Page last updated: 2024-12-07

1-(2-(diphenylmethoxy)ethyl)-4-(2-(4-azido-3-iodophenyl)ethyl)piperazine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

The compound you described, **1-(2-(diphenylmethoxy)ethyl)-4-(2-(4-azido-3-iodophenyl)ethyl)piperazine**, is a complex organic molecule with several interesting features, making it potentially useful for research in various fields. Let's break it down:

**Structure and Features:**

* **Piperazine Core:** The molecule is built around a piperazine ring, a six-membered heterocyclic ring containing two nitrogen atoms. This ring is commonly found in pharmaceuticals, often acting as a scaffold for binding to biological targets.
* **Diphenylmethoxy Ethyl Group:** This bulky substituent is likely attached to the piperazine ring, potentially influencing the molecule's solubility and its interaction with biological membranes.
* **Azido and Iodo Substituents:** The presence of an azide group (N3) and an iodine atom on the phenyl ring hints at potential applications in photochemistry and radiochemistry. Azides are known to undergo photochemical reactions, and iodine isotopes can be used for labeling and imaging purposes.

**Potential Research Applications:**

* **Drug Discovery:** The combination of a piperazine ring with various substituents suggests a potential for this molecule to be a lead compound for developing new drugs. It might target specific receptors or enzymes involved in various biological processes.
* **Bioconjugation:** The azide group can participate in click chemistry reactions, allowing for the attachment of other functional groups or biomolecules, like peptides or fluorescent tags. This opens possibilities for developing targeted delivery systems for drugs or imaging probes.
* **Radiolabeling:** The iodine atom can be radiolabeled with iodine isotopes like iodine-125, making it a potential radiotracer for diagnostic imaging or therapeutic applications.

**Importance for Research:**

The importance of this compound lies in its unique combination of features, which opens the door to various research possibilities across different disciplines, including:

* **Medicinal Chemistry:** Developing new drug candidates with specific therapeutic targets.
* **Biochemistry:** Studying the interaction of the molecule with biological systems and identifying potential targets.
* **Materials Science:** Exploring its potential for developing novel biomaterials or delivery systems.
* **Radiochemistry:** Investigating its suitability for radiolabeling and its applications in imaging or therapy.

**Note:** It's essential to remember that this information is based on the structural features and general principles of chemistry. The actual properties and applications of this specific compound would need to be investigated further through detailed experimental studies.

If you have more context about the specific research area or purpose, I might be able to provide more specific and relevant information.

1-(2-(diphenylmethoxy)ethyl)-4-(2-(4-azido-3-iodophenyl)ethyl)piperazine: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

1-(2-(diphenylmethoxy)ethyl)-4-(2-(4-azido-3-iodophenyl)ethyl)piperazine : An N-alkylpiperazine that consists of piperazine bearing 2-(benzhydryloxy)ethyl and 2-(4-azido-3-iodophenyl)ethyl groups at positions 1 and 4 respectively. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID130012
MeSH IDM0168645

Synonyms (7)

Synonym
1-(2-(diphenylmethoxy)ethyl)-4-(2-(4-azido-3-iodophenyl)ethyl)piperazine
123632-48-4
1-[2-(2-azido-3-iodophenyl)ethyl]-4-(2-benzhydryloxyethyl)piperazine
piperazine, 1-(2-(2-azido-3-iodophenyl)ethyl)-4-(2-(diphenylmethoxy)ethyl)-
(125)i-deep
DTXSID30924563
1-[2-(2-azido-3-iodophenyl)ethyl]-4-[2-(diphenylmethoxy)ethyl]piperazine
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (12.50)18.7374
1990's7 (87.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.98

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.98 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index5.18 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.98)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]