(s-dinitrophenyl)-6-mercaptopurine riboside triphosphate

Description

The compound you're describing, **(s-dinitrophenyl)-6-mercaptopurine riboside triphosphate**, is a complex molecule with two main parts:

* **(s-dinitrophenyl):** This part is a chemical modification with a dinitrophenyl group attached to the molecule. Dinitrophenyl groups are known to be bulky and can interfere with interactions with other molecules.
* **6-mercaptopurine riboside triphosphate:** This is the core structure, which is a nucleotide. It consists of 6-mercaptopurine, a purine analog that can interfere with DNA synthesis and cell division, attached to a ribose sugar and three phosphate groups.

**This specific compound is likely designed for research purposes, as it combines the following properties:**

* **Inhibition of DNA synthesis:** The 6-mercaptopurine part can act as an inhibitor of DNA synthesis by interfering with the enzymatic activity of enzymes involved in DNA replication.
* **Modification for specific targeting:** The dinitrophenyl group might be used to introduce a specific binding property to the molecule, potentially allowing it to bind to a particular target within the cell. This could be useful for studying the mechanisms of DNA synthesis, targeting specific pathways, or developing novel therapeutic agents.

**Why is it important for research?**

The compound can be used in various research fields:

* **Cancer research:** By interfering with DNA synthesis, it could have potential as an anticancer agent.
* **Immunology:** It could be used to study the role of DNA synthesis in immune responses.
* **Drug development:** This compound could be a starting point for developing novel drugs that target specific pathways or enzymes involved in DNA replication.

**However, without further context, it's difficult to determine the exact application of this compound in research.** Its significance depends on its specific properties and the research questions being addressed.

To get a more accurate understanding of its importance, you would need to consult the specific research paper or project where it is mentioned.

(S-dinitrophenyl)-6-mercaptopurine riboside triphosphate: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]