Assay ID | Title | Year | Journal | Article |
AID1853674 | Antibacterial activity against Mycobacterium intracellulare ATCC 13950 in presence of clarithromycin by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853676 | Antibacterial activity against Mycobacterium avium ATCC 25921 in presence of spectinomycin by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853668 | Synergistic antibacterial activity against Mycobacterium smegmatis mc2 155 assessed as fold reduction in MIC value at 8 ug/ml in presence of clarithromycin by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1616727 | Agonist activity at SNAP-tagged human D2LR expressed in Flp-In CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation at 10 uM measured after 10 mins in presence of coelenterazine by BRET assay relative to control | | | |
AID1616723 | Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assay | | | |
AID1853649 | Antibacterial activity against Mycobacterium smegmatis mc2 155 assessed as inhibition of bacterial growth incubated upto 3 weeks hrs by resazurin dye based double-dilution method | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853637 | Inhibition of Mycobacterium tuberculosis Eis assessed as Eis-mediated kanamycin acetylation preincubated for 10 mins followed by substrate addition and measured for 2 to 5 mins using acetyl-CoA as substrate in presence of kanamycin by UV-Vis spectroscopy | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853681 | Antibacterial activity against Mycobacterium bovis BCG ATCC 35734 in presence of clarithromycin by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID297276 | Displacement of [125I]HEAT from human recombinant adrenergic alpha-1A receptor | 2007 | Journal of medicinal chemistry, Aug-09, Volume: 50, Issue:16
| Synthesis and SAR investigations for novel melanin-concentrating hormone 1 receptor (MCH1) antagonists part 2: A hybrid strategy combining key fragments of HTS hits. |
AID297277 | Displacement of [3H]spiperone from human recombinant dopamine D2 receptor | 2007 | Journal of medicinal chemistry, Aug-09, Volume: 50, Issue:16
| Synthesis and SAR investigations for novel melanin-concentrating hormone 1 receptor (MCH1) antagonists part 2: A hybrid strategy combining key fragments of HTS hits. |
AID1616722 | Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes assessed as dissociation half-life by TR-FRET assay | | | |
AID1853648 | Inhibition of Mycobacterium tuberculosis AAC(2')-Ic at 200 uM using NEO as substrate in presence of Acetyl-CoA by UV-Vis spectroscopy analysis | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1616728 | Antagonist activity at SNAP-tagged human D2LR expressed in Flp-In CHO cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAMP accumulation at 10 uM preincubated with compound followed by forskolin and dopamine addition an | | | |
AID1853671 | Synergistic antibacterial activity against Mycobacterium abscessus ATCC 19977 in presence of clarithromycin by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853689 | Cytotoxicity against human A549 cells assessed as reduction in cell viability at 200 uM incubated for 24 hrs by resazurin assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853670 | Synergistic antibacterial activity against Mycobacterium abscessus ATCC 19977 assessed as reduction in bacterial growth presence of spectinomycin by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853678 | Antibacterial activity against Mycobacterium avium ATCC 25921 in presence of clarithromycin by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853675 | Antibacterial activity against Mycobacterium intracellulare ATCC 13950 in presence of clofazimine by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID297275 | Displacement of [3H]T-226296 from rat recombinant MCH1 receptor | 2007 | Journal of medicinal chemistry, Aug-09, Volume: 50, Issue:16
| Synthesis and SAR investigations for novel melanin-concentrating hormone 1 receptor (MCH1) antagonists part 2: A hybrid strategy combining key fragments of HTS hits. |
AID238112 | Binding affinity for Melanin-concentrating hormone 1 receptor expressed in CHO cells | 2004 | Journal of medicinal chemistry, Jul-29, Volume: 47, Issue:16
| A virtual screening approach to finding novel and potent antagonists at the melanin-concentrating hormone 1 receptor. |
AID1853651 | Antibacterial activity against Mycobacterium intracellulare ATCC 13950 assessed as inhibition of bacterial growth incubated upto 3 weeks hrs by resazurin dye based double-dilution method | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853673 | Antibacterial activity against Mycobacterium intracellulare ATCC 13950 in presence of spectinomycin by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853667 | Synergistic antibacterial activity against Mycobacterium smegmatis mc2 155 assessed as fold reduction in MIC value at 8 ug/ml in presence of spectinomycin by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853650 | Antibacterial activity against Mycobacterium abscessus ATCC 19977 assessed as inhibition of bacterial growth incubated upto 3 weeks hrs by resazurin dye based double-dilution method | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1616720 | Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes assessed as association rate constant by TR-FRET assay | | | |
AID1853647 | Inhibition of Mycobacterium tuberculosis AAC(3')-IV at 200 uM using NEO as substrate in presence of Acetyl-CoA by UV-Vis spectroscopy analysis | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853679 | Antibacterial activity against Mycobacterium avium ATCC 25921 in presence of clofazimine by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1616721 | Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes assessed as dissociation rate constant by TR-FRET assay | | | |
AID1853652 | Antibacterial activity against Mycobacterium avium ATCC 25921 assessed as inhibition of bacterial growth incubated upto 3 weeks hrs by resazurin dye based double-dilution method | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853680 | Synergistic antibacterial activity against Mycobacterium bovis BCG ATCC 35734 in presence of spectinomycin by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853686 | Cytotoxicity against human HEK293 cells assessed as reduction in cell viability at 200 uM incubated for 24 hrs by resazurin assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853683 | Synergistic antibacterial activity against Mycobacterium tuberculosis H37Ra ATCC NRS22 in presence of spectinomycin by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853654 | Antibacterial activity against Mycobacterium tuberculosis H37Ra ATCC NRS22 assessed as inhibition of bacterial growth incubated upto 3 weeks hrs by resazurin dye based double-dilution method | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853646 | Inhibition of Mycobacterium tuberculosis AAC(6')-Ie/APH(2'')-Ia assessed as inhbition at AAC(6')-Ie at 200 uM using NEO as substrate in presence of Acetyl-CoA by UV-Vis spectroscopy analysis | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853672 | Synergistic antibacterial activity against Mycobacterium abscessus ATCC 19977 in presence of clofazimine by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853669 | Synergistic antibacterial activity against Mycobacterium smegmatis mc2 155 assessed as fold reduction in MIC value at 8 ug/ml in presence of clofazimine by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853655 | Antibacterial activity against Mycobacterium tuberculosis mc2 6230 with Eis C-14T mutation assessed as inhibition of bacterial growth incubated upto 3 weeks hrs by resazurin dye based double-dilution method | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853682 | Antibacterial activity against Mycobacterium bovis BCG ATCC 35734 in presence of clofazimine by checkerboard assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853653 | Antibacterial activity against Mycobacterium bovis BCG ATCC 35734 assessed as inhibition of bacterial growth incubated upto 3 weeks hrs by resazurin dye based double-dilution method | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
AID1853691 | Cytotoxicity against mouse J774.A1 cells assessed as reduction in cell viability at 50 uM incubated for 24 hrs by resazurin assay | 2021 | RSC medicinal chemistry, Nov-17, Volume: 12, Issue:11
| Structure-based design of haloperidol analogues as inhibitors of acetyltransferase Eis from |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |