity and growth inhibitory properties.
AID273358Inhibition of [3H]colchicine binding to tubulin at 5 uM2006Journal of medicinal chemistry, Oct-19, Volume: 49, Issue:21
2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
AID228455Inhibition of tubulin polymerization1992Journal of medicinal chemistry, Jun-12, Volume: 35, Issue:12
Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.
AID106876Cytotoxic concentration required to inhibit 50% cell growth in MLM melanoma cell lines1991Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
AID214546Concentration required to inhibit polymerization of tubulin2001Bioorganic & medicinal chemistry letters, Apr-09, Volume: 11, Issue:7
Novel sulfonate analogues of combretastatin A-4: potent antimitotic agents.
AID310083Inhibition of tubulin polymerization2007Bioorganic & medicinal chemistry letters, Nov-15, Volume: 17, Issue:22
Conformationally restricted macrocyclic analogues of combretastatins.
AID273362Antiproliferative activity against human H460 cell line by methylene blue dye assay2006Journal of medicinal chemistry, Oct-19, Volume: 49, Issue:21
2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
AID273361Antiproliferative activity against human KB-VIN10 cell line by methylene blue dye assay2006Journal of medicinal chemistry, Oct-19, Volume: 49, Issue:21
2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
AID221962Compound was evaluated for cytotoxicity against human SKMEL-5 melanoma cell line.1992Journal of medicinal chemistry, Jun-12, Volume: 35, Issue:12
Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.
AID273365Antiproliferative activity against human MKN45 cell line by methylene blue dye assay2006Journal of medicinal chemistry, Oct-19, Volume: 49, Issue:21
2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
AID568517Selectivity ratio of IC50 for human IMR90 cells to IC50 for human MCF7 cells2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Methoxylation of resveratrol: effects on induction of NAD(P)H quinone-oxidoreductase 1 (NQO1) activity and growth inhibitory properties.
AID103367Cytotoxicity against human MCF-7 breast cancer cell line.1992Journal of medicinal chemistry, Jun-12, Volume: 35, Issue:12
Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.
AID273359Inhibition of tubulin polymerization2006Journal of medicinal chemistry, Oct-19, Volume: 49, Issue:21
2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
AID143037Concentration required to inhibit proliferation of Human lung carcinoma NCI-H460 cell line2001Bioorganic & medicinal chemistry letters, Apr-09, Volume: 11, Issue:7
Novel sulfonate analogues of combretastatin A-4: potent antimitotic agents.
AID221796Compound was evaluated for cytotoxicity against human A-549 non-small cell lung cancer cell line.1992Journal of medicinal chemistry, Jun-12, Volume: 35, Issue:12
Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.
AID294475Induction of quinone reductase activity in mouse Hepa 1c1c7 cells at 1 uM after 24 hrs relative to control2007European journal of medicinal chemistry, Jun, Volume: 42, Issue:6
Quinone reductase induction activity of methoxylated analogues of resveratrol.
AID568515Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Methoxylation of resveratrol: effects on induction of NAD(P)H quinone-oxidoreductase 1 (NQO1) activity and growth inhibitory properties.
AID214160The compound was tested for the concentration to inhibit 50% of tubulin polymerization.1998Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
Antineoplastic agents. 379. Synthesis of phenstatin phosphate.
AID241105Concentration required for 50% inhibition of tubulin polymerization2005Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2
Quantitative structure-activity relationship (5D-QSAR) study of combretastatin-like analogues as inhibitors of tubulin assembly.
AID9208Cytotoxic concentration required to inhibit 50% cell growth in A-549 lung carcinoma cell lines1991Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
AID568514Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Methoxylation of resveratrol: effects on induction of NAD(P)H quinone-oxidoreductase 1 (NQO1) activity and growth inhibitory properties.
AID202827Cytotoxic concentration required to inhibit 50% cell growth in SKMEL-5 melanoma cell lines1991Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
AID78625Concentration required to inhibit proliferation of multidrug resistant Human colon carcinoma HCT-15 cell line2001Bioorganic & medicinal chemistry letters, Apr-09, Volume: 11, Issue:7
Novel sulfonate analogues of combretastatin A-4: potent antimitotic agents.
AID273360Antiproliferative activity against human KB cell line by methylene blue dye assay2006Journal of medicinal chemistry, Oct-19, Volume: 49, Issue:21
2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
AID568518Selectivity ratio of IC50 for human IMR90 cells to IC50 for human HCT116 cells2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Methoxylation of resveratrol: effects on induction of NAD(P)H quinone-oxidoreductase 1 (NQO1) activity and growth inhibitory properties.
AID84127Cytotoxic concentration required to inhibit 50% cell growth in HT-29 colon adenocarcinoma cell lines1991Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
AID294470Cytotoxicity against mouse Hepa 1c1c7 cells assessed as cell viability at 1 uM after 24 hrs by MTT assay2007European journal of medicinal chemistry, Jun, Volume: 42, Issue:6
Quinone reductase induction activity of methoxylated analogues of resveratrol.
AID273364Antiproliferative activity against human TSGH stomach carcinoma cell line by methylene blue dye assay2006Journal of medicinal chemistry, Oct-19, Volume: 49, Issue:21
2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
AID273363Antiproliferative activity against human HT29 cell line by methylene blue dye assay2006Journal of medicinal chemistry, Oct-19, Volume: 49, Issue:21
2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
AID221950Cytotoxicity against human MLM melanoma cell line.1992Journal of medicinal chemistry, Jun-12, Volume: 35, Issue:12
Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.
AID214171Effect on the binding of radiolabeled [3H]colchicine to tubulin1991Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
AID221812Cytotoxicity against human HT-29 colon cell line.1992Journal of medicinal chemistry, Jun-12, Volume: 35, Issue:12
Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.
AID42665Ability to inhibit Tubulin polymerization in Bovine brain1991Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
AID214032In vitro inhibition of bovine electrophoretically homogeneous tubulin polymerization.1993Journal of medicinal chemistry, Sep-17, Volume: 36, Issue:19
Synthesis and evaluation of a series of benzylaniline hydrochlorides as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization.
AID103262Cytotoxic concentration required to inhibit 50% cell growth in MCF-7 breast carcinoma cell lines1991Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.
AID568516Cytotoxicity against human IMR90 cells after 24 hrs by MTT assay2011Bioorganic & medicinal chemistry letters, Feb-01, Volume: 21, Issue:3
Methoxylation of resveratrol: effects on induction of NAD(P)H quinone-oxidoreductase 1 (NQO1) activity and growth inhibitory properties.
AID1801525Tyrosinase Activity from Article 10.1016/j.bioorg.2016.01.001: \\Synthesis and tyrosinase inhibition activity of trans-stilbene derivatives.\\2016Bioorganic chemistry, Feb, Volume: 64Synthesis and tyrosinase inhibition activity of trans-stilbene derivatives.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (39)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's4 (10.26)18.2507
2000's10 (25.64)29.6817
2010's21 (53.85)24.3611
2020's4 (10.26)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.82

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.82 (24.57)
Research Supply Index3.43 (2.92)
Research Growth Index5.25 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.82)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Observational0 (0.00%)0.25%
Other30 (100.00%)84.16%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]