Any oxolane having an oxo- substituent at any position on the tetrahydrofuran ring.
ChEBI ID: 47016
Member | Definition | Role |
---|---|---|
4-methylene-2-octyl-5-oxo-3-oxolanecarboxylic acid | A tetrahydrofuranone that is tetrahydrofuran substituted by octyl, carboxy, methylidene, and oxo groups at positions 2, 3, 4 and 5, respectively. | 4-methylene-2-octyl-5-oxo-3-oxolanecarboxylic acid; 4-methylidene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid |
ascofuranone | A dihydroxybenzaldehyde that is 2,4-dihydroxybenzaldehyde which is substituted by a (2E,6E)-7-[(2S)-5,5-dimethyl-4-oxotetrahydrofuran-2-yl]-3-methylocta-2,6-dien-1-yl group at position 3, chlorine at position 5, and a methyl group at position 6. A meroterpenoid produced by the soil fungus, Acremonium sclerotigenum. It is a promising drug candidate against the tropical disease, African trypanosomiasis. | ascofuranone |
decan-4-olide | A gamma-lactone that is oxolan-2-one substituted by a hexyl group at position 5. | gamma-decalactone |
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 8 (6.30) | 18.7374 |
1990's | 8 (6.30) | 18.2507 |
2000's | 42 (33.07) | 29.6817 |
2010's | 46 (36.22) | 24.3611 |
2020's | 23 (18.11) | 2.80 |
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 14 (10.85%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 115 (89.15%) | 84.16% |