(2-chlorophenyl)-(5-hydroxy-3-methyl-5-phenyl-4H-pyrazol-1-yl)methanone is a complex organic molecule. While I don't have access to a database of specific chemical compounds or research findings, I can break down the information given and explain why it's important for research in general.
**Let's analyze the structure:**
* **(2-chlorophenyl)-(5-hydroxy-3-methyl-5-phenyl-4H-pyrazol-1-yl)methanone:**
* **(2-chlorophenyl):** This indicates a phenyl ring (a six-membered carbon ring with alternating single and double bonds) with a chlorine atom attached to the second carbon.
* **(5-hydroxy-3-methyl-5-phenyl-4H-pyrazol-1-yl):** This describes a pyrazole ring. Pyrazole is a five-membered ring containing two nitrogen atoms and a carbon. In this case, it has:
* A hydroxyl group (-OH) attached to the fifth carbon.
* A methyl group (-CH3) attached to the third carbon.
* A phenyl ring attached to the fifth carbon.
* The '4H' indicates the presence of a hydrogen atom on the fourth carbon.
* **methanone:** This is a ketone functional group (C=O).
**Why is it important for research?**
Many organic compounds with complex structures like this one are investigated for potential biological activity. This is because:
* **Pyrazoles:** These are frequently found in pharmaceuticals and agrochemicals. They possess diverse biological activities, including anti-inflammatory, analgesic, anti-microbial, and anti-cancer properties.
* **Ketones:** These are common functional groups that can influence a molecule's interaction with biological systems. They can also be modified for various applications.
* **Substituents:** The presence of chlorine, methyl, and phenyl groups adds to the compound's complexity and can influence its biological activity and physical properties.
**Potential Research Areas:**
The specific molecule you mentioned could be investigated for:
* **Pharmaceutical applications:** As a potential drug candidate for various diseases or conditions.
* **Agrochemical applications:** As a pesticide, herbicide, or fungicide.
* **Material science:** For its potential properties as a polymer, dye, or other material.
**Key takeaway:** Complex organic molecules like (2-chlorophenyl)-(5-hydroxy-3-methyl-5-phenyl-4H-pyrazol-1-yl)methanone are studied to explore their potential applications in medicine, agriculture, and other fields.
To find out more about the specific research related to this molecule, you would need to search for it in scientific databases such as PubMed, Web of Science, or Google Scholar.
ID Source | ID |
---|---|
PubMed CID | 2868929 |
CHEMBL ID | 1566760 |
CHEBI ID | 121655 |
Synonym |
---|
(2-chlorophenyl)-(5-hydroxy-3-methyl-5-phenyl-4h-pyrazol-1-yl)methanone |
CBMICRO_014078 |
5792-72-3 |
BIM-0014070.P001 |
EU-0010106 |
MLS001202722 |
smr000514891 |
(2-chloro-phenyl)-(5-hydroxy-3-methyl-5-phenyl-4,5-dihydro-pyrazol-1-yl)-methanone |
CHEBI:121655 |
AKOS000592116 |
STK868230 |
(2-chlorophenyl)(5-hydroxy-3-methyl-5-phenyl-4,5-dihydro-1h-pyrazol-1-yl)methanone |
CB09375 |
smsf0007837 |
HMS2816C10 |
AKOS021998678 |
CHEMBL1566760 |
DTXSID30386682 |
Q27210216 |
1-(2-chlorobenzoyl)-3-methyl-5-phenyl-4,5-dihydro-1h-pyrazol-5-ol |
Class | Description |
---|---|
carbonyl compound | Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives. |
organohalogen compound | A compound containing at least one carbon-halogen bond (where X is a halogen atom). |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
glp-1 receptor, partial | Homo sapiens (human) | Potency | 10.0000 | 0.0184 | 6.8060 | 14.1254 | AID624417 |
apical membrane antigen 1, AMA1 | Plasmodium falciparum 3D7 | Potency | 1.9953 | 0.7079 | 12.1943 | 39.8107 | AID720542 |
67.9K protein | Vaccinia virus | Potency | 7.9433 | 0.0001 | 8.4406 | 100.0000 | AID720579 |
P53 | Homo sapiens (human) | Potency | 70.7946 | 0.0731 | 9.6858 | 31.6228 | AID504706 |
chromobox protein homolog 1 | Homo sapiens (human) | Potency | 100.0000 | 0.0060 | 26.1688 | 89.1251 | AID540317 |
nuclear receptor ROR-gamma isoform 1 | Mus musculus (house mouse) | Potency | 6.6946 | 0.0079 | 8.2332 | 1,122.0200 | AID2546; AID2551 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | |||
AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7 | A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID1745845 | Primary qHTS for Inhibitors of ATXN expression | |||
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5 | Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1 | High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (20.00) | 29.6817 |
2010's | 3 (60.00) | 24.3611 |
2020's | 1 (20.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.56) All Compounds (24.57) |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 5 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |