Hydroxy-octadecadienoic acids, formed in mammalian cells from the corresponding hydroperoxy compounds (HPODEs).
ChEBI ID: 36328
| Member | Definition | Role |
|---|---|---|
| 11-hydroxy-9,12-octadecadienoic acid | A HODE that is linoleic acid carrying a single hydroxy substituent at position 11. | (9Z,12Z)-11-hydroxyoctadecadienoic acid |
| 13(S)-HODE | An HODE (hydroxyoctadecadienoic acid) in which the double bonds are at positions 9 and 11 (E and Z geometry, respectively) and the hydroxy group is at position 13 (with S-configuration). | 13(S)-HODE |
| 9-hydroxy-10,12-octadecadienoic acid | A HODE that consists of (10E,12Z)-octadecadienoic acid with the hydroxy substituent located at position 9. | 9-HODE; alpha-dimorphecolic acid |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 14 (10.22) | 18.7374 |
| 1990's | 56 (40.88) | 18.2507 |
| 2000's | 26 (18.98) | 29.6817 |
| 2010's | 37 (27.01) | 24.3611 |
| 2020's | 4 (2.92) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 2 (1.42%) | 5.53% |
| Reviews | 4 (2.84%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 1 (0.71%) | 0.25% |
| Other | 134 (95.04%) | 84.16% |