Page last updated: 2024-12-07

(3-isocyanatopropyl) triethoxysilane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

(3-Isocyanatopropyl) triethoxysilane, also known as **IPTS**, is a versatile organosilane compound that is commonly used in research and industrial applications.

Here's a breakdown:

**Structure and Properties:**

* **Structure:** IPTS has a triethoxysilane group (Si(OCH2CH3)3) at one end and an isocyanate group (-N=C=O) at the other end. This unique structure allows for versatile chemical reactions and applications.
* **Reactivity:** The isocyanate group is highly reactive and can readily react with various functional groups, such as alcohols, amines, and water. This reactivity is key to IPTS's diverse applications.
* **Hydrolyzable:** The triethoxysilane group can hydrolyze in the presence of moisture, forming silanol groups (Si-OH). These silanol groups can then condense with other silanol groups, forming strong Si-O-Si bonds.

**Importance in Research and Applications:**

IPTS is a valuable compound in various research areas and industrial applications, primarily due to its ability to:

* **Form durable coatings:** IPTS can be used to create durable coatings on various surfaces, including glass, metals, and plastics. The hydrolysis of the silane group and subsequent condensation lead to strong siloxane bonds, forming a robust protective layer.
* **Act as a coupling agent:** IPTS can act as a coupling agent, linking organic and inorganic materials together. This property is crucial in creating composite materials, improving adhesion between different materials, and enhancing the performance of various products.
* **Synthesize new materials:** IPTS can be used as a building block to synthesize new materials with tailored properties, such as hydrophobicity, adhesion, and surface modification.
* **Promote polymerization:** The isocyanate group in IPTS can participate in polymerization reactions, forming polyurethane polymers with a range of applications.

**Specific Research Areas:**

* **Surface modification:** IPTS is frequently used to modify surface properties, making materials more hydrophobic, resistant to wear, or compatible with specific applications.
* **Biomedical engineering:** IPTS plays a role in developing biocompatible materials for tissue engineering, drug delivery systems, and biosensors.
* **Nanocomposites:** IPTS is used to create nanocomposites, enhancing the mechanical, electrical, and optical properties of materials.

**Overall, (3-isocyanatopropyl) triethoxysilane is a crucial reagent for various research and industrial applications due to its versatility, reactivity, and ability to form strong bonds and create novel materials.**

(3-isocyanatopropyl) triethoxysilane: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID90613
CHEMBL ID3187620
SCHEMBL ID47858
MeSH IDM0474076

Synonyms (59)

Synonym
3-isocyanatopropyltriethoxysilane
einecs 246-467-6
i 7840
yh 9030
isocyanatopropyltriethoxysilane
silane, triethoxy(3-isocyanatopropyl)-
y 9030
isocyanic acid, 3-(triethoxysilyl)propyl ester
isocyanic acid, 3-(triethoxysilyl)propylester
triethoxy(3-isocyanatopropyl)silane
c10h21no4si
3-(triethoxysilyl)propyl isocyanate, 95%
24801-88-5
STK802173
cas-24801-88-5
NCGC00255560-01
tox21_302179
dtxcid2018847
dtxsid4038847 ,
A817497
3-(triethoxysilyl)propyl isocyanate
I0556
(3-isocyanatopropyl)triethoxysilane
icptes
isocyanic acid 3-(triethoxysilyl)propyl ester
AKOS015918140
9br6002p6e ,
ec 246-467-6
unii-9br6002p6e
FT-0604711
SCHEMBL47858
BBL028027
gamma-triethoxysilylpropyl isocyanate
ocn(ch2)3si(och2ch3)3
3-triethoxysilanylpropyl isocyanate
3-isocyanatopropyl(triethoxysilane)
(3-isocyanatopropyl) triethoxysilane
3-isocyanatopropyltriethoxy silane
3-isocyanatopropyl-triethoxysilane
(.gamma.-isocyanatopropyl)triethoxysilane
.gamma.-isocyanopropyltriethoxysilane
3-isocyananopropyltriethoxysilane
triethoxysilylpropyl isocyanate
triethoxy(.gamma.-isocyanatopropyl)silane
1-(triethoxysilyl)-3-isocyanatopropane
.gamma.-(triethoxysilyl)propyl isocyanate
3-(isocyanopropyl)triethoxysilane
CHEMBL3187620
J-512715
mfcd00051459
triethoxy(3-isocyanatopropyl)silane, purum, >=95.0% (gc)
AS-14914
3-(triethoxysilyl)-propyl isocyanate
3-(triethoxysilyl)propylisocyanate
Q27272327
153487-51-5
3-iscyanatopropyltriethoxysilane
(3-iscyanatopropyl)triethoxysilane
EN300-704092
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (3)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
estrogen nuclear receptor alphaHomo sapiens (human)Potency68.58960.000229.305416,493.5996AID1259244
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency68.58960.001557.789015,848.9004AID1259244
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency68.58960.001551.739315,848.9004AID1259244
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Ceullar Components (1)

Processvia Protein(s)Taxonomy
plasma membraneGlutamate receptor 2Rattus norvegicus (Norway rat)
[Information is prepared from geneontology information from the June-17-2024 release]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 28.10

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index28.10 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index31.58 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (28.10)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]