(4-nitrophenyl)vinyl ether

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

While detailed information on the specific synthesis, effects, and importance of (4-nitrophenyl)vinyl ether is scarce in readily available research databases, its structure suggests potential for applications in organic synthesis and material science. The nitro group on the phenyl ring imparts electron-withdrawing properties, which could make the compound a useful building block for creating functionalized molecules. The vinyl ether functionality is also known for its reactivity, potentially leading to its use in various chemical transformations. Further investigation into the properties and applications of (4-nitrophenyl)vinyl ether is necessary to fully understand its potential.'

Cross-References

ID Source	ID
PubMed CID	119042
SCHEMBL ID	830158
MeSH ID	M0137584

Synonyms (21)

Synonym
ccris 2897
ether, p-nitrophenyl vinyl
(4-nitrophenyl)vinyl ether
p-nitrophenyl vinyl ether
1-(ethenyloxy)-4-nitrobenzene
4-nitrophenyl vinyl ether
vinyl p-nitrophenyl ether
benzene, 1-(ethenyloxy)-4-nitro-
inchi=1/c8h7no3/c1-2-12-8-5-3-7(4-6-8)9(10)11/h2-6h,1h
940-14-7
1-ethenoxy-4-nitrobenzene
AKOS006278228
1-nitro-4-(vinyloxy)benzene
ba6lq39mhh ,
(para-nitrophenyl)vinyl ether
unii-ba6lq39mhh
SCHEMBL830158
DTXSID90240190
1-nitro-4-vinyloxy-benzene
CS-0242227
EN300-246227

Research Excerpts

Toxicity

Excerpt	Reference	Relevance
" These results showed that aryl vinyl ethers, NPVE and PVE, are more toxic than the alkyl vinyl ether, BVE, and that glutathione plays an important role on the protection of hepatic injury by reactive metabolite(s) derived from vinyl ethers."	( Depletion of glutathione and hepato-toxicity caused by vinyl ethers in mice. Isobe, M; Sone, T; Takabatake, E, 1995)	0.29

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	2 (40.00)	18.7374
1990's	2 (40.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.46

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.46 (24.57)
Research Supply Index	1.79 (2.92)
Research Growth Index	4.25 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.46)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
4-nitrophenol 4-nitrophenol: RN given refers to parent cpd. mononitrophenol : A nitrophenol that is phenol carrying a single nitro substituent at unspecified position.. 4-nitrophenol : A member of the class of 4-nitrophenols that is phenol in which the hydrogen that is para to the hydroxy group has been replaced by a nitro group.	2	1	4-nitrophenols	human xenobiotic metabolite; mouse metabolite
urethane [no description available]	1.98	1	carbamate ester	fungal metabolite; mutagen
4-nitrophenetol [no description available]	2	1
n-butyl vinyl ether vinilin: RN given refers to cpd with unknown MF; no further information available 10/91	1.98	1
vinyl carbamate vinyl carbamate: promutagen & more carcinogenic analog of ethyl carbamate (urethane); structure	1.98	1	carbamate ester
nitrophenols Nitrophenols: PHENOLS carrying nitro group substituents.	2	1

Condition	Relationship Strength	Studies
Acute Liver Injury, Drug-Induced [description not available]	1.98	1
Chemical and Drug Induced Liver Injury A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.	1.98	1
Papilloma, Squamous Cell [description not available]	1.98	1
Cancer of Skin [description not available]	1.98	1
Papilloma A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)	1.98	1
Skin Neoplasms Tumors or cancer of the SKIN.	1.98	1

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