(4-benzylpiperidin-1-yl)-(6-hydroxy-1h-indol-2-yl)methanone

Description

(4-Benzylpiperidin-1-yl)-(6-hydroxy-1H-indol-2-yl)methanone is a **synthetic compound** with the chemical formula **C23H24N2O2**. It is a **derivative of indole**, a naturally occurring compound found in many plants and animals.

**Its significance in research stems from its potential biological activity:**

* **Serotonin Receptor Agonism:** This compound has shown affinity for serotonin receptors, particularly 5-HT1A receptors. Serotonin is a neurotransmitter that plays a vital role in mood regulation, sleep, appetite, and other functions. Targeting these receptors is of interest for developing drugs to treat conditions like anxiety and depression.
* **Potential Anti-Cancer Activity:** Some research suggests that this compound might have anti-cancer properties. This is due to its ability to inhibit the growth of certain cancer cell lines, potentially by interfering with cell signaling pathways.
* **Anti-Inflammatory Properties:** Initial studies indicate that this compound may possess anti-inflammatory activity. This is a promising area of investigation, as inflammation is implicated in various diseases.

**However, it is important to note that:**

* **Research is still ongoing:** The compound is relatively new, and much research is still needed to understand its full biological profile, its safety, and its potential therapeutic applications.
* **Clinical Trials are Necessary:** Before any potential benefits can be realized in humans, extensive clinical trials are necessary to assess its efficacy, safety, and optimal dosing.

**In summary, (4-benzylpiperidin-1-yl)-(6-hydroxy-1H-indol-2-yl)methanone is a promising compound with potential for therapeutic applications, particularly in the areas of neuropsychiatric disorders, cancer, and inflammation. However, much more research is required before it can be considered for clinical use.**

(4-benzylpiperidin-1-yl)-(6-hydroxy-1H-indol-2-yl)methanone: an NR2B-subunit selective antagonist; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]