Page last updated: 2024-12-07

(1-(5-dimethylaminonaphthalene)sulfonamido)-n-hexanoic acid-beta-n-trimethylammonium bromide ethyl ester

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

The compound you described, (1-(5-dimethylaminonaphthalene)sulfonamido)-n-hexanoic acid-beta-n-trimethylammonium bromide ethyl ester, is a complex molecule with a rather unwieldy name. Let's break down its structure and potential significance:

**Structure:**

* **(1-(5-dimethylaminonaphthalene)sulfonamido):** This part refers to a sulfonamide group (SO2NH2) attached to the 1-position of a 5-dimethylaminonaphthalene ring. This ring system is known as a dansyl group and is commonly used as a fluorescent tag in biochemistry.
* **-n-hexanoic acid:** A six-carbon carboxylic acid chain is attached to the sulfonamide group.
* **-beta-n-trimethylammonium bromide:** This part indicates that a trimethylammonium group (N(CH3)3+) is attached to the beta-carbon of the hexanoic acid chain. The bromide (Br-) is a counterion to balance the positive charge of the ammonium group.
* **ethyl ester:** The carboxyl group of the hexanoic acid is esterified with an ethyl group (CH3CH2-).

**Significance in Research:**

The combination of features in this molecule makes it a potential candidate for various research applications, particularly in the areas of:

* **Biochemistry and Molecular Biology:** The dansyl group can be used as a fluorescent probe to track or identify specific molecules or structures within cells. The presence of the trimethylammonium group might allow for interactions with negatively charged biomolecules like DNA or proteins.
* **Drug Development:** The combination of a fluorescent tag, a hydrophobic chain (hexanoic acid), and a charged group (trimethylammonium) could give this molecule properties that make it suitable for interacting with biological targets or cell membranes.
* **Material Science:** The molecule could potentially be used as a building block for self-assembling structures or as a component in biocompatible materials.

**Important Note:**

It is crucial to understand that without further context or specific information about the research goals, it is difficult to definitively determine the exact significance of this molecule. The research area and the specific experiments would influence the importance of this particular compound.

**Additional Steps:**

To find out more about this molecule, you would need to research the following:

* **Who synthesized it?** Is there any published research related to this molecule?
* **What are the intended applications?** Are there any patents or publications that discuss the use of this molecule?
* **What are the molecule's properties?** What are its solubility, stability, fluorescence characteristics, and other relevant properties?

By answering these questions, you can gain a deeper understanding of the potential role and importance of (1-(5-dimethylaminonaphthalene)sulfonamido)-n-hexanoic acid-beta-n-trimethylammonium bromide ethyl ester in research.

(1-(5-dimethylaminonaphthalene)sulfonamido)-n-hexanoic acid-beta-N-trimethylammonium ethyl ester: RN given refers to bromide [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID124728
MeSH IDM0090356

Synonyms (8)

Synonym
(1-(5-dimethylaminonaphthalene)sulfonamido)-n-hexanoic acid-beta-n-trimethylammonium ethyl ester
60837-35-6
dns-c6-cho
ethanaminium, 2-((6-(((5-(dimethylamino)-1-naphthalenyl)sulfonyl)amino)-1-oxohexyl)oxy)-n,n,n-trimethyl-
(1-(5-dimethylaminonaphthalene)sulfonamido)-n-hexanoic acid-beta-n-trimethylammonium bromide ethyl ester
dansyl-c6-choline
2-[(6-{[5-(dimethylamino)naphthalene-1-sulfonyl]amino}hexanoyl)oxy]-n,n,n-trimethylethan-1-aminium bromide
DTXSID70976309

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Dose-response curves for ouabain, a specific Na(+),K(+)-ATPase inhibitor, were obtained to ascertain which Na(+),K(+)-ATPase isoform(s) is involved."( On the functional interaction between nicotinic acetylcholine receptor and Na+,K+-ATPase.
Drabkina, TM; Eaton, MJ; Kravtsova, VV; Krivoi, II; Mandel, F; Skatchkov, SN; Vasiliev, AN, 2006
)
0.33
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (14)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (28.57)18.7374
1990's4 (28.57)18.2507
2000's6 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.68

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.68 (24.57)
Research Supply Index2.71 (2.92)
Research Growth Index4.39 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.68)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other14 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]