Assay ID | Title | Year | Journal | Article |
AID22008 | Compound was evaluated, at a concentration of 10 mM acid, the solubility ratio is obtained by dividing the solubility of sickle hemoglobin (HbS) with the compound (grams per deciliter) by the solubility of the untreated sample (grams per deciliter) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2
| Design, synthesis, and testing of potential antisickling agents. 3. Ethacrynic acid. |
AID22149 | Solubility ratio ([HbS+drug (5 mM)]/[HbS-drug]) | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| Design, synthesis, and testing of potential antisickling agents. 4. Structure-activity relationships of benzyloxy and phenoxy acids. |
AID22013 | Solubility ratio ([HbS+drug (20 mM)]/[HbS-drug] | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| Design, synthesis, and testing of potential antisickling agents. 4. Structure-activity relationships of benzyloxy and phenoxy acids. |
AID22010 | Compound was evaluated, at a concentration of 40 mM acid, the solubility ratio is obtained by dividing the solubility of sickle hemoglobin (HbS) with the compound (grams per deciliter) by the solubility of the untreated sample (grams per deciliter) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2
| Design, synthesis, and testing of potential antisickling agents. 3. Ethacrynic acid. |
AID19554 | Compound was evaluated, at a concentration of 10 mM acid, for its ability to increase the solubility of sickle hemoglobin | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2
| Design, synthesis, and testing of potential antisickling agents. 3. Ethacrynic acid. |
AID22148 | Solubility ratio ([HbS+drug (40 mM)]/[HbS-drug]) | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| Design, synthesis, and testing of potential antisickling agents. 4. Structure-activity relationships of benzyloxy and phenoxy acids. |
AID21143 | Solubility of Deoxyhemoglobin S (dHbS) concentration after addition dithionite as control | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| Design, synthesis, and testing of potential antisickling agents. 4. Structure-activity relationships of benzyloxy and phenoxy acids. |
AID21145 | Solubility of Haemoglobin S (HbS) concentration after addition of acid and dithionite | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| Design, synthesis, and testing of potential antisickling agents. 4. Structure-activity relationships of benzyloxy and phenoxy acids. |
AID19558 | Compound was evaluated, at a concentration of 5 mM acid, for its ability to increase the solubility of sickle hemoglobin | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2
| Design, synthesis, and testing of potential antisickling agents. 3. Ethacrynic acid. |
AID19555 | Compound was evaluated, at a concentration of 20 mM acid, for its ability to increase the solubility of sickle hemoglobin | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2
| Design, synthesis, and testing of potential antisickling agents. 3. Ethacrynic acid. |
AID19557 | Compound was evaluated, at a concentration of 40 mM acid, for its ability to increase the solubility of sickle hemoglobin | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2
| Design, synthesis, and testing of potential antisickling agents. 3. Ethacrynic acid. |
AID22011 | Compound was evaluated, at a concentration of 5 mM acid, the solubility ratio is obtained by dividing the solubility of sickle hemoglobin (HbS) with the compound (grams per deciliter) by the solubility of the untreated sample (grams per deciliter) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2
| Design, synthesis, and testing of potential antisickling agents. 3. Ethacrynic acid. |
AID22009 | Compound was evaluated, at a concentration of 20 mM acid, the solubility ratio is obtained by dividing the solubility of sickle hemoglobin (HbS) with the compound (grams per deciliter) by the solubility of the untreated sample (grams per deciliter) | 1984 | Journal of medicinal chemistry, Feb, Volume: 27, Issue:2
| Design, synthesis, and testing of potential antisickling agents. 3. Ethacrynic acid. |
AID22012 | Solubility ratio ([HbS+drug (10 mM)]/[HbS-drug]) | 1984 | Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
| Design, synthesis, and testing of potential antisickling agents. 4. Structure-activity relationships of benzyloxy and phenoxy acids. |
AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6
| A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | | | |
AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6
| A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |