Page last updated: 2024-12-08

1-(3-(dimethylamino)propyl)-5-methyl-3- phenyl-1h-indazole

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

You're describing a chemical compound, **1-(3-(dimethylamino)propyl)-5-methyl-3-phenyl-1H-indazole**. While it's a mouthful, let's break down why this might be important for research:

**1. Structure and Properties:**

* **Indazole Core:** The compound's core structure is an indazole ring, a five-membered aromatic ring fused to a benzene ring.
* **Substituents:** The indazole ring is adorned with specific substituents:
* **5-Methyl:** A methyl group (CH3) attached at the 5th position.
* **3-Phenyl:** A phenyl group (C6H5) attached at the 3rd position.
* **1-(3-(Dimethylamino)propyl):** A propyl chain with a dimethylamino group (N(CH3)2) at the end, attached at the 1st position.

**2. Potential Applications:**

* **Pharmacology:** The presence of the dimethylamino group and the indazole core suggests this compound might have pharmacological activity.
* **Ligand Binding:** Indazoles are known to bind to various receptors and enzymes. The specific substituents could influence its binding affinity and selectivity.
* **Biological Activity:** The dimethylamino group is a common feature in compounds with diverse biological effects, such as antihistamines, anticholinergics, and antidepressants.

**3. Research Significance:**

The compound's structure and potential biological activity make it a candidate for:

* **Drug Discovery:** Researchers might be exploring this compound or related analogues as potential therapeutic agents for various diseases.
* **Biological Studies:** It could serve as a tool to investigate the roles of specific receptors or enzymes in biological processes.
* **Material Science:** Indazoles can exhibit interesting optical and electronic properties, making them useful for materials science applications.

**Need for More Information:**

To fully understand the importance of this specific compound, we'd need more information, such as:

* **Research Focus:** What specific biological targets or applications are being investigated?
* **Synthesis and Characterization:** How is the compound synthesized and characterized?
* **Preclinical Data:** What are the preliminary results regarding its biological activity and potential therapeutic effects?

**In conclusion, the compound 1-(3-(dimethylamino)propyl)-5-methyl-3-phenyl-1H-indazole exhibits structural features that make it a potential candidate for research in diverse fields like pharmacology, biology, and materials science. Further research is needed to fully understand its importance and potential applications.**

1-(3-(dimethylamino)propyl)-5-methyl-3- phenyl-1H-indazole: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID194036
SCHEMBL ID11838059
MeSH IDM0075296

Synonyms (10)

Synonym
fs-32
fs 32
1h-indazole-1-propanamine, n,n,5-trimethyl-3-phenyl-
57614-23-0
1-(3-(dimethylamino)propyl)-5-methyl-3-phenyl-1h-indazole
fs32
1-(3-(dimethylamino)propyl)-5-methyl-3- phenyl-1h-indazole
SCHEMBL11838059
DTXSID50206277
PD161022

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" FS-32 showed anti-reserpine activity in a dose-dependent manner, whereas imipramine exhibited a bell-shaped dose-response pattern."( Pharmacological studies on a new thymoleptic antidepressant, 1-[3-(dimethylamino)propyl]-5-methyl-3-phenyl-1H-indazole (FS-32).
Fujimura, Y; Ikeda, Y; Iwasaki, T; Koide, T; Matsushita, H; Nagashima, R; Shindo, M; Shiraki, Y; Suzuki, S; Takano, N, 1979
)
0.26
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.66 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]