An amino acid with a structure in which a phenyl ring is bonded to the alpha-carbon of glycine.
ChEBI ID: 55484
There are 4 compounds belonging to this class, involving 1 studies.
| Member | Definition | Role |
|---|---|---|
| L-alpha-phenylglycine | The S stereoisomer of alpha-phenylglycine. | ; |
| D-alpha-phenylglycine | The R stereoisomer of alpha-phenylglycine. | ; |
| Pre-1990 | 1990-2000 | 2001-2010 | 2011-2020 | Post-2020 |
|---|---|---|---|---|
| 0 | 0 | 1 | 0 | 0 |
| Article |
|---|
Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.
A series of alpha-amino acids were identified as ligands which compete with gabapentin for binding to the alpha(2)delta subunit of voltage-dependent Ca(2+) channels. Potent analogs were identified. Their activity in an in vivo pain assay is described. |