Classes > ethyl 2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate
Page last updated: 2024-08-05 13:36:40
ethyl 2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate
An amino acid ester that is the ethyl ester of cyclohex-3-ene-1-carboxylic acid in which the cyclohexane ring is substituted at positions 1 and 2 by phenyl and dimethylamino groups, respectively. It has four possible diastereoisomers; the opioid analgesic drug tilidine is a racemate comprising the two trans diastereoisomers.
ChEBI ID: 77817
Members (1)
| Member | Definition | Role |
|---|
| ent-dextilidine | An ethyl 2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate that has R configuration at the carbon bearing the phenyl group and S configuration at the carbon bearing the dimethylamino group. It is the enantiomer of dextilidine; the opioid analgesic tilidine is the racemate comprising equimolar amounts of dextilidine and ent-dextilidine. | ent-dextilidine |
Research
Studies (143)
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|
| pre-1990 | 74 (51.75) | 18.7374 |
| 1990's | 20 (13.99) | 18.2507 |
| 2000's | 25 (17.48) | 29.6817 |
| 2010's | 19 (13.29) | 24.3611 |
| 2020's | 5 (3.50) | 2.80 |
Study Types
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|
| Trials | 36 (24.32%) | 5.53% |
| Reviews | 4 (2.70%) | 6.00% |
| Case Studies | 15 (10.14%) | 4.05% |
| Observational | 1 (0.68%) | 0.25% |
| Other | 92 (62.16%) | 84.16% |