Page last updated: 2024-08-05 12:19:55

bromoindole

An organobromine compound that is a compound based on an indole skeleton, containing one or more bromine atoms.

ChEBI ID: 52514

Members (4)

MemberDefinitionRole
5-bromo-4-chloroindoxyl acetateAn acetate ester obtained by formal condensation of the carboxy group of acetic acid with the hydroxy group of 5-bromo-4-chloroindoxyl.5-bromo-4-chloro-3-indolyl acetate
6-bromotryptophanA bromoamino acid that is L-tryptophan in which the hydrogen at position 6 of the indole ring is substituted by bromine.L-6'-bromotryptophan zwitterion; L-6'-bromotryptophan
bnps-skatoleA bromoindole that is 3H-indole in which the hydrogen at position 2 has been replaced by an (o-nitrophenyl)sulfanyl group and in which the hydrogens at position 3 have been replaced by a bromine and a methyl group. It is used particularly for the selective cleavage of tryptophanyl peptide bonds (cleavage occurs at peptide bonds after amino acids with available C(gamma)=C(delta) double bonds such as tryptophan, tyrosine, and histidine).BNPS-skatole
bromodeoxytopsentinAn aromatic ketone that is imidazole which is substituted by a 1H-indole-3-carbonyl group and a 6-bromo-1H-indol-3-yl group at positions 2 and 4, respectively. Isolated from the Mediterranean shallow-water sponge, Topsentia genetrix. It is a potent inhibitor of MRSA pyruvate kinase and exhibits antibacterial properties.bromodeoxytopsentin

Research

Studies (68)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199031 (45.59)18.7374
1990's14 (20.59)18.2507
2000's11 (16.18)29.6817
2010's8 (11.76)24.3611
2020's4 (5.88)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews5 (7.35%)6.00%
Case Studies1 (1.47%)4.05%
Observational0 (0.00%)0.25%
Other62 (91.18%)84.16%