Assay ID | Title | Year | Journal | Article |
AID678669 | Ratio of biodistribution in olfactory bulbs to striatum of in naive Wistar rat at 1 to 3 MBq, iv using [18F] labeled compound measured 30 mins post dose | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18
| Exploration of the structure-activity relationship of the diaryl anilide class of ligands for translocator protein--potential novel positron emitting tomography imaging agents. |
AID678668 | Biodistribution in naive Wistar rat olfactory bulbs at 1 to 3 MBq, iv using [18F] labeled compound measured 30 mins post dose | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18
| Exploration of the structure-activity relationship of the diaryl anilide class of ligands for translocator protein--potential novel positron emitting tomography imaging agents. |
AID644069 | Biodistribution in Sprague-Dawley rat olfactory bulbs at 1 to 3 MBq, iv after 30 mins by gamma counting | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3
| [¹⁸F]GE-180: a novel fluorine-18 labelled PET tracer for imaging Translocator protein 18 kDa (TSPO). |
AID644068 | Biodistribution in Sprague-Dawley rat whole brain at 1 to 3 MBq, iv after 2 mins by gamma counting | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3
| [¹⁸F]GE-180: a novel fluorine-18 labelled PET tracer for imaging Translocator protein 18 kDa (TSPO). |
AID644071 | Ratio of drug uptake in striatum in Sprague-Dawley rat at 1 to 3 MBq, iv after 2 mins to drug uptake in striatum in Sprague-Dawley rat at 1 to 3 MBq, iv after 30 mins | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3
| [¹⁸F]GE-180: a novel fluorine-18 labelled PET tracer for imaging Translocator protein 18 kDa (TSPO). |
AID678671 | Stability in naive Wistar rat brain assessed as parent compound level at 1 to 3 MBq, iv using [18F] labeled compound measured 60 mins post dose | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18
| Exploration of the structure-activity relationship of the diaryl anilide class of ligands for translocator protein--potential novel positron emitting tomography imaging agents. |
AID613586 | Drug uptake in rat striatum after 1-2 mins post injection | 2011 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 21, Issue:16
| Synthesis of 6-[¹⁸F]fluoro-PBR28, a novel radiotracer for imaging the TSPO 18 kDa with PET. |
AID644072 | Metabolic stability in Sprague-Dawley rat brain assessed as compound remaining at 1 to 3 MBq, iv after 60 mins by HPLC analysis | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3
| [¹⁸F]GE-180: a novel fluorine-18 labelled PET tracer for imaging Translocator protein 18 kDa (TSPO). |
AID744030 | Biodistribution in Wistar rat whole brain after 2 mins | 2013 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 23, Issue:8
| Exploration of the structure-activity relationship of a novel tetracyclic class of TSPO ligands-potential novel positron emitting tomography imaging agents. |
AID744028 | Biodistribution in Wistar rat brain after 30 mins | 2013 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 23, Issue:8
| Exploration of the structure-activity relationship of a novel tetracyclic class of TSPO ligands-potential novel positron emitting tomography imaging agents. |
AID678667 | Biodistribution in naive Wistar rat whole brain at 1 to 3 MBq, iv using [18F] labeled compound measured 2 mins post dose | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18
| Exploration of the structure-activity relationship of the diaryl anilide class of ligands for translocator protein--potential novel positron emitting tomography imaging agents. |
AID644070 | Ratio of drug uptake in olfactory bulb to striatum in Sprague-Dawley rat at 1 to 3 MBq, iv after 30 mins by gamma counting | 2012 | Bioorganic & medicinal chemistry letters, Feb-01, Volume: 22, Issue:3
| [¹⁸F]GE-180: a novel fluorine-18 labelled PET tracer for imaging Translocator protein 18 kDa (TSPO). |
AID678670 | Ratio of biodistribution in striatum at 2 mins post dose to biodistribution in striatum post 30 mins in naive Wistar rat at 1 to 3 MBq, iv using [18F] labeled compound | 2012 | Bioorganic & medicinal chemistry letters, Sep-15, Volume: 22, Issue:18
| Exploration of the structure-activity relationship of the diaryl anilide class of ligands for translocator protein--potential novel positron emitting tomography imaging agents. |
AID613585 | Drug uptake in AMPA lesioned rat striatum after 1-2 mins post injection | 2011 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 21, Issue:16
| Synthesis of 6-[¹⁸F]fluoro-PBR28, a novel radiotracer for imaging the TSPO 18 kDa with PET. |
AID744027 | Ratio of drug uptake in Wistar rat brain to Wistar rat striatum after 30 mins | 2013 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 23, Issue:8
| Exploration of the structure-activity relationship of a novel tetracyclic class of TSPO ligands-potential novel positron emitting tomography imaging agents. |
AID744026 | Ratio of drug uptake in Wistar rat striatum after 2 mins to Wistar rat striatum after 30 mins | 2013 | Bioorganic & medicinal chemistry letters, Apr-15, Volume: 23, Issue:8
| Exploration of the structure-activity relationship of a novel tetracyclic class of TSPO ligands-potential novel positron emitting tomography imaging agents. |
AID1076458 | Ratio of drug level from ipsilateral to contralateral in Wistar rat administered as iv measured after 60 mins of postinjection by MicroPET imaging analysis | 2014 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 24, Issue:6
| Preparation and evaluation of novel pyrazolo[1,5-a]pyrimidine acetamides, closely related to DPA-714, as potent ligands for imaging the TSPO 18kDa with PET. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |