Page last updated: 2024-08-05 12:25:26

diazepanone

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ChEBI ID: 46948

Members (2)

MemberDefinitionRole
dmp 323A 1,3-diazepanone ring with two 4-(hydroxymethyl)benzyl groups as substituents at positions N-1 and N-4, two benzyl groups at C-4 and C-7, and two hydroxy groups at C-5 and C-6 respectively.(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis[4-(hydroxymethyl)benzyl]-1,3-diazepan-2-one
xv 638A member of the class of diazepanones that is 1,3-diazepane which is substituted by a 3-(1,3-thiazol-2-ylcarbamoyl)benzyl group at positions 1 and 3, oxo group at position 2, hydroxy groups at positions 5S and 6S, and benzyl groups at positions 4R and 7R. It is a potent HIV-1 protease inhibitor.XV638

Research

Studies (40)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-19900 (0.00)18.7374
1990's27 (67.50)18.2507
2000's10 (25.00)29.6817
2010's3 (7.50)24.3611
2020's0 (0.00)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (2.13%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other46 (97.87%)84.16%