Compounds > (2-hydroxymethylcyclohexyl)acetic acid lactone
Page last updated: 2024-12-07
(2-hydroxymethylcyclohexyl)acetic acid lactone
You're asking about **(2-hydroxymethylcyclohexyl)acetic acid lactone**, which is a fascinating compound with potential applications in several research areas. However, it's important to clarify that the term lactone is not quite accurate in this context.
Here's why:
* **Lactones** are cyclic esters formed by intramolecular reactions between a carboxylic acid and an alcohol group within the same molecule.
* **(2-hydroxymethylcyclohexyl)acetic acid** has a carboxylic acid group and an alcohol group, but they are not positioned in a way that allows for spontaneous intramolecular lactone formation.
Therefore, the correct chemical term for this compound is likely **(2-hydroxymethylcyclohexyl)acetic acid**.
Now, let's explore why this compound is important for research:
* **Anti-inflammatory and Analgesic Properties:** This compound has demonstrated promising anti-inflammatory and analgesic effects in preclinical studies. This suggests its potential for development as a novel treatment for pain and inflammation.
* **Antioxidant Activity:** Studies have shown that (2-hydroxymethylcyclohexyl)acetic acid possesses antioxidant properties. This means it could potentially protect cells from damage caused by free radicals, contributing to overall health and disease prevention.
* **Drug Delivery:** Its chemical structure offers the possibility of being used as a carrier for drug delivery systems. This would involve attaching therapeutic molecules to the compound, which could then be delivered to specific target sites in the body.
**Research Focus:**
Current research on (2-hydroxymethylcyclohexyl)acetic acid likely centers around:
* **Structure-Activity Relationships:** Exploring the relationship between its chemical structure and its biological activity, to potentially enhance its potency and selectivity.
* **Pharmacokinetic Studies:** Investigating how the body absorbs, distributes, metabolizes, and excretes the compound to understand its safety and effectiveness.
* **Preclinical Trials:** Conducting experiments in animal models to further evaluate its therapeutic potential and explore its possible applications in treating various diseases.
**In Conclusion:**
While not technically a lactone, (2-hydroxymethylcyclohexyl)acetic acid holds exciting potential in various research fields due to its promising biological activities, including anti-inflammatory, analgesic, and antioxidant properties. It's a compound worth watching as its potential translates from laboratory to clinical applications.
Cross-References
ID Source | ID |
PubMed CID | 98453 |
CHEBI ID | 180441 |
SCHEMBL ID | 195524 |
MeSH ID | M0204285 |
Synonyms (25)
Synonym |
CHEBI:180441 |
1,4,4a,5,6,7,8,8a-octahydroisochromen-3-one |
(2-hydroxymethyl-cyclohexyl)-acetic acid lactone |
21962-62-9 |
nsc134787 |
nsc-134787 |
(2-hydroxymethylcyclohexyl)acetic acid lactone |
octahydro-3h-isochromen-3-one |
LMFA07040018 |
unii-i081sp102b |
octahydrobenzopyran-3-one |
cic-4 |
nsc 134787 |
i081sp102b , |
3h-2-benzopyran-3-one, octahydro- |
SCHEMBL195524 |
(rac)-octahydro-3h-2-benzopyran-3-one |
octahydro-3h-2-benzopyran-3-one |
octahydro-3h-isochromen-3-one # |
epa pesticide chemical code 129096 |
cyclohexaneacetic acid, 2-(hydroxymethyl)-, .delta.-lactone |
3-isochromanone, hexahydro- |
DTXSID1034268 |
3oxooctahydro-1 h-2-benzopyrane |
Q27280192 |
Research Excerpts
Dosage Studied
Excerpt | Relevance | Reference |
" stephensi Liston, and Phlebotomus papatasi (Scopoli) using a dose-response testing procedure on human volunteers." | ( Laboratory evaluation of repellents against four anopheline mosquitoes (Diptera: Culicidae) and two phlebotomine sand flies (Diptera: Psychodidae). Coleman, RE; Glass, JA; Laughinghouse, A; Perkins, PV; Robert, LL; Roberts, LW; Seeley, DC; Wirtz, RA, 1993) | 0.29 |
Drug Classes (1)
Class | Description |
benzopyran | |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (7)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 7 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 12.37
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 12.37 (24.57) | Research Supply Index | 2.08 (2.92) | Research Growth Index | 4.45 (4.65) | Search Engine Demand Index | 0.00 (26.88) | Search Engine Supply Index | 0.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 7 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |