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non-proteinogenic amino acid derivative

Any derivative of a non-proteinogenic amino acid resulting from reaction at an amino group or carboxy group, or from the replacement of any hydrogen by a heteroatom.

ChEBI ID: 83812

Members (5)

MemberDefinitionRole
3-hydroxynorvalineA non-proteinogenic amino-acid derivative that is norvaline (2-aminopentanoic acid) in which a hydrogen at position 3 is replaced by a hydroxy group.3-hydroxynorvaline
ly 404039An organic heterobicyclic compound that is (1S,5R)-2-thiabicyclo[3.1.0]hexane carrying oxo, oxo, amino, carboxy, and carboxy groups at positions 2, 2, 4S, 4S, and 6S, respectively. It is a potent agonist of group II metabotropic glutamate receptors mGluR2 mGluR3 (Ki = 149 nM and 92 nM, respectively) and exhibits antipsychotic and anxiolytic efficacy in animal models.LY404039
n-nitrososarcosineA nitrosamine that is sarcosine in which the hydrogen attached to the nitrogen has been replaced by a nitroso group.N-nitrososarcosine
n'-formylkynurenineN-formyl-L-kynurenine zwitterion; N-formyl-L-kynurenine
ucb 34714A non-proteinogenic amino acid derivative that is butanamide in which the pro-S hydrogen at position 2 is replaced by a (4R)-2-oxo-4-propylpyrrolidin-1-yl. Used for treatment of partial onset seizures related to epilepsy.brivaracetam

Research

Studies (374)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199036 (9.63)18.7374
1990's22 (5.88)18.2507
2000's37 (9.89)29.6817
2010's169 (45.19)24.3611
2020's110 (29.41)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials65 (16.67%)5.53%
Reviews67 (17.18%)6.00%
Case Studies9 (2.31%)4.05%
Observational8 (2.05%)0.25%
Other241 (61.79%)84.16%