Any fatty acid with a hydroxy functional group in the beta- or 3-position. beta-Hydroxy fatty acids accumulate during cardiac hypoxia, and can also be used as chemical markers of bacterial endotoxins.
ChEBI ID: 59845
| Member | Definition | Role |
|---|---|---|
| 3-hydroxydodecanoic acid | A medium-chain fatty acid that is the 3-hydroxylated derivative of lauric acid; associated with fatty acid metabolic disorders. | 3-hydroxylauric acid |
| 3-hydroxyoctanoic acid | An 8-carbon, beta-hydroxy fatty acid which may be a marker for primary defects of beta-hydroxy fatty acid metabolism. Repeating unit of poly(3-hydroxyoctanoic acid), a biopolymer used by numerous bacterial species as carbon and energy reserves. | 3-hydroxyoctanoic acid |
| 3,4-dihydroxybutanoic acid | A omega-hydroxy fatty acid that is butyric acid substituted by hydroxy groups at positions 3 and 4 respectively. | 3,4-dihydroxybutyric acid |
| beta-hydroxymyristic acid | A 3-hydroxy fatty acid that is tetradecanoic (myristic) acid substituted at position 3 by a hydroxy group | 3-hydroxytetradecanoic acid |
| beta-hydroxyvaleric acid | A short-chain fatty acid that is valeric acid in which one of the methylene hydrogens at position 3 has been replaced by a hydroxy group. | 3-hydroxypentanoic acid |
| corynomycolic acid | A thirty-two membered mycolic acid consisting of 3-hydroxystearic acid having a tetradecyl group at the 2-position. | corynomycolic acid |
| myrmicacin | A medium-chain fatty acid that is decanoic acid substituted at position 3 by a hydroxy group. | 3-hydroxydecanoic acid |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 29 (10.74) | 18.7374 |
| 1990's | 31 (11.48) | 18.2507 |
| 2000's | 61 (22.59) | 29.6817 |
| 2010's | 108 (40.00) | 24.3611 |
| 2020's | 41 (15.19) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 6 (2.03%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 2 (0.68%) | 0.25% |
| Other | 287 (97.29%) | 84.16% |