Compounds > (2-cyano-3-(methylamino)phenyl)oxoacetic acid sodium salt
Page last updated: 2024-11-13

(2-cyano-3-(methylamino)phenyl)oxoacetic acid sodium salt

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

(2-cyano-3-(methylamino)phenyl)oxoacetic acid: orally active antiallergy agent; RN given is for Na salt [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID23689136
CHEMBL ID349926
SCHEMBL ID11634616
MeSH IDM0098462

Synonyms (14)

Synonym
((2-cyano-3-(methylamino)phenyl)amino)oxoacetic acid monosodium salt
wy 41195
acetic acid, ((2-cyano-3-(methylamino)phenyl)amino)oxo-, monosodium salt
wy-41195
CHEMBL349926
63365-44-6
unii-wh6c1ntp45
wh6c1ntp45 ,
(2-cyano-3-(methylamino)phenyl)oxoacetic acid
SCHEMBL11634616
DTXSID10979511
sodium [2-cyano-3-(methylamino)anilino](oxo)acetate
Q27292639
sodium;2-[2-cyano-3-(methylamino)anilino]-2-oxoacetate
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID185434Percent inhibition using passive cutaneous anaphylaxis (PCA assay) in rat at 1 mg/kg upon oral administration1981Journal of medicinal chemistry, Jun, Volume: 24, Issue:6
N-(aminophenyl)oxamic acids and esters as potent, orally active antiallergy agents.
AID178115Antiallergic property in passive cutaneous anaphylaxis (PCA) test in rats upon oral administration1981Journal of medicinal chemistry, Jun, Volume: 24, Issue:6
N-(aminophenyl)oxamic acids and esters as potent, orally active antiallergy agents.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.50 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (16.67%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (83.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
oxamic acid
Oxamic Acid: Amino-substituted glyoxylic acid derivative.. oxamic acid : A dicarboxylic acid monoamide resulting from the formal condensation of one of the carboxy groups of oxalic acid with ammonia.		4.3160dicarboxylic acid monoamideEscherichia coli metabolite
sulfur dioxide
Sulfur Dioxide: A highly toxic, colorless, nonflammable gas. It is used as a pharmaceutical aid and antioxidant. It is also an environmental air pollutant.		1.9610sulfur oxideEscherichia coli metabolite;
food bleaching agent;
refrigerant
cromolyn sodium
Cromolyn Sodium: A chromone complex that acts by inhibiting the release of chemical mediators from sensitized MAST CELLS. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack.. disodium cromoglycate : An organic sodium salt that is the disodium salt of cromoglycic acid.		3.9840organic sodium saltanti-asthmatic drug;
drug allergen
ConditionIndicatedRelationship StrengthStudiesTrials
Allergic Reaction
[description not available]		02.3620
Hypersensitivity
Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.		02.3620
Muscle Contraction
A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.		01.9610
Asthma, Bronchial
[description not available]		03.2920
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.		01.9610
Atopic Hypersensitivity
[description not available]		01.9610
Asthma
A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).		03.2920